The concentration of uric acid is increasing. Eating foods rich in purines

Uric acid is the end product of the conversion reactions of purine bases, which form the basis of DNA and RNA nucleotides, synthesized mainly by the liver and excreted by the kidneys. It is a heterocyclic compound of carbon, oxygen, nitrogen and hydrogen.

The level of uric acid, determined by a biochemical blood test, indicates the state of health. Shifts in the content of this metabolic product in the blood, both upward and downward, depend on two processes: the formation of acid in the liver and the time of its excretion by the kidneys, which can change due to various pathologies.

Uric acid level

How is the analysis performed?

This type of analysis is prescribed both to assess the state of health during clinical examination, and in the presence of certain diseases for which the indicated indicator may increase (diabetes mellitus, cardiovascular diseases, gout, etc.).

Preparing for the study consists of abstaining from eating for eight hours, i.e. The patient comes for blood sampling on an empty stomach. It is advisable to get tested before taking any medications (antihypertensives, etc.). 1-2 days before the analysis, it is necessary to completely eliminate alcohol, not indulge in foods rich in proteins and purines, and also avoid physical overload.

Venous blood is taken for the study - the indicator is determined in the blood serum. As a rule, the result will be ready within 1 day.

Causes of high uric acid

Arterial hypertension

Already at stage 2 hypertension, an increase in uric acid is observed. Hyperuricemia leads to kidney damage, contributing to the progression of the underlying disease (see). During antihypertensive therapy, uric acid levels can return to normal without specific therapy. If such dynamics are not observed, it is recommended to follow a special diet (see below) and increase physical activity, with further treatment of hyperuricemia.

Gout

When uric acid is elevated at, the reasons are excessive formation of purine bases. With gout, the kidneys are most affected, with the gradual formation of renal failure, as well as the joints, but the changes in them are not so active. The degree of pathological changes correlates with the level of uric acid - the higher it is, the more significantly the kidneys are affected. In addition, hyperuricemia contributes to the development and progression of atherosclerosis and damage to the arterial wall, as a result of which people with gout are more susceptible to cardiovascular pathologies.

Diseases of the endocrine organs: acromegaly, hypoparathyroidism, diabetes mellitus.

For hypoparathyroidism Another characteristic blood indicator is increased calcium mobilized from the bones.

High blood sugar and hyperinsular hormones in diabetes mellitus leads to pathological changes in many types of metabolism, including the destruction of the nuclear material of cells, leading to a secondary increase in uric acid levels, regardless of kidney function.

Acromegaly is caused by excessive synthesis of growth hormone and is manifested by a disproportionate increase in body parts. The pathology is accompanied by a disturbance in the metabolism of purine nucleotides and, accordingly, hyperuricemia.

Obesity

Increased weight often accompanies gout, diabetes, and hypertension. There is a concept of metabolic syndrome, which has been especially relevant in recent decades: obesity + arterial hypertension + diabetes mellitus. Each of these pathologies contributes to hyperuricemia.

Elevated levels of lipoproteins and cholesterol

A frequent precursor to overt clinical manifestations of gout and GA is an asymptomatic increase in these two components of the lipid profile. Atherosclerotic changes in arteries belonging to various vascular systems. Uric acid accelerates the oxidative reactions of low-density lipoproteins and lipid peroxygenation. The oxidative stress created in this way contributes to the progression. In addition, uric acid is involved in platelet aggregation and adhesion, increasing the risk of coronary thrombosis.

Kidney diseases, urolithiasis

Uric acid is a stone-forming substance and contributes to the formation of kidney stones. Reduced excretion of uric acid by the kidneys in a number of pathologies: polycystic kidney disease, nephropathy due to lead poisoning, acidosis and toxicosis of pregnant women.

Blood diseases

In this case, in addition to the breakdown of blood components, there is also a breakdown of tissue components with an increase in the level of purine bases. Hyperuricemia is characteristic of polycythemia, leukemia, B12-deficiency anemia, congenital and acquired hemolytic anemia.

Asymptomatic elevation of uric acid levels

Every fifth resident of Russia and Belarus has an increased level of this metabolic product in the blood without clinical pathology. Based on a number of epidemiological and prospective studies, this condition is considered an independent, powerful and modifiable risk factor for CV events and subsequent mortality.

Other pathologies

Diseases that occur with massive tissue destruction, for example, burn shock. Against the background of renal failure, the time for excretion of the metabolic product by the kidneys increases.
Lesch-Nyhan syndrome, a genetic disorder that causes purines to accumulate in the body. In addition to hyperuricemia, increased levels of acid are also found in the urine.
against the background of purine metabolism disorders.
Erectile dysfunction. An increase in the level of purine metabolism product in the blood increases the risk of developing erectile dysfunction by 6 times.

