Hemostatic collagen sponge - official* instructions for use. Instructions for use of collagen hemostatic sponge for nosebleeds or dentistry

An effective antihemorrhagic agent necessary to stop bleeding and used as a local antiseptic is a hemostatic sponge. In this generally accessible way, you can not only stop severe bleeding, but also speed up the process of regeneration of damaged tissue. The collagen sponge has a wide spectrum of action and has found its application in several areas of medicine. Before using an antiseptic, it is recommended to consult with your doctor and ensure storage in your home first aid kit.

Hemostatic sponge

The detailed instructions indicate that this pharmaceutical product simultaneously combines the functions of a sorbent and an antiseptic and helps to avoid bacterial infection of open wounds. The composition of this drug is natural, so the only contraindication for use is the body’s hypersensitivity to the active substances. The mechanism of action of a hemostatic sponge is approximately as follows: upon contact with a damaged surface, platelet adhesion and aggregation occurs, as a result of which bleeding stops.

Compound

The collagen hemostatic sponge is made from a special collagen solution extracted from the tendons and skin of cattle. Auxiliary components in the natural composition of this medicinal product for external use are boric acid, nitrofural and furatsilin. This unique composition does not dissolve in organic solvents, is integral in water, but at the same time is productively absorbed into the wound, forming a so-called protective barrier. The hemostatic sponge is resistant to elevated temperatures up to 75 degrees.

pharmachologic effect

In terms of its pharmacological properties, this medical product has no analogues in its natural composition and is sold in every pharmacy. The hemostatic sponge not only prevents bleeding and large-scale blood loss, but also restores the integrity of damaged vessels and accelerates the process of restoration of damaged epidermal tissue. This universal remedy has bactericidal, aseptic, antimicrobial, regenerating, tonic and sorbing properties, and has a targeted effect on the source of pathology.

Release form

Essentially, it is a pressed yellow powder mass that has a mild odor of acetic acid. It dissolves in the body over 4-6 weeks, while the active substances overcome the systemic blood flow and maintain their concentration for several days. The hemostatic sponge productively absorbs biological fluids, slightly increasing in size and swelling. The dimensions of such a plate are 50x50 mm or 90x90 mm, packed in a plastic bag with cardboard packaging on top.

Indications for use

The hemostatic sponge stops heavy bleeding of parenchymal, alveolar and capillary origin. This medicine must be used immediately, without waiting for heavy blood loss. You must act according to the instructions included in the package. The attending physician strongly recommends using such a pharmaceutical product for its intended purpose in the following clinical pictures, without violating the method of use, daily doses, general advice:

mechanical or chemical damage to the integrity of the skin;
defects of parenchymal organs, as an option - liver, gall bladder;
trophic ulcers of different localization;
hemorrhages of the sinuses of the dura mater;
progressive bedsores, open wounds;
nosebleeds of unknown etiology;
acute otitis;
inflammation of internal and external hemorrhoids;
closure of the gallbladder bed after cholecystectomy;
progressive hemostasis of dental practice.

Hemostatic sponge - instructions for use

This medication is intended for external use to pack an open wound. The dry substance-solution is applied over the open wound, then wait a few minutes. During this time, the hemostatic sponge fills with blood and the bleeding stops. Its edges fit tightly to the wound, but for greater reliability it is better to use a second sponge on top of the first. When the hemorrhage has stopped, the treatment agent is fixed with a U-shaped suture and a bandage is applied. To enhance the effect, the sponge must be moistened with thrombin solution.

If you use a hemostatic sponge with Ambien, the rules for use are somewhat different. The contents of the bottle are intended for tamponing the cavity of an open wound, and the product itself must be held with a surgical instrument and a gauze swab for 5 minutes. You can leave a layer of gauze in the wound for a short period of time, but it must be removed the next day. A hemostatic sponge after tooth extraction is used exactly according to this principle. The attending physician will advise you on the correct choice of prescription and intensive therapy regimen.

Side effects

Not all patients are allowed to stop bleeding using a hemostatic sponge, since side effects may occur in the form of allergic, local reactions on the skin. This is itching, burning, redness, increased swelling of the dermis. Therefore, if the body is hypersensitive to the active substances, it is better not to use the drug after surgery and during intensive care. In addition, doctors do not exclude the risk of secondary infection. Detailed instructions for using the hemostatic sponge do not report other side effects.

Contraindications

If the surface of the dermis is damaged, not all patients are allowed to use this inexpensive drug, since there are medical restrictions. For example, in case of arterial bleeding from large vessels after resection, it is better not to use a hemostatic sponge. This drug should be prescribed to a child with caution, but it is strictly prohibited if the body is hypersensitive to the active components. So dissolving the product in the cavity of an open wound does not help all patients, as stated in the detailed instructions.

Storage conditions

The sponge must be stored in a dry place, since with high humidity this medicine will soon become unusable. The instructions say that such a local antiseptic should not fall into the hands of children or be used for other purposes. Self-medication is possible, especially if you immediately need to stop heavy bleeding. There is an expiration date written on the packaging, which is also important not to violate, otherwise you may not get the desired result. The family first aid kit is the best place to store a hemostatic sponge.

Analogs

Some patients believe that a hemostatic sponge is not able to stop bleeding and alleviate the patient’s plight. In reality, the effect of this medication is selective, and it is also important to consider the risk of side effects. In such clinical pictures, the attending physician introduces a replacement and suggests using an analogue of the specified pharmacological group. Here is a replacement worthy of modern pharmacology, which can also be purchased on the open market, but after consulting with your doctor.

The information is posted on the site for informational purposes only.

Consultation with a specialist is required.

If you find an error in the text, an incorrect review or incorrect information in the description, we ask you to report this to the site administrator.

Reviews posted on this site are the personal opinions of the people who wrote them. Don't self-medicate!

Review: Collagen hemostatic sponge Innopharm Laboratory - we only learned about it through the ambulance

Effectively and quickly stops bleeding, does not require removal

At first none of us were afraid. Remembering from school that in such cases you need to take a semi-sitting position and put cold on the bridge of your nose, I sat my mother down and applied a cloth with ice to her nose (fortunately, it was in the refrigerator). However, 10 minutes passed and the bleeding did not stop, it even intensified. Mom was pounding with fear, her blood pressure jumped sharply, which further aggravated the situation, and in a panic I rushed to the bathroom and back, not having time to rinse the rags. Naturally, they called an ambulance, but it arrived only after 40 minutes, because there were no available teams. During this time, my mother lost a lot of blood, the towel was soaked through.

When the doctors finally arrived, I was hardly in better condition than my mother. As first aid was provided, the nurse advised that in the future, in such cases, insert a cotton-gauze swab soaked in hydrogen peroxide into the nostril. And the doctor, having carried out simple manipulations, quickly stopped the bleeding and showed me the hemostatic sponge with which he did this, asking if we had one in the first aid kit. I replied that no, it was the first time in my life that I had seen such a thing, especially since no one had suffered from nosebleeds before. The doctor advised me to buy such a sponge at the pharmacy and, if necessary, stop the bleeding myself by cutting out a piece of the sponge of the required size and tightly packing the nostril with it. Of course, the next day I bought such a sponge at the pharmacy and read the instructions.