Nonspecific factors leading to hyperuricemia

The use of a number of drugs - Furosemide, Aspirin, Phenothiazines, Theophylline, Adrenaline, etc.
A diet rich in purine bases. It is known that the second name for gout is a disease of aristocrats with excess meat, fish, red wine, and offal in the diet, i.e. foods containing large amounts of purines.
Drinking alcohol, especially beer and red wines rich in purines. In addition, alcohol negatively affects kidney and liver function, which also contributes to hyperuricemia.
Long-term diets, as a result of which the excretory function of the kidneys is impaired.
Excessive physical activity leads to hyperuricemia due to increased protein consumption, i.e. its collapse.

Symptoms with an increased level of analysis

When uric acid in the blood increases, the symptoms of this condition are always specific depending on the underlying pathology, however, there are also characteristic manifestations that allow one to suspect hyperuricemia:

In adults:
- Tartars
- Increased fatigue
- Chronic fatigue
- Specific symptoms associated with the underlying pathology
In children: bright red spots.

Positive effects of hyperuricemia

Paradoxically, a high level of purine metabolic product in the blood, according to a number of researchers, has a beneficial effect on the body and allows the correction of some pathological conditions:

Numerous studies from the 60-70s. confirmed a higher level of intelligence and reaction speed in patients with acute hyperuricemia. The chemical structure of the acid is similar to trimethylated xanthine caffeine, and as a result, it is believed to be able to increase performance.
Increased acid levels promote longevity by acting as an antioxidant that blocks peroxynitrite, superoxide, and iron-catalyzed oxidative reactions. Transfusion of uric acid enhances the antioxidant activity of blood serum and improves endothelial function.
Uric acid is a powerful neuroprotector, inhibitor of neuroinflammation and neurodegeneration, reducing the risk of and.

However, such a positive effect is observed with an acute increase in acid in the blood. Chronic hyperuricemia leads to endothelial dysfunction and promotes the development of the oxidative process.

What to do if the analysis result is elevated

Detection of elevated levels of uric acid in the blood is the first step in subsequent diagnostics to determine the root cause of this condition. Fundamental is the treatment of the underlying pathology with parallel treatment of hyperuricemia.

A diet for high uric acid includes a decrease in the proportion of protein products in the diet: meat, canned meat and broths, smoked meats, herring, anchovies, sardines, coffee, chocolate, legumes, mushrooms, bananas, alcohol while simultaneously increasing the proportion of fruits and vegetables, fermented milk products, eggs, cereals, cereals. Bran is also recommended.
Fighting excess weight. Often, when weight is normalized, hyperuricemia goes away without specific treatment.
Increasing the daily drinking regimen to 2-3 liters. You can drink pure water or fruit and vegetable juices and fruit drinks diluted half with water.

Drug therapy

All drugs are used strictly as prescribed by a doctor and under his supervision with regular measurements of acid levels in the blood and urine.

Diuretics

Accelerate the elimination of acid by the body through urine. Since some of them increase the concentration of uric acid in the blood and are also contraindicated in a number of pathologies (gout and others), the prescription of drugs from this group is strictly individual and is carried out in a short course with monitoring of blood and urine parameters.

Allopurinol

Inhibits the synthesis of uric acid in the liver by inhibiting the enzyme xanthine oxidase. The treatment is long-term (2-3 months) and requires strict adherence to the frequency of administration. Analogs - Milurit, Zilorik, Foligan, Allopur, Prinol, Apurin, Atizuril, Goticur, Uridoside, Xanthurat, Uriprim.

Benzobromarone

A drug that affects kidney function. It has a uricosuric effect, inhibiting the absorption of acid in the proximal renal tubules, as well as inhibiting enzymes involved in the synthesis of purines. Analogues - Khipurik, Normurat, Dezurik, Exurat, Azabromaron, Maksurik, Urikozurik, Urinorm.

Sulfinpyrazone

Increases the secretion of acid through the urinary system, especially in the initial stages of gout treatment. Analogues - Anturidin, Pirocard, Enturan, Sulfazon, Sulfison.

Etamide

Inhibits the reabsorption of uric acid in the kidney tubules, thereby reducing its concentration in the blood.

Folk remedies

Decoctions of birch buds, nettles and lingonberry leaves are effective, which should be taken 1 glass twice a day for a month.