As it turns out, the sponge is made of collagen. Collagen is a building material and an active participant in the healing process; it stops bleeding. The sponge also contains aminocaproic acid with antiallergic activity.

Another component, arovit, is a water-polymer solution of silver nanoparticles that has an antimicrobial and disinfectant effect. Well, boric acid, which completes the list, has an antiseptic, astringent and drying effect.

Returning to our story, I want to say that after packing with a sponge, we calmly arrived at the city hospital, within half an hour nothing leaked anywhere, no additional napkin was required. Later, at the clinic, my mother had the vessel cauterized; I hope this nightmare will not happen again.

And having studied the information about emergency care for nosebleeds, I think it would be useful to remind the readers of Otzovik the main actions in this situation if you don’t have such a sponge at hand or if you don’t have the opportunity to make a cotton-gauze swab.

First of all, you need to calm down. Nosebleeds, although scary, are still not fatal, because there are no large blood vessels in the nose, but only a dense capillary network. This applies, of course, only to “anterior” bleeding that arises from the vessels of the nasal septum; they occur most often - in 90-95% of cases and do not pose a threat to life.

Secondly, you need to take a semi-sitting position, but not leaning back, but rather, slightly tilting your head forward so that the blood does not flow into your mouth.

Thirdly, firmly press your nostrils together with your fingers, thereby squeezing the burst vessel and stopping the bleeding. If your hands are tired, an ordinary wooden clothespin will do for this purpose.

Fourth, put ice on the bridge of the nose so that the blood thromboses faster. Do not blow your nose under any circumstances.

If you decide to use a cotton-gauze swab, then take into account its size: it should be 2.5 - 3 cm in length and 1.5 cm in width. Before inserting, it is better to dip the tampon in a solution of hydrogen peroxide. Install very tightly, blocking the blood flow.

If in this case the bleeding does not stop, then call a doctor.

For myself, I decided that a collagen sponge should be in the home medicine cabinet along with iodine and aspirin; it is especially necessary where there are elderly people suffering from hypertension. I hope my review will be useful to someone. Be healthy!

General impression: We only found out about her through the ambulance.

Tampons Hemostatic sponge - review

Stops bleeding quickly. Be sure to buy this for your home medicine cabinet.

How do you stop bleeding from a nose or wound? Cotton wool? With hydrogen peroxide? Does it help? No to me. Of course, I have both at home. But if there is bleeding, then I only use a hemostatic sponge. It has been in my first aid kit constantly for about 10 years now. Cotton wool doesn’t help me at all, besides, it gets stuck in the wound and then it’s difficult to get it out of there. There is a high probability that when you tear it off or even soak it, blood will flow again.

Briefly about what a hemostatic sponge is.

The hemostatic sponge actually resembles a sponge in appearance. Yellow or slightly brown. But the composition of this sponge is unusual. It is made, just don't faint, from the skin and tendons of cattle. But not like sausage or minced meat, of course. And using special medical technology. Collagen is created from primary raw materials, furatsilin and boric acid are added. And all this equipment is capable of stopping the bleeding and disinfecting the wound in a matter of seconds.

Once, while chopping cabbage with a double-bladed knife, I cut my finger very badly with the second blade. She cut deeply, part of the skin came off the finger and hung like a flap.

I only had a towel at hand, I wrapped it around my finger, and it immediately got wet through. That is, you understand how severe the bleeding was. By the time I got to the medicine box, I poured everything around. The sponge stopped the bleeding instantly! There is no need to apply the entire sponge to the wound, a small piece is enough, even if there is blood in a stream. The sponge is able to absorb a huge amount of liquid without increasing in size. You can cut it with scissors, but if you don’t have time or scissors at hand, tear it off with your hands, it tears easily. There is no need to remove the sponge from the wound after the bleeding has stopped. The sponge will stick well and protect the wound if you suddenly touch it. It is also not necessary to tear off the sponge after it seems to you that the wound has begun to heal. It will dissolve on its own (like surgical sutures). But if you don’t want to wait, you can soak it in hydrogen peroxide.

I also stop nosebleeds only with this sponge. I insert a small piece of sponge into the nose and after a couple of minutes you can take it out - that’s it, there won’t be any more bleeding.

A scary story with a happy ending.

My husband and father-in-law were hanging furniture cabinets in the kitchen. We have a lot of stones in our walls and my father-in-law came across one of them when he was drilling a hole. The drill fell off and injured his hand. What did it hurt? It tore open the whole palm. Our father-in-law is a strong-willed man, he refused to go to the ambulance and was planning to go himself to the accident by car. They put a whole sponge in his palm (there was no time to adjust the size of the sponge to the wound) and just like that he went to the hospital on his own. There was not a drop of blood in the car. At the hospital I also waited in line to see the doctor, the wound was stitched up, and now everything is fine.

You can buy a sponge at almost any pharmacy. True, the last time I bought it, the pharmacist looked at me as if she was hearing about it for the first time. The girl turned out to be an intern and an experienced pharmacist quickly told her where and what. This is the first time we have sold a sponge in this design. This is usually a box with blue letters. Here - with brown ones and the main word in the name is not “hemostatic”, but “hemostatic” (I wanted to find old boxes for a photo, but apparently I already threw it away). And instead of a yellow sponge, it is slightly brown. Shelf life - 3 years (blue packaging - 5 years). Apparently, a new manufacturer of these sponges has appeared. By the way, he also introduced silver into the composition. But the essence is the same as before.

The cost of a sponge (depending on size) is from 70 to 160 rubles (in pharmacies in our city).

In general, if you still don’t have this product in your home or car first aid kit. be sure to buy it. It may be better if you don’t need it, but if something happens, it will save you.

A hemostatic sponge should be in every first aid kit!

For the first time, I experienced the effect of a hemostatic sponge on myself after the removal of a wisdom tooth, the bleeding did not stop for a long time; I brought it from work (works in a pharmacy) to stop bleeding, but I myself have a medical education and know very well that collagen sponges...

An irreplaceable thing for bleeding! It must be not only in the first aid kit, but also in your purse.

Good day to all! Unfortunately, nosebleeds are not uncommon in our family, so the otolaryngologist advised us to purchase this sponge. THIS IS A REALLY ESSENTIAL AND VERY EFFECTIVE SPONGE! It stops even severe bleeding within a few minutes. Using the sponge…

Is there a little tomboy living in your house? then this product MUST be in your first aid kit!

When my son broke his nose while playing, I ran to apply ice to the bridge of his nose and make cotton swabs to stop the bleeding. At that time, I did not yet know about such a miraculous remedy. And she did it the old fashioned way. The blood stopped flowing.

Hemostatic sponge

Hemostatic collagen sponge

Consisting of a mass of porous structure, the consistency of which is elastic and soft collagen, the hemostatic sponge has a yellow color and a faint vinegary odor. It is characterized by excellent absorption of liquids, accompanied by slight swelling. Cold water and organic solvents do not dissolve the sponge; it can also maintain itself unchanged at temperatures up to 75 degrees. Higher temperatures and increased humidity cause changes in the sponge and can partially dissolve it.

Hemostatic sponge instructions

The instructions for use of the Hemostatic Sponge provide the patient with recommendations for its correct use.

Form, composition, packaging

The drug is produced in the form of plates, the size of which is 10X10 cm or 5X5 cm. They are prepared from a collagen solution, which is obtained from the tendon or skin of cattle.

The constituent components of the drug are the amounts of boric acid and furatsilin necessary for the composition of the sponge.

The hemostatic sponge preparation is packaged sterilely. They are packed in ten pieces in a thick cardboard box.

Storage period and conditions

The drug can be stored for five years provided it is kept in places protected from light with air temperatures ranging from 10 to 30 degrees.

Pharmacology

From the pharmacological side, the drug has an adsorbent, antiseptic and hemostatic effect. It also has a stimulating effect on the process of tissue regeneration.

Indications for use of hemostatic sponge

for capillary bleeding (from the nose, after dental intervention, from the sinuses of the dura mater of the brain);
in case of skin damage, otitis media or bedsores;
in order to fill a defect in a parenchymal organ, for example, after partial excision of the liver or removal of the gall bladder.

Contraindications

Collagen hemostatic sponge application

The hemostatic sponge is used exclusively locally by applying a tampon from it to the bleeding wound. If it was not possible to stop the bleeding, another layer of material should be applied. When the bleeding has stopped, the sponge should not be removed, but rather it should be secured. Then it will completely dissolve.

Hemostatic sponge for nosebleeds

When bleeding from the nose, the Hemostatic sponge helps stop the bleeding, and also acts as a sorbent and antiseptic, stimulating tissue restoration.

Apply the sponge tightly to the bleeding site and check after a few minutes to see if the blood has passed. If necessary, apply another plate. After the blood has completely stopped, secure the sponge (U-shaped fixation).

Hemostatic sponge after tooth extraction

After tooth extraction, the Hemostatic sponge is capable of helping the patient if he needs to stop bleeding. In addition, the sponge will promote an adsorbent and anti-inflammatory effect. While waiting for a preventive result, you can place a sponge in the hole of a newly extracted tooth.

Side effects

The use of a hemostatic sponge may lead to re-infection or the development of allergies.

Drug interactions

The effect of the drug will be enhanced if thrombin is used to wet it.

Hemostatic sponge with Ambien analogues

Analogues of the drug in the form of a collagen hemostatic sponge are some drugs with similar effects:

Hemostatic sponge price

The cost of the drug varies depending on the size of the plates and units in the package. It ranges from 85 to 740 rubles.

Hemostatic sponge reviews

Reviews about the hemostatic sponge preparation are very few, but each of them characterizes the material exclusively on the positive side. Let's look at a few reviews that we received quite recently.

Victoria: The child came from kindergarten and when talking with him, I heard some nasality in his voice. It turned out that his nose started bleeding during the day and the teacher put a hemostatic sponge in his nose. Indeed, by evening the child was breathing normally and upon examination nothing foreign was found in the nasal cavity. An interesting drug. Although I had no idea about its existence before.

Marina: Not long ago I found myself in a rather ridiculous situation when my elderly mother started bleeding from the nasal cavity, and everything that I knew to help in this situation did not work. I had to resort to calling an ambulance. The brigade arrived only twenty-five minutes later. During this time, the woman lost a lot of blood, and I myself was not in the best condition. The nurse calmly rolled up a small swab and placed it right on mom’s nose. A few minutes later the blood calmed down and they showed me our savior in the form of a collagen sponge and taught me how to use it.

How long after it is possible to remove the hemostatic sponge from the nose?

Do I need to wait for some time, or is it removed immediately after the bleeding stops?

I first heard about the concept of a “hemostatic sponge” in the office of a pediatric ENT doctor, when my son and I turned to a specialist for professional help.

The child often bleeds from the nose and had to consult an ENT specialist to rule out or identify problems that lead to bleeding.

For nosebleeds, the doctor prescribed compresses with tampons made from homemade cotton wool, which must be soaked with olive oil or milk thistle oil for 10 minutes in each nostril for 14 days.

And to this, also purchase a hemostatic hemostatic sponge at the pharmacy, which consists of collagen, a suspension of silver, boric acid and aminocaproic acid.

For nosebleeds, you need to cut a small piece so that it fits into the child's nostril and leave for 2-3 minutes to absorb the blood.

Subsequently, the sponge completely dissolves, but I don’t wait for this moment, since the child pulls it out of the nose.

If one plate is not enough and the sponge is completely saturated with blood, it is replaced with a new one and fixed on the wound.

There is no need to remove a collagen hemostatic sponge, because such a sponge has the property of dissolving on its own, and the bleeding quickly stops; by treating it with furatsilin, it has an antiseptic effect, as well as a healing effect on the wound. Do not use such sponges for arterial bleeding and purulent wounds.

Hemostatic sponge

Instructions for use:

Price in online pharmacies:

A hemostatic sponge is an antihemorrhagic or hemostatic agent. The scope of its application is quite wide, and there are few side effects and contraindications. The drug helps stop bleeding and promotes rapid restoration of damaged tissues, limiting their injury and protecting them from negative external influences.

pharmachologic effect

The hemostatic sponge is both a sorbent and an antiseptic; it helps stop bleeding and protects the wound from the development of bacterial infection. In addition, it promotes the rapid restoration of damaged tissues.

The raw material for making a sponge is a collagen solution, which is obtained from the skin and tendons of cattle. Additionally, boric acid and furatsilin are added to the sponges. Thanks to its unique composition, the hemostatic collagen sponge is perfectly absorbed in the wound cavity, but is completely insoluble in cold water and various organic solvents; in addition, it tolerates temperature increases well, up to 75°C.

Very often you can hear recommendations for the use of a hemostatic sponge with Ambien. Ambien is a substance that prevents the dissolution of blood clots. In addition to Ambien, this sponge contains human blood plasma and calcium chloride.

Composition and release form

Hemostatic collagen sponge is available in the form of dry, porous, soft and elastic plates. The plates are yellow in color and have a faint odor of acetic acid. The sponge plates absorb liquid well and swell slightly. The sponge does not dissolve in cold water and organic solvents, but in hot water contraction occurs, as well as partial dissolution of the sponge.

Standard jaws have dimensions of 50*50 mm or 100*100 mm. A sponge with Ambien is produced in the form of a dry substance, packaged in bottles.

Indications

According to the instructions, the hemostatic sponge can be used for a variety of capillary bleeding, for example, nosebleeds, bleeding after dental procedures and from the sinuses of the dura mater. Also, this sponge is often used for parenchymal bleeding or bleeding from internal organs, as well as for alveolar bleeding.