Low uric acid – pathological causes

Hereditary deficiency of xanthine oxidase, in which uric acid is not formed and is excreted by the kidneys in the form of an intermediate metabolic product - xanthine. Xanthine is not completely eliminated, being partially deposited in skeletal muscles and kidneys.
Hereditary deficiency of purine nucleoside phosphorylase is a disease in which purine bases are not formed.
Acquired xanthine oxidase deficiency associated with allopurinol use and liver disease.
Renal hypouricemia due to mutation of the URAT1 and GLUT9 genes, which control proteins responsible for the reabsorption of acid in the proximal renal tubules.
An increase in the volume of extracellular fluid with large doses of intravenously infused drugs, as well as against the background of polydipsia - severe thirst.
Cerebral syndrome, in which hyponatremia is observed, leading to hyperuricemia.
Parenteral nutrition - specific nutrition is aimed at maintaining vital functions and, naturally, does not contain purines.
HIV infection, in which uric acid deficiency occurs due to brain damage.
Oncological diseases due to protein and purine base deficiency.
Enterocolitis due to impaired protein absorption by the intestinal epithelium.
During early pregnancy, when the total volume of circulating blood increases, uric acid is diluted by an increased volume of the aqueous part of the blood.

Nonspecific factors leading to hypouricemia

Low-purine diet with limited meat and fish. This situation can occur among low-income people or those who deliberately comply with such restrictions.
Abuse of tea and coffee, which have a diuretic effect and help remove acid from the body.
Taking medications: losartan, salicylates, estrogen hormones, trimethoprim, glucose, etc.

Symptoms of low uric acid levels

Loss of skin sensitivity;
, hearing loss;
Asthenia - mood swings, tearfulness, increased fatigue, uncertainty, memory impairment;
In severe cases - paralysis with possible death due to suffocation, multiple sclerosis with multiple damage to nervous tissue.

How to increase uric acid

After finding out the causes of the condition and excluding serious pathologies, you can increase the blood level by normalizing protein intake. In the daily diet at the rate of 1 g of protein per 1 kg of body weight in women, 1.7-2.5 g of protein per kg of body weight in men and at least 1.5 g of protein per kg of body weight in children.

Uric acid– a metabolite of nitrogen (purine) metabolism, a breakdown product of purines, which is always present in a certain amountin the human body and animals.

Uric acid is produced in the liver, contained in the lymph and blood plasma in the form of sodium salts (urates) and excreted by the kidneys.

The salt concentration approaches a saturated solution, so if the normal concentration is exceeded, the urates easily crystallize. Crystals sodium salts uric acid can fall out in the joint fluid, form hard stones (sand, stones) in the kidneys and bladder.

The state of increased levels of uric acid in the blood (hyperuricemia) initially occurs unnoticed by a person. At this stage, hyperuricemia can be detected by a complete blood test for other diseases.

Uric acid levels vary slightly depending on the gender and age of the person (µmol/l):

children under 14 years old – 120 – 320;
women – 150 – 350;
men – 210 – 420.

After 60–65 years, normal values in men and women become approximately the same: from 210 (F) 250 (M) to 480 (F, M) µmol/l.

Uric acid levels in womenlower than in men, due to the relatively lower content of muscle tissue in the body and the lower need for proteins coming from food. During physical activity, accompanied by the destruction of protein molecules of muscle tissue, women produce correspondingly less uric acid.

If the kidneys cannot cope with the excretion of excess urates, the salts begin to crystallize in the joints, causing gouty arthritis; in the kidneys, causing gouty nephropathy. Urates can also be deposited under the skin, forming nodules (tophi). Most often, nodules are found on the ears, elbows, and feet.

Gout – metabolic disease, which consists of crystallization of salts uric acid in various tissues of the body.

To diagnose gout, a blood test is performed to determine the content of uric acid, as well as an examination under a microscope of the contents of the tophi and synovial fluid from the diseased joint for the presence of a crystalline component.

Possible causes of increased concentrations of uric acid in the blood

Hyperuricemia is distinguished between primary and secondary.

Primary - metabolic disordercaused by overproduction uric acid liver while maintaining normal excretory function of the kidneys. May be caused by:

taking certain medications (furosemide, aspirin, theophylline, adrenaline);
a diet with excessive consumption of purine-rich foods (meat, offal, meat broths, some types of fish, legumes, mushrooms);
frequent consumption of red wine and beer;
long-term protein diets to lose weight;
long fasting due to increased protein breakdown, including with a low-calorie diet for the purpose of losing weight;
excessive physical activity accompanied by the breakdown of muscle tissue proteins;
episodic state of dehydration;
hereditary predisposition, which is clearly visible in a number of cases.