According to the instructions, the hemostatic sponge can be used for skin injuries, including bedsores, as well as for filling defects in parenchymal organs, for example, its use is justified after hepatic resection. It is also used to close the gallbladder bed after cholecystectomy.

Instructions for use (method and dosage)

The method of using the hemostatic sponge is described in detail in the instructions. It is used only locally for wound packing. In about 3-5 minutes, the sponge is completely saturated with blood and fits tightly to the edges of the wound. If bleeding from the wound has not stopped, you can use another sponge; it is placed on top of the first. After the bleeding has stopped, the sponge is fixed using a U-shaped suture. To enhance the effect of using a sponge, it is often recommended to moisten it with a thrombin solution.

The rules for using sponges with Ambien are slightly different from the standard ones: the contents of the bottle with the sponge are used to tampon the wound surface. In this case, the sponge must be pressed with a gauze swab or surgical instrument for 3-5 minutes. If necessary, after pouring the sponge onto the damaged surface, you can add a gauze swab and even leave it in the wound cavity for no longer than a day.

Side effects

When using a sponge, like any other medicine, allergic reactions may occur. Therefore, if there is known hypersensitivity to furatsilin and other natrofulans, it is better to refrain from using a hemostatic sponge. There is also a possibility of secondary infection of the wound when using a sponge.

Contraindications

The use of this sponge is also contraindicated for bleeding from large vessels.

The description posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and does not constitute a guide for self-medication. Before using the medicine, you must consult a specialist and read the instructions approved by the manufacturer.

Hemostatic collagen sponge 50x50mm No. 1

Hemostatic sponge 5X5cm N1

Hemostatic sponge 9x9cm 1 pc.

Hemostatic sponge 9*9 cm N1

When using materials from the site, the active reference is obligatory.

The information presented on our website should not be used for self-diagnosis and treatment and cannot serve as a substitute for consultation with a doctor. We warn you about the presence of contraindications. Specialist consultation is required.

Instructions for use of collagen hemostatic sponge for nosebleeds or dentistry

Hemostatic sponge

Compound

pharmachologic effect

Release form

Indications for use

mechanical or chemical damage to the integrity of the skin;
defects of parenchymal organs, as an option - liver, gall bladder;
trophic ulcers of different localization;
hemorrhages of the sinuses of the dura mater;
progressive bedsores, open wounds;
nosebleeds of unknown etiology;
acute otitis;
inflammation of internal and external hemorrhoids;
closure of the gallbladder bed after cholecystectomy;
progressive hemostasis of dental practice.

Hemostatic sponge - instructions for use

Side effects

Contraindications

Storage conditions

Analogs

Some patients believe that a hemostatic sponge is not able to stop bleeding and alleviate the patient’s plight. In reality, the effect of this medication is selective, and it is also important to consider the risk of side effects. In such clinical pictures, the attending physician introduces a replacement and suggests using an analogue of the specified pharmacological group. Here is a replacement worthy of modern pharmacology, which can also be purchased over the counter, but after consulting with your doctor first:

Hemostatic sponge price

The specified drug is easy to find on the open market, but it is also easy to order via the Internet on thematic websites from detailed catalogs. In the latter case, it turns out to be somewhat cheaper, and delivery is not delayed. Before making such a relevant purchase for yourself, it is important to find out not how much the hemostatic sponge costs, but whether it is suitable for the patient’s specific clinical picture or not. If there are no medical contraindications for use, you can use reliable information from the table below with metropolitan prices:

Name of pharmacy in Moscow

Cost of the drug 50X50 mm, rubles

Note!

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The hemostatic sponge is an effective antihemorrhagic agent. This hemostatic device is an indispensable assistant to the surgeon performing the operation. You should have a sponge in every home, and especially in your car, first aid kit so that, if necessary, you can quickly stop bleeding. This medical device is a sorbent with antiseptic properties.

The product stops bleeding and activates the restoration of damaged tissue. Another positive thing is that when the sponge is placed into the wound cavity, it completely dissolves without any residue. But it cannot be dissolved in cold liquids (up to 75°C), and it does not lend itself to organic solvents.

The sponge is made from a dense solution of collagen, which is obtained from the processing of tendons, cartilage, skin tissue and some other components of the carcass of large-horned animals. When is a hemostatic collagen sponge used, instructions, application, composition, what are it? To have the most complete understanding of this product, you need to carefully read the instructions.

If this is not possible, please read this description of this tool. It is for informational purposes, compiled on the basis of a factory annotation, but it is not such.

Therefore, if you need to use this product in practice, carefully study the package insert yourself.

Compound

The sponge, as we already know, contains a dense solution of collagen. In addition to it, this product contains a solution of furatsilin, as well as boric acid. It is a dry, very porous mass. The color is yellow and has a slight smell of acetic acid.

Quickly and effectively absorbs liquid substances. At the same time, the sponge swells a little.
Pharmacies offer the product in the form of square plates measuring 100 x 100 mm or 50 x 50 mm. Each package of the drug contains 10 pcs. plates At the same time, for 1 g of collagen sponge there is 0.0125 g of boric acid powder, as well as 0.0075 g of furatsilin.

Indications for use

This medical device is effective in stopping capillary bleeding. Therefore, the sponge is used for nosebleeds. This remedy will help with bleeding resulting from dental procedures. It is also used for parenchymal bleeding of internal organs, as well as for alveolar bleeding from lung tissue.

Recommended for use in the treatment of bedsores and various damage to skin surfaces. Often used after hepatic resection. Used after cholecystectomy, when the gallbladder bed should be closed.

Application. What do the instructions say?

To quickly and effectively stop severe bleeding, cut off the required amount of hemostatic collagen sponge. The required section is applied to the surface of the existing wound. Gradually the bleeding stops (hemostasis effect). After this, there is no need to remove the sponge from the wound, as it will completely dissolve.

If there is a need to enhance the hemostatic effect of this agent, the sponge can be soaked in a thrombin solution before use. If the bleeding is very intense and does not stop, apply a second piece of sponge to the wound. In this case, after the bleeding has stopped, a fixing U-shaped suture is applied.

Very often, the use of a sponge is combined with drugs that prevent blood clots from dissolving, for example, Ambien. This is done as follows: First, treat the surface of the wound with an Ambien solution using tampons. Then lightly press down on the surface of the wound, leaving it there for 5 minutes. Then the wound is sprinkled with a crushed sponge. Or add it inside a gauze swab, which is left in the wound cavity for no more than a day.

The size of the hemostatic sponge plates, as well as their number, is selected depending on the intensity of bleeding, the size of the wound or cavity.

Contraindications

This remedy is not used in case of heavy bleeding due to damage to large blood vessels. The use of the sponge is contraindicated in patients whose bodies are particularly sensitive to furatsilin, as well as other nitrofurans.

Side effects

When using a sponge, allergic reactions are possible.