Secondary - hyperuricemia is caused by a disease or pathology:

kidney diseases;
some hematological diseases;
products of protein breakdown of cells after radiation therapy;
malignant neoplasms;
destruction of muscle tissue during fasting;
infectious diseases;
liver diseases;
acidosis (violation of the acid-base balance of the body towards acidification, colloquially “acetone”);
alcohol intoxication;
taking certain medications (anti-tuberculosis drugs, aspirin, cytostatics).

An increase in the concentration of uric acid in the blood is promoted by metabolic syndrome, characterized by high levels of blood sugar, free fatty acids (lipids) and low-density lipoproteins (“bad cholesterol”), which also disrupts the purine balance. People with metabolic syndrome usually have abdominal (belly fat) obesity, hypertension, and atherosclerosis.

The classic, typical image of a gout patient is depicted in paintings and fiction: an elderly man with a big belly and a red face sits over a bottle of wine and a hearty meat lunch, nursing a leg with a swollen metatarsophalangeal joint. This often happens.

Excess uric acidcan be episodic - after eating foods rich in purines, physical activity, as a result of a protein or low-calorie diet, stress. Therefore, if the analysis showed hyperuricemia, it should be repeated after a few days, excluding provoking factors (alcohol, protein-rich foods, physical overload).

You need to take the test on an empty stomach, before taking medications. Take a urine test, it informatively reveals the condition of the kidneys. If you suspect urolithiasis, you need to do an ultrasound of the kidneys and bladder.

Symptoms of increased uric acid levels

Hyperuricemia is initially asymptomatic. Moreover, for many people it does not lead to urate crystallization for many years and remains a risk factor. But if the crystallization process has begun, as deposits of excess salts grow, the following may occur:

pain in the joints, in one or two at the same time (metatarsophalangeal joint, knee, wrist, elbow, shoulder). Inflammation of the joints is usually asymmetrical - unlike, for example, deforming arthrosis, which can give similar symptoms. The joint swells, is hot to the touch, the skin is hyperemic. This classic form of gouty arthritis occurs in men. In different statistical samples, the frequency of gouty joint damage ranges from 5 to 50 per 1000 men and from 1 to 9 per 1000 women;
when urates are deposited in the kidneys, pain occurs in the lower back; when hard stones formed by urates move or the ureter is blocked, acute pain (colic) occurs, and blood appears in the urine;
with the growth of stones - urates in the bladder - urination disorders, cystitis;
in children, skin manifestations are more often observed, which can easily be mistaken for allergic diathesis - multiple itchy pink spots on the cheeks, forehead, chest;
increased formation of tartar;
tendency to arterial hypertension, pressure surges.

It should be noted that the reduceduric acid level in bloodalso abnormal. Uric acid stimulates brain function, activates the action of norepinephrine and adrenaline, and is an antioxidant.

How to get rid of excess uric acid

First of all, you need to adjust your diet, making it the basis:

vegetables (except spinach, sorrel, Brussels sprouts), fruits (except bananas);
fermented milk products (except cheese) - kefir, yogurt, low-fat cottage cheese;
whole grain porridge;
lean boiled meat, boiled fish - no more than 3 times a week.

Cannot be consumedproducts containing many purines:

fatty meat, offal (kidneys, liver, brains, tongue);
sausages, usually containing excess fat, salt, soy;
legumes (beans, peas, lentils, soybeans);
mushrooms;
alcoholic drinks (primarily red wines, cognac and beer, containing uric acid precursors).

Minimize:

cheese, butter;
coffee, black tea;
cocoa, chocolate.

It is important to drink enough liquid, including juices, compotes, rosehip decoction, green tea with lemon, and alkaline mineral water.

After just 2 weeks of such a diet, the level of uric acid in the blood should decrease. If a person has a hereditary tendency to increased production of uric acid, such a diet should be constantly followed. Elevateduric acid metabolismIt also has a positive side - people with high synthesis of it are smart, well-educated, have quick reactions, and Alzheimer's disease almost never occurs in them in old age.

Drug treatment

If in the backgrounddiet uric acidin the blood is still elevated, after additional examinations, drug treatment may be prescribed:

diuretics (not all and not everyone - in some cases diuretics can increase the concentration of uric acid in the blood);
allopurinol - inhibiting the action of the enzyme xanthine oxidase, slows downformation of uric acidin the liver (indications: hyperuricemia not controlled by diet, gout, urolithiasis, secondary hyperuricemia of various etiologies);
benzobromarone - inhibits the reabsorption of uric acid in the kidney tubules, inhibits the action of enzymes involved in the synthesis of purines (indications - hyperuricemia, gout);
etamide - increases the excretion of uric acid by the kidneys, preventing its reabsorption (indications - gout, polyarthritis, urolithiasis).

Not all drugs used are listed here, but only the directions of their effect are indicated. In each specific case, the doctor selects the optimal drug.

It is important to maintain a normal balance of uric acid in the body, which is quite possible with a balanced diet, proper drinking regimen, a reasonable lifestyle and periodic monitoring of its content.

Excess uric acid in the blood means that the kidneys are unable to remove it from the body. This is a dangerous condition for the body. What are its reasons?

Elevated levels of uric acid in the blood are called hyperuremia. To bring it back to normal, you need to eat less foods that contain a lot of purines. Excess of these substances accumulates in the joints, forming crystals (some of the purines are excreted from the body in the urine and pass through the intestines). The normal level of uric acid in the blood is expressed by the following indicators: 2.4 to 6.0 mg/dL in women and 3.4 to 7.0 mg/dL in men.

Elevated levels of uric acid in the blood can increase the risk of developing gout and kidney failure. Therefore, it is important to keep these indicators within the normal range and reduce them if the norm is exceeded.

Causes of elevated uric acid levels

One third of the uric acid found in the human body comes from consuming foods and drinks rich in purines.

The other two-thirds of this acid is produced naturally in the body. What are the reasons for increased levels of uric acid in the blood?

1 Poor nutrition

This is usually not the only reason, but excessive consumption of purine-rich foods How meat, fish, canned food, hamburgers, is an important factor in increasing the level of uric acid in the blood. It is also impossible overuse salt, it slows down the removal of uric acid from the body.

2 Refined sugar

Products that contain a lot of sugar are also dangerous in this regard: candies, chocolate, sweet buns, cakes and pastries, sweet drinks, juices sold in stores.

These foods may increase uric acid levels. It's best to avoid them. You can replace sweets with fruits and freshly squeezed juices.

3 Alcohol consumption

Alcoholic drinks cause metabolic disorders in the liver, which involves uric acid. As a result, it accumulates in the body and its content in the blood increases.

Alcohol also negatively affects the intestinal microflora and suppresses the activity of beneficial bacteria in the intestines.

4 Diuretics

These medications increase urine production. They are taken to reduce high blood pressure. At the same time, the kidneys remove more fluid from the body, but for this reason they cannot cope with the removal of the required amount of uric acid.

5 Overweight and obesity

Excess weight is one of the factors in the development of gout. In this disease, uric acid crystals are deposited in the joints.

Obesity, high blood pressure and diabetes contribute to increased production of uric acid in the body. At the same time, its removal from the body slows down.

How to lower uric acid levels in the blood through diet

If your uric acid level is only slightly elevated, it can easily be brought back to normal. through certain dietary changes. High fiber foods reduce uric acid levels and promote its absorption in the intestines.

Foods that are high in fiber:

Spinach
Broccoli

Foods High in Antioxidants:

blueberries and cranberries,
tomatoes,
grape,
Swiss chard.

Integral cereals. You need to include integral grains in your diet.

As for refined carbohydrates (white bread, buns and cakes, sweets), it is better to avoid them. They have virtually no beneficial nutrients.

Try not to include in your diet:

Trans fats
Sugar
Alcoholic drinks
Fats increase the level of triglycerides in the blood, which are deposited on the walls of the arteries. This can lead to a heart attack.
Confectionery and baked goods are also not recommended. They are high in saturated fat and sugar.
Alcohol slows down the removal of uric acid from the body.
And you need to limit your consumption of meat, chicken, and fish. Animal proteins cause high levels of uric acid in the blood

Avoid dehydration of the body: you need to drink more fluids, especially water. This helps eliminate uric acid in the urine. It is recommended to drink two to three liters of water per day.

To prevent fluid retention, you need to limit your salt intake.
Fruits and vegetables should occupy a significant place in the diet.
Limit consumption of red meat and sausages.
Avoid drinking alcoholic beverages.
Exercise regularly. This benefits the joints and the entire body.
Try not to gain excess weight.
Make sure that the body receives a sufficient amount of vitamin C (about 500 mg). It helps reduce uric acid levels.
Drink an infusion of tea and plants such as horsetail and nettle. They help reduce high uric acid levels and are good for the kidneys.
It is important to eat a balanced diet and exercise regularly. This helps maintain health and prevent many diseases. published .