It is recommended that you obtain medical advice before using this hemostatic agent. Be healthy!

A hemostatic sponge is an effective hemostatic agent that is widely used in various fields of medicine, in particular in dentistry after tooth extraction.

It has sorbent and antiseptic properties, while stopping blood and protecting the wound from pathogenic bacteria entering it. In addition, the product promotes rapid healing of damaged socket tissue.

Varieties

After tooth extraction, the remedy is used not only to stop bleeding, but also to prevent the development of possible inflammatory complications in the case of complex surgical intervention, such as wisdom tooth extraction.

In a routine procedure for removing a unit of dentition, a collagen hemostatic sponge is used to stop bleeding.

After surgery, when an inflammatory process in the socket may develop, doctors recommend the use of a special alveolar compress “Alvostaz”, which also has the form of a sponge. It has hemostatic and antiseptic properties and is used for the prevention and treatment of alveolitis.

Release form

The hemostatic sponge is a pressed dark yellow powder with a faint odor of acetic acid. Sponges are produced in the form of square plates measuring 50x50 mm or 90x90 mm and have a dry porous elastic structure.

At production, they are placed in tightly closed plastic bags, and then packaged individually in cardboard packages.

The sponges absorb liquid well, while swelling slightly. They do not dissolve in cold water and organic substances, but are subject to partial dissolution in water having a temperature above 75 degrees.

Pressed plates are made from a collagen solution obtained from the skin and tendons of cattle. Substances such as nitrofural and boric acid are used as additional components.

One of the most effective is the “Alvostaz” product, which is packaged in plastic jars of 30 hemostatic sponges soaked in a medicinal solution, measuring 1x1 cm. It is produced in 3 versions and contains eugenol, iodoform, thymol, lidocaine, tricalcium phosphate and propolis.

How does it work?

The hemostatic agent is used topically for wound packing and has a wide range of actions, including:

bleeding stop;
protecting the wound from the development of bacterial infection;
relief of foci of inflammation;
relief from painful sensations;
preventing swelling of the gum tissue;
accelerating the healing of the hole.

The effect of the product continues for several hours after tooth extraction. After a certain time, the collagen sponge placed on the wound in the gum is completely absorbed.

The cervix is considered to be the junction of the uterus directly with the vagina; it is its narrowest lower part. Its mucous membrane blocks the entry of microorganisms into the uterus, so it is vulnerable and susceptible to diseases such as erosion, inflammation and tumors, and others.

If cancer is suspected or to confirm cytology results, a biopsy procedure is performed - this is the removal of a small area of tissue for further laboratory analysis.

With the help of a biopsy, it became possible to diagnose oncological diseases in a timely manner and prevent their further development.

Papilomavirus damage to cervical tissue has a characteristic morphological sign - the presence of koilocytes as a result of biopsy analysis. Koilocytes are cells with various nuclear lesions and vacuolar degeneration (intracellular edema).

The presence of koilocytes indicates the active presence of the papilloma virus, whereas normally they are absent. This test result does not indicate a cancerous or precancerous condition, but should serve as a signal to a woman to be more attentive to her health and be observed by a gynecologist.

All these local processes indicate keratinization of squamous stratified epithelium of varying severity. Such pathological conditions are not accompanied by any symptoms, but can have clinically pronounced forms, which are diagnosed during a gynecological examination or colposcopy.

Acanthosis, hyperkeratosis, parakeratosis, and leukoplakia are not cancerous or precancerous lesions but should be considered in conjunction with other biopsy findings.

For example, leukoplakia, together with atypia of cells on the cervix, is classified as precancer and is preferably removed along with part of the cervix. Nevertheless, it is recommended to get rid of such pathological processes even if they are not potentially dangerous.

Cervical dysplasia is usually understood as an atypical change in the epithelial cells of the vaginal part, which is classified as cancerous and precancerous processes.

The first stages of this disease are characterized by reversibility, therefore early detection and removal of altered tissues is of great importance in the prevention of cancer in women.

Dysplasia leads to disturbances in the cellular structures of the affected tissues lining the surface of the cervix. As a rule, the disease is detected in patients aged 25–35 years, and they have no complaints or clear clinical manifestations of the disease, therefore laboratory, clinical, and instrumental methods are important to identify the disease.

Lyophilized hygroscopic porous mass

white with a yellowish or yellow with a brown tint with a slight specific odor;

Varieties

Among the sponges used to treat hemorrhoids, two types can be distinguished.

1. Meturacol.

In addition to collagen, this collagen sponge contains methyluracil, which promotes rapid healing of wound surfaces. It is worth noting that such collagen sponges can be used not only in the local treatment of hemorrhoids, but also in surgical practice for ulcerative necrotic lesions, bedsores and trophic ulcers.

Collagen sponges have also been used in gynecological and dental practice in the treatment of mucous membranes that are ulcerative and necrotic in nature.

2. Thrombocol. It is a collagen sponge, which contains high concentrations of blood clotting factors, as well as the antiseptic Sangviritrin. Due to the large number of platelets, these collagen sponges quickly cope with venous bleeding.

1. Curettage is a classic method. The cervical canal is opened using special instruments and first the cervical canal and then its cavity are scraped out. Scrapings are made with a curette under local anesthesia or general anesthesia.

2. Curettage in the form of line scrapings (trains). To do this, use a small curette. The material is taken from the fundus of the uterus to the cervical canal. The method is not suitable for uterine bleeding.

3.Aspiration biopsy is performed by suctioning sections of the mucous membrane. May cause discomfort. The study is not carried out if uterine cancer is suspected, since it is impossible to determine the exact location of the tumor and the extent of its spread.

4. Pipelle endometrial biopsy is the most modern and safe method.

The tissue is collected using a special soft tube - a pipel; inside it has a piston, like a syringe. The pipel is inserted into the uterine cavity and the piston is pulled out halfway, this creates negative pressure in the cylinder, and endometrial tissue is sucked inside.

The procedure lasts several minutes; there is no need to dilate the cervical canal, since the diameter of the pipe is only 3 mm. The procedure is completely painless, complications or negative consequences after it are excluded.

Cervical biopsy has a very important diagnostic value, because its timely implementation helps to show pathologies such as dysplasia, polyposis or cervical cancer.

The procedure is usually prescribed 5-6 days after menstruation. Such research can be carried out in several ways.

Sighting

This type of biopsy is also called punctal and colposcopic. The procedure is carried out using a colposcope, which is a special forceps, which is used to collect biomaterial from the uterine cervix.

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The damaged surface heals approximately 5-6 days after the procedure. The biopsy is taken from a specific, pre-planned area of the cervical canal. Typically, such a biopsy procedure is performed with a special biopsy needle.

Radio wave

A similar method of biopsy of cervical structures is indicated for women who do not have a history of childbirth. Usually, the Surgitron device is used to perform radio wave cervical biopsy.

This biopsy technique is characterized by the absence of traditional consequences such as bleeding. This test is also called radioknife and excisional cervical biopsy.

Knife

The knife procedure for obtaining a biopsy is not particularly common today, like, for example, a loop or radio wave procedure. This procedure is not suitable for nulliparous women.

When performing a knife biopsy, patients must be given anesthesia, and after the procedure the woman is under medical supervision for some time.

After a knife biopsy, a suture is placed that does not require removal. After the procedure, for several days, as with other procedures, patients feel some pain.

The essence of this procedure is that the woman is given traditional anesthesia, after which a piece of cervical tissue is captured by a special loop through which a current is passed. This technique is also called electrosurgical biopsy or electroexcision.

The biopsy sample is taken with an instrument - a loop that passes a low-power electrical discharge. This loop peels off the desired tissue element for laboratory testing.

Circular

When performing a circular biopsy, a large area of cervical tissue is captured; to carry out this procedure, anesthesia is required, and it is somewhat stronger than with a regular biopsy.

The procedure is more painful, and bleeding after it also lasts a little longer (about a month).

Endocervical curettage

During the procedure, the superficial cervical layer is scraped using a curette. The resulting sample is sent for cytological diagnostics.

Laser

Laser biopsy of the uterine cervix involves taking a biopsy sample using a laser knife.

This procedure is performed in a hospital setting because it requires general anesthesia.

This procedure is considered low-traumatic and uncomplicated.

For some time after the analysis, slight spotting of a red-brown or pink color may occur. In general, the procedure has no complications, is painless and is considered financially affordable.

Conchotomnaya

The method of conchotome analysis of a biopsy sample is similar to the colposcopic technique, the only difference is that when performing the procedure, an instrument is used - a conchotome, which is similar to scissors with sharp edges.

Trephine biopsy

A biopsy examination in a similar way is carried out after a colposcopic examination reveals the presence of a large-scale epithelial lesion. The biopsy sample is taken from several areas.

What tests should be done before a cervical biopsy?

The procedure is invasive and is therefore always accompanied by a risk associated with infection by pathogenic microorganisms. To prevent negative consequences, an examination is prescribed before such manipulations.

Generally accepted gynecological practice involves a comprehensive clinical and laboratory examination, including:

coagulogram;
clinical blood test;
colposcopy;
vaginal smear for microflora;
cytological analysis;
examination for hidden infections;
testing for hepatitis, syphilis and HIV.

If laboratory tests reveal at least one of the listed diseases, the biopsy is postponed until recovery after a course of antibiotics.

The average price of a cervical biopsy in Moscow medical centers is about 2000-12590 rubles.

The final cost depends on the status of the hospital and the method of diagnosis.

Indications for use

The scope of application of a hemostatic agent is very diverse. It is used when the integrity of capillaries is violated. The sponge has become widespread in the dental field. Parenchymal and internal bleeding can also be stopped using a hemostatic sponge.

In addition to stopping bleeding, the drug is perfect for damaged skin, including bedsores. In medicine, the sponge is often used on patients who have undergone hepatic resection and cholecystectomy.

Each package of the product contains detailed instructions for its use, which must be strictly followed to avoid complications. The use of a hemostatic sponge has its own nuances and features.

A doctor should prescribe such drugs, taking into account contraindications and possible side effects.

Side effects

The use of a hemostatic sponge after tooth extraction, like any other medication, may be associated with the development of an allergic reaction.

To avoid this, before prescribing the drug, the doctor asks the patient about any cases of individual intolerance to any medicinal components.

When using a hemostatic sponge, there is also a possibility of re-infection of the wound in the gum.

Available contraindications

The product can cause allergies, so the use of a hemostatic sponge is prohibited in case of individual intolerance to its components. It should also not be used for arterial bleeding from large vessels. With great caution, this drug is prescribed to stop bleeding in children.

Application procedure

After removing the sponge from the bag, it is applied to the socket of the extracted tooth. After 3-5 minutes, the bleeding stops, the sponge is saturated with blood and fits tightly to the edges of the wound.

To enhance the therapeutic effect, wetting the sponge with a thrombin solution is recommended.

The use of Alvostaz alveolar compresses has its own characteristics. Before using them, the wound is cleaned with warm saline, after which the doctor suctions it out with a pipette.

The contents of the bottle with Alvostaz are applied to the wound in the gum, and then pressed down with a piece of sterile gauze for several minutes. If necessary, a gauze swab is left in the hole, but not longer than a day.

Local capillary and parenchymal bleeding, bleeding from bones, muscles and tissues, bleeding localized on the surface of the body or in its cavities.

Nosebleeds, gum bleeding and bleeding in patients with thrombocytopenic purpura, leukemia, hemorrhagic thrombocytopathies, Osler-Rendu syndrome, liver cirrhosis, chronic nephritis.

A hemostatic sponge with Ambien is used topically. Before use, remove the drug from the bottle with a sterile instrument.

A single dose depends on the nature and severity of bleeding: use from 1/4 of a sponge to 3-4 sponges. After drying, the bleeding area is tamponed with pieces of a hemostatic sponge with Ambien, pressing them for 3-5 minutes with a sterile gauze ball.

In case of severe bleeding, the hemostatic sponge with amben is pressed to the bleeding surface with a surgical instrument with a flat polished surface to avoid losing part of the hemostatic sponge with amben, as happens when using a gauze ball.

For a soft, longer-lasting tamponade, a hemostatic sponge with Ambien can be placed in a gauze swab. Tampons are removed after 24 hours.

Apply topically. The drug is also used to increase fiorinolytic activity.

There is a danger that the drug may affect the ability to drive a vehicle or operate potentially dangerous machinery.

The conditions for which this drug is used make it impossible to drive a vehicle or operate potentially dangerous machinery.

Porous collagen sponges contain furatsilin and boric acid. They are used by applying a hemostatic sponge to the affected area for several minutes.

Stopping bleeding is based on the ability of the sponge to become saturated with blood and compress blood vessels. Wound healing and antimicrobial action completes the process.

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If internal hemorrhoids bleed, a sponge is inserted into the anus. There is no need to remove it back, since the hemostatic sponge will dissolve over time.

The sponge is used as a hemostatic agent in cases of parenchymal and capillary bleeding of the bone marrow canal, gall bladder bed, alveolar socket after tooth extraction, dural sinuses and parenchymal organs.

The product is also used to stop nosebleeds, for trophic ulcers, otitis media, bedsores and skin damage.

The product is removed from the packaging immediately before use, and it is important to follow the rules of asepsis. Then the sponge is placed on the bleeding area and pressed against it for one or two minutes, or the bleeding area is tightly tamponed over the product and then bandaged.

After soaking in blood, the hemostatic collagen sponge fits tightly to the bleeding surface.

If the gallbladder bed or areas of parenchymal organs are damaged, a sponge is used to cover the damaged areas. In such cases, the product is placed directly on the damaged area.

If the sponge fails to stop the bleeding, a second layer of the product can be applied. In cases of stopping bleeding, the sponge must be fixed with a U-shaped suture. Next, the operation is carried out according to accepted techniques.