The materials are for informational purposes only. Remember, self-medication is life-threatening; consult a doctor for advice on the use of any medications and treatment methods.

P.S. And remember, just by changing your consumption, we are changing the world together! © econet

Uric acid is a metabolite that is involved in nitrogen metabolism. This product is obtained from the breakdown of purines. Acid production occurs in the liver. Its content is observed in fluids such as blood and lymph. If uric acid in the blood is elevated, then the causes, symptoms and treatment must be fully correlated.

The urinary system is a special mechanism, with its help the body is cleansed of the remnants of the metabolic process. With the coordinated work of organs and systems in the human body, the possibility of related diseases occurring is eliminated.

Uric acid appears in the body in excess quantities when the urinary system is disrupted. The substance enters the blood and spreads throughout the body. A large number of patients wonder what this means. Uric acid can crystallize in internal organs, which leads to the development of various diseases.

Where does uric acid come from?

Uric acid is produced by the liver. When the urinary system malfunctions, acid salts appear in the blood. After this, crystal formation is observed. If increased synthesis is observed in the liver area, uric acid may be formed. The presence of various pathological processes in the body leads to the appearance of salt. If a person eats food that consists of a large amount of purine compounds, then this becomes the cause of pathology.

Normal blood content

After formation, MK dissolves in plasma, which allows it to exit through the kidneys. Uric acid levels directly depend on a person’s age and gender. Uric acid in representatives of the stronger sex should be up to 7 mg/dl. In the female body it should contain up to 5.7 mg/dl. In a child under 14 years of age, the amount of uric acid should be 120-320 µmol/l.

Why does the amount of uric acid in the blood increase?

If uric acid is elevated, this may indicate the influence of various provoking factors. The pathological process is most often observed with frequent consumption of alcoholic beverages, especially wine and beer. If a person uses protein diets for a long period in the fight against excess weight, this becomes the cause of the development of pathology. It may appear during treatment with certain medications:

Furosemide;
Adrenaline;
Theophylline;

Why the rate increases directly depends on a person’s lifestyle. If he fasts for a long time, this leads to increased protein breakdown. Improper nutrition can cause pathology. It is most often diagnosed if a person eats foods that contain purines. In most cases, this is observed when consuming offal, mushrooms, meat and broths made from it, some fish, and legumes.

The pathology is diagnosed with excessive physical exertion, which leads to the breakdown of muscle proteins. An episodic state of dehydration can cause a pathological condition. An increase in the amount of acid is observed with a hereditary predisposition. If a person’s close relatives had the pathology, then he is at risk.

An increase in the amount of uric acid can be diagnosed due to a person’s unhealthy lifestyle. In this case, you just need to adjust it and the indicators will return to normal.

Symptoms of high uric acid in the blood

An increase in the level of uric acid in the blood in the initial stages is characterized by the absence of corresponding symptoms. A large number of patients are at risk for a long period, since crystallization of urates is not observed in them. This situation is quite dangerous, so the patient must be under the supervision of specialists.

If the MK indicator increases significantly, then this affects various organs and systems, which leads to the appearance of corresponding symptoms. Symptoms of increased uric acid manifest themselves in the form of joint pain, which is explained by the inflammatory process. Excess uric acid may increase the formation of urinary stones. If urates are deposited in the kidneys, this causes pain in the lumbar region.

Untimely treatment of the pathological condition leads to an increase in stone size. Against this background, the functioning of the urinary system, which is responsible for removing urine from the body, is disrupted. An excess can cause the development of cystitis, which is accompanied by pain in the lower abdomen. If there is a blockage of the ureter, then the patient is diagnosed with additional disorders. In childhood, skin diseases are most often observed. This is why the diagnosis of allergic diathesis is erroneously made.

With hyperuricemia, pronounced symptoms are observed, and if they occur, it is necessary to seek help from specialists.

Causes of high uric acid in the blood

There are many causes of high uric acid in the blood. Acidity can increase not only with an unhealthy lifestyle, but also against the background of various pathologies in the body. Oversaturation of the body with salts is often diagnosed with prolonged consumption of alcoholic beverages in excess quantities.

Children and adults suffer from a variety of kidney diseases. With metabolic syndrome, an age-related increase in indicators is observed. Pathology can be diagnosed during the period of taking certain medications - aspirin, anti-tuberculosis medications, cytostatics.

Diseases that lead to hyperuricemia

Uric acid can increase in various diseases. If some hematological diseases occur in the body. If fasting is accompanied by the destruction of muscle tissue, then this causes an increase in performance. Pathology is also observed against the background of malignant neoplasms. Liver diseases often lead to increased levels.