In order to stop bleeding from the vascular suture, it is necessary to cover the bleeding area with a sponge. After the bleeding stops, the agent is not removed, because it subsequently completely resolves.

The required quantity and size of the sponge is determined based on the area of the bleeding surface.

The sponge is an effective tool for stopping bleeding from the nose, from the sinuses of the dura mater, as well as during dental procedures, skin injuries, bedsores, otitis, and eye injuries.

A hemostatic sponge is used to fill various defects of parenchymal organs (after liver resection, for example) and to close the gall bladder bed.

The hemostatic sponge is used locally to pack the wound. Remove the drug immediately before use, observing all the necessary antiseptic rules.

After this, the sponge is applied to the bleeding site, pressing against it for 2 minutes, or the surface of the bleeding is tamponed, followed by bandaging. After the sponge is saturated with blood, it fits tightly to the wound.

To close areas of the liver or gallbladder bed after cholecystectomy, a sponge must be placed in the damaged cavity. If the effect is not achieved, you can apply a second layer of hemostatic sponge. After the bleeding has stopped, the sponge should be secured with a U-shaped suture.

In order to stop bleeding from the vascular suture, the bleeding site can be covered with a sponge. After the bleeding has stopped, there is no need to remove the drug, since the sponge is completely absorbed.

The amount of sponge used and the size are selected in accordance with the volume of the cavity and the parameters of the surface being treated.

A hemostatic sponge is used in the following cases:

Nosebleeds;
Trophic ulcers;
Parenchymal and capillary bleeding;
Otitis;
Bedsores;
Damage to the skin.

The drug is also used for bleeding in patients with liver cirrhosis, thrombocytopenic purpura, leukemia, Osler-Rendu syndrome, hemorrhagic thrombocytopathy and chronic nephritis.

The hemostatic collagen sponge is removed from the packaging immediately before use, observing the basic rules of asepsis. It is then placed and lightly pressed against the bleeding area for several minutes.

It is allowed to apply a bandage over the product. After the sponge is saturated with blood, it will fit tightly to the bleeding surface.

In cases of damage to the gallbladder bed, as well as areas of parenchymal organs, a collagen sponge is placed directly into the damaged area.

If applying the product does not stop the bleeding, apply another layer on top of one layer. When the bleeding is stopped, the sponge is fixed with a U-shaped suture, after which the operation is performed in accordance with accepted techniques.

Due to the fact that the hemostatic collagen sponge, when it gets into the area of damage, completely dissolves over time, in cases of bleeding from the vascular suture, it is used to cover the bleeding area and leave it.

The size and quantity of sponge used is determined based on the area of the bleeding surface.

The hemostatic sponge with Ambien is removed from the bottle with a sterile instrument. Next, after quick drying, using a gauze ball, pieces of the product are pressed onto the bleeding surface for 3-5 minutes.

In cases of heavy bleeding, the drug should be pressed against the bleeding surface with a tool with a flat, polished surface. It is not recommended to use a gauze ball, since its removal will entail the removal of part of the product.

It is allowed to spray the crushed sponge using a sprayer or syringe, as well as use it in combination with a tampon for loose tamponade of the cavity. In such cases, the tampon should be removed after 1 day.

The method of using the hemostatic sponge is described in detail in the instructions. It is used only locally for wound packing.

In about 3-5 minutes, the sponge is completely saturated with blood and fits tightly to the edges of the wound. If bleeding from the wound has not stopped, you can use another sponge; it is placed on top of the first.

After the bleeding has stopped, the sponge is fixed using a U-shaped suture. To enhance the effect of using a sponge, it is often recommended to moisten it with a thrombin solution.

The rules for using sponges with Ambien are slightly different from the standard ones: the contents of the bottle with the sponge are used to tampon the wound surface.

In this case, the sponge must be pressed with a gauze swab or surgical instrument for 3-5 minutes. If necessary, after pouring the sponge onto the damaged surface, you can add a gauze swab and even leave it in the wound cavity for no longer than a day.

Complications of the procedure

To avoid possible complications, you must follow your doctor's instructions, which usually include the following restrictions:

You can’t douche for the next six months;
Refuse sexual activity;
Of the water procedures, only a shower is allowed, a bath is strictly unacceptable;
Objects weighing more than 3 kg should not be lifted;
Tampons - no, pads - yes;
Drugs that affect blood clotting are strictly prohibited;
Sauna or bathhouse is absolutely not allowed.

If after a biopsy the patient experiences a pulling sensation in the lower abdomen, blood clots come out of the vagina, frequent changes of pads are necessary, and the discharge has an unpleasant odor, then you should immediately run to the gynecologist.

If symptoms are accompanied by high temperature, then you need to call an ambulance.

To perform the procedure, the woman is released from work for 1-2 days. The manipulation can be performed both on an outpatient basis under local anesthesia, and in the operating room of the gynecological department, when intravenous, epidural anesthesia or general anesthesia is performed.

The type of anesthesia depends on how the procedure will be performed.

To minimize the risk of complications, follow these rules after you have a cervical biopsy:

exclude sexual relations for 2 weeks;
do not lift weights exceeding 3 kg;
do not douche;
use pads rather than tampons;
do not take a horizontal position in the water - wash in the shower;
do not take medications that affect blood clotting;
do not visit the bathhouse/sauna.

If after the manipulation there is a strong pull in the lower abdomen, you have to change pads frequently, blood clots come out, the temperature has risen or there is an unpleasant smell of discharge - consult a doctor. If this happens at night, call an ambulance.

Biopsy, except for puncture and pipel variants, is not at all a routine manipulation and can be complicated:

damage to the vessel with the development of bleeding of varying severity;
suppuration of a postoperative wound;
with a circular or wedge-shaped biopsy, extensive scars or areas in which abnormal epithelium grows for this localization may develop, which will be considered a precancerous condition.

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Indications

Under no circumstances should the product be used for bleeding from arterial vessels.

The following reasons may be an obstacle to performing a biopsy:

systemic diseases of women;
pathologies of the reproductive system;
inflammatory diseases;
blood coagulation disorders;
pregnancy (relative contraindication).

The cervix is penetrated by many small blood vessels; minor damage to them in this case can cause significant blood loss. Although a biopsy is a minor surgical procedure, this procedure is contraindicated in patients with reduced blood clotting.

Hypersensitivity to one of the components of the drug.

bleeding during menopause

bleeding in premenopause

bleeding or light spotting while taking hormonal medications

menstrual irregularities

suspicion of endometrial pathology (hyperplasia, presence of polyps)

uterine fibroids (to assess the endometrium before deciding on the extent of surgery)

chronic inflammatory process (chronic endometritis)

suspected cancer (endometrial cancer)

infertility (to assess the condition of the endometrium)

to monitor the assessment of the condition of the endometrium after hormonal treatment

pregnancy

inflammatory processes in the vagina and cervix

the presence of foci of inflammation in the pelvis

blood diseases: severe anemia, hemophilia, pathologies of the hemostatic system

sexually transmitted diseases

The use of the hemostatic collagen sponge is contraindicated for pyoderma, purulent wounds and arterial bleeding. The product should not be used if the patient is hypersensitive to nitrofuran drugs, as well as to the components that make up the sponge.

The drug is not prescribed for hypersensitivity to the components included in its composition.

The use of the hemostatic sponge is contraindicated in cases of purulent wounds, arterial bleeding and pyoderma.

According to the instructions, the hemostatic sponge can be used for a variety of capillary bleeding, for example, nosebleeds, bleeding after dental procedures and from the sinuses of the dura mater.

Also, this sponge is often used for parenchymal bleeding or bleeding from internal organs, as well as for alveolar bleeding.

It is also used to close the gallbladder bed after cholecystectomy.

The use of this sponge is also contraindicated for bleeding from large vessels.

Biopsy is not performed:

with hypocoagulation (extension of blood clotting time, decrease in prothrombin index, INR);
if there is an inflammatory process in the vagina, uterus or cervix;
during menstrual bleeding;
during pregnancy.

Complications of the procedure

The main complications of the biopsy procedure are infection and bleeding. These events are rare, but women should be informed about the possible negative consequences of a biopsy.

The following symptoms may indicate deviations in the normal recovery period:

heavy bleeding of bright color or dark with blood clots;
bleeding that lasts longer than a week;
light discharge that lasts longer than 2-3 weeks;
temperature rise to 37.5 °C and above;
vaginal discharge with an unpleasant odor.

The cause of the development of infection may be an incompletely cured disease. In this case, to prevent the situation from worsening, a course of antibiotics is prescribed.

Modern methods of hardware biopsy, thanks to the coagulating effect on damaged tissue, make it possible to avoid bleeding and prevent the formation of scars on the mucosa.

As a rule, such types of biopsy as conchotomic, radio wave, laser do not have serious consequences and are characterized by a short recovery period.

After loop and conical (circular and wedge-shaped) biopsies, scar tissue may form on the tissues of the cervix. In the future, these women may have problems with conception, and then with carrying a pregnancy.

The phenomenon of cervical adhesion is quite rare, but leads to infertility due to the fact that sperm are not able to enter the uterus for further fertilization.

A negative consequence of a biopsy can be premature birth. The cervix itself is a kind of muscle that supports the uterus throughout pregnancy.

The operation may cause the cervix to weaken and begin to open prematurely. To avoid this, doctors place stitches in the cervix of pregnant women with similar problems and then remove them before giving birth.

When choosing a biopsy method, the doctor should rely not only on the expected diagnosis, but also take into account the woman’s age and her plans for future motherhood.

After the biopsy, the patient remains able to work, although she has vaginal discharge, which lasts approximately 3-4 days if the biopsy was taken by radio wave.

If a sample of cervical tissue was taken using the loop method, bleeding may last several days (maximum a week).

Tradename: hemostatic collagen sponge

International Nonproprietary Name (INN):

Dosage form: sponge

Compound: per 1 g of the drug: collagen, substance-solution 2% - 49 g (0.98 g of dry collagen), nitrofural (furatsilin) - 0.0075 g, boric acid - 0.0125 g.

Description: yellow plates with a specific smell of acetic acid, with a relief surface, with a porous structure, thickness from 5 to 9 mm.

Pharmacotherapeutic group: hemostatic agent for local use.
ATX CodeВ02ВС07

Pharmacological properties
The drug has a local hemostatic and antiseptic effect, stimulates tissue regeneration. A sponge left in a wound or cavity is completely absorbed. When a hemostatic collagen sponge comes into contact with a bleeding surface, platelet adhesion and aggregation occurs, which leads to a rapid stop of capillary-parenchymal bleeding. Collagen undergoes biodegradation - gradual resorption in the body over 3-6 weeks, which allows the material to be left at the site of application without subsequent removal. Products of collagen biodegradation (lysis) stimulate wound repair processes, accelerating wound healing. The boric acid and nitrofural contained in the sponge have an antiseptic and antimicrobial effect.

Indications for use
as a hemostatic agent for capillary and parenchymal bleeding from:
sinuses of the dura mater;
bone marrow canal;
alveolar socket after tooth extraction;
parenchymal organs (in particular, after liver resection);
gallbladder bed after cholecystectomy.

Contraindications
increased individual sensitivity to the components of the drug. Intolerance to drugs of the nitrofuran series (nitrofural, furazidin, nitrofurantoin, furazolidone, nifuratel, nifuroxazide). Arterial bleeding. Purulent wounds, pyoderma.

Pregnancy and lactation
There are no contraindications for use during pregnancy and lactation.

Directions for use and doses:
The sponge is removed from the packaging immediately before use, observing the rules of asepsis. Apply to the bleeding area and press against it for 1-2 minutes or tightly pack the bleeding surface, followed by bandaging. After soaking in blood, the sponge fits tightly to the bleeding surface. To close damaged areas of parenchymal organs (liver) or the gall bladder bed after cholecystectomy, a sponge is placed in the damaged cavity. If the bleeding does not stop, you can apply a second layer of sponge. After the bleeding has stopped, the sponge is fixed with a U-shaped suture. Further operation is carried out according to accepted methods. To stop bleeding from the vascular suture, the bleeding area is covered with a sponge. After the bleeding has stopped, the sponge is not removed, as it subsequently completely dissolves. The size and quantity of sponge used is selected according to the size of the bleeding surface or the volume of the cavity.

Side effects
allergic reactions are possible.

Overdose
cases of overdose have not been described.

Interaction with other drugs:
the hemostatic effect of the sponge is enhanced if it is additionally moistened with a thrombin solution.

Release form:

Release form:

sponge dimensions (50±5)x(50±5) mm, 1 pc. and (90±10)x(90±10) mm 1 pc. Packed hermetically in two-layer bags made of polyethylene film, or in containers made of polyvinyl chloride film and aluminum foil with a heat-sealable coating, or from films: polymer, "Poliform", "Plastiplen" and laminated paper, or only from films: polymer, "Poliform" , "Plastiplen".
Sponge with a diameter of (11±1) mm, 10, 20, 30 pcs. Packed in blister packs made of... PVC films and aluminum foil with heat-sealable coating.
Blister packaging or two-layer bag made of; polyethylene film or container along with instructions for use are placed in a cardboard box.
For medical institutions, two-layer bags made of polyethylene film or containers of 10, 20, 30 pcs. together with instructions for use in a quantity equal to the number of primary packages, place a cardboard box in a group package.

Storage conditions:
in a dry place, protected from light, at a temperature of 10 to 30°C.
Keep out of the reach of children.

Best before date:
5 years. Do not use after the expiration date stated on the package.

Conditions for dispensing from pharmacies:
over the counter.

Manufacturer/organization accepting consumer complaints:
OJSC Luga Plant Belkozin,
Russia 188230, Leningrad region, Luga, Leningradskoe highway, 137 km