If, after radiation therapy, protein breakdown products remain in the body, this leads to the development of a pathological process. Hyperirucemia is diagnosed against the background of infectious diseases. The increase in sUA is explained by acidosis. This is a disturbance in the acid-base balance of the body.

The cause of the development of pathology can be various diseases, including obesity. It should be noted that people with abdominal obesity, in which there is an accumulation of fat in the abdominal area, are at risk. Pathology can also be diagnosed against the background of another disease, for example, atherosclerosis. The development of pathology, especially in women, can be observed with hypertension.

There are a huge number of diseases for which hyperuricemia is diagnosed. That is why it is necessary to treat them in a timely manner, which will avoid the development of a pathological process.

How to treat high urea in the blood?

If uric acid increases in the body, it is necessary to prescribe adequate treatment, which should be comprehensive.

Procedures for high levels of uric acid in the blood

If it rises acid in the blood, then patients are most often recommended to undergo physiotherapeutic procedures:

Stonetherapy. This technique involves warming the body, which leads to the dissolution of uric acid salts.
Herbal medicine. During the treatment period, it is recommended to use herbal medicines. With their help, sodium salts are removed from the body. Also in this case, it is recommended to take medications whose action is aimed at eliminating salt deposits.
Manual therapy. Its action is aimed at restoring blood circulation in the kidneys.
Acupuncture. The technique involves the impact of needles on certain biological buds. Against this background, the pain that accompanies the pathological process decreases.

Only a doctor knows what to do if the amount of uric acid increases. The specialist can determine the most effective therapeutic method according to the individual characteristics of the patient.

Treatment with medications

If uric acid increases, patients are advised to take appropriate medications. In some cases, patients are prescribed medications that have a diuretic effect. Their use is strictly prohibited when large stones are detected, as this can lead to aggravation of the situation.

Allopurinol is a fairly effective medicine in the treatment of the pathological process. The action of the drug is aimed at inhibiting the enzyme xanthine oxidase. When taking the medication regularly, the formation of uric acid in the liver is stopped. Taking the medicine is recommended for gout and urolithiasis. If hyperuricemia cannot be controlled through diet, then patients are also prescribed this medication.

Some patients are prescribed benzbromarone, which inhibits the reabsorption of uric acid in the renal tubules. The drug also inhibits enzymes that are involved in the synthesis of purines. Treatment of the pathological condition is often carried out with Etamide, which enhances the secretion of uric acid by the kidneys. This eliminates the possibility of its reabsorption.

If there is inflammation in the urinary tract, it is recommended to take non-steroidal anti-inflammatory drugs. These medications have anti-inflammatory and analgesic effects, which significantly reduces the severity of the symptoms of the disease. Taking medications should be done with the utmost caution, as they have a negative effect on the digestive tract.

Patients are often prescribed Diacarb, which helps reduce the formation of kidney stones. It also helps dissolve existing stones. Quite often, doctors prescribe anti-gout medications to patients. In most cases, it is recommended to take Sulfinpyrazone or Probenecid. If changes are observed in the urinary tract, then the use of these medications should be carried out with the utmost caution and after prior consultation with a doctor.

Drug therapy is highly effective in the treatment of hyperuricemia. In order for the patient’s treatment to be successful, it is necessary that the drug be selected by a doctor after appropriate diagnosis.

Proper nutrition when sick

When uric acid in the blood increases, patients are required to be prescribed a diet. Quite often, a proper diet can reduce indicators and also alleviate the patient’s condition. In most cases, with a pathological condition, patients are prescribed dietary table No. 5. If a patient is diagnosed with obesity and also has manifestations of gout, then he is recommended to adhere to table No. 8. Patients with hyperuricemia are strictly prohibited from fasting. This is explained by the fact that at the initial stage of fasting there will be a rapid increase in the amount of uric acid, which will lead to an exacerbation of the process.

During the period of exacerbation, it is strictly forbidden to consume foods in the form of fish and meat. Consumption of food is recommended only in liquid form. It is recommended not only to eat the foods the body needs, but also to adhere to the drinking regime. In this case, a person should drink at least two liters of water per day every day.

The patient is advised to stock up on foods that are acceptable for consumption. Patients are advised to eat all fermented milk products. The portion should consist of oranges, nuts, plums. Patients with pathology are recommended to eat pears, apricots, and plums. Main courses can be prepared from a variety of cereals. It is recommended to eat caviar and bread for hyperuricemia. Among vegetables, you should give preference to salad, cucumbers, carrots, and potatoes.

There is a list of prohibited foods that must be excluded from the diet. Beef, pork, and chicken liver is strictly prohibited. The patient should refuse to drink cocoa and coffee. During the course of the disease, consumption of mushrooms is not recommended, especially in dried form. Fresh beans, peas, and lentils must be discarded. The diet should not consist of sorrel, Brussels sprouts, spinach. Cooking is not carried out using strong rich fish and meat broths.

Consumption of fatty meat is strictly prohibited during the course of the disease. If you have hyperuricemia, you should not eat smoked meats, regardless of their type. A person must give up his tongue and kidneys.

Dietary nutrition with an increase in uric acid in the blood should be developed only by a specialist who takes into account individual characteristics and the presence of concomitant diseases. When compiling a menu, the specialist uses a list of prohibited and permitted products.

Traditional recipes for hyperuricemia

If the acid in the blood is increased, then you can use traditional medicine to stabilize the condition, which are characterized by a high level of effectiveness. Today, a variety of folk recipes have been developed, which allows you to choose the most suitable option for a person.

During the course of the pathology, the patient needs to consume artichoke, which is characterized by the presence of a diuretic effect. It must be boiled and eaten. Patients are recommended to prepare first courses using artichoke broth.

In case of exacerbation of gout, apple juices are useful, with the help of which uric acid is removed from the body. When preparing juice, it is recommended to give preference to sweet varieties of apples.

To stabilize the amount of uric acid in the body, it is recommended to take an infusion of chestnut extract. You can buy it at the pharmacy or prepare it yourself. To do this, it is necessary to use several components of the plant: bark, flowers and fruits. All components are crushed and mixed in equal proportions. A tablespoon of the resulting raw material is poured with 250 milliliters of boiling water. The drug is boiled in a water bath for 15 minutes. The medication should be taken 2 times a day. A single dose of the medicine is 20 drops.

If gout causes pain, it is recommended to use nettle to treat it. Fresh leaves of this plant are scalded with boiling water and applied to the sore spot. To reduce pain, it is also recommended to eat fresh strawberry fruits. To remove sodium salts from the body, it is recommended to use potato juice. Also, with the help of this remedy, pain in the joints is combated. If there is pain in the arms and legs, the patient is advised to take baths to which sage tincture is added. To prepare it, you need to take a spoonful of herbs and pour a glass of boiling water. After cooling, the infusion is filtered and used for a bath.

To reduce uric acid levels, it is recommended to prepare a birch decoction. In this case, the foliage of the plant is used, which is pre-crushed and dried. A few tablespoons of raw materials should be poured with 0.5 liters of dill. Boil the medicine over low heat for 15 minutes. After this, it must be left for 30 minutes. After filtering, the medicine must be taken orally with meals. A single dose of the medication is 50 milliliters.

Conclusion

Uric acid is a fairly important indicator of human health. Its increase can lead to the development of quite serious consequences. That is why, when the first symptoms of a pathological process appear, the patient needs to consult a doctor. After examining the patient, the specialist will prescribe adequate treatment using diet, pharmaceuticals, traditional medicines, and physiotherapeutic procedures.

Gout is one of the most painful forms of arthritis. It occurs when too much uric acid accumulates in the body. This disease is more common among men than women. Gout usually results from unhealthy eating habits, so changing your diet is considered one of the best treatments. Medications and other lifestyle changes can really help. See Step 1 to learn more about ways to lower uric acid levels and how to manage or get rid of gout.

Steps

Part 1

Managing your diet

Determine how gout affects the body. A gout attack occurs when the level of uric acid in the blood becomes too high. This leads to the formation of uric acid crystals in joints and other areas. Elevated levels of uric acid can lead to a range of pain symptoms throughout the body.

Because these crystals are heavier than the blood they are contained in, they begin to form deposits throughout the body. However, due to natural gravity, they tend to settle in the lower parts of the body, including between the joints of the big toes.
Kidney stones form when uric acid crystals settle in the kidneys.
Crystalline formations called stones can also form under the skin.

Completely eliminate certain animal products that are high in purine. Certain types of meat, fish and other animal products contain large amounts of purines, which are converted into uric acid. When too much uric acid accumulates in the joints, it results in gout. Completely eliminating the following purine-containing foods from your diet will help mitigate the effects of gout:

Limit your consumption of meat and fish. All types of meat, fish and poultry contain some amount of uric acid. Although you don't have to become a strict vegetarian, reducing your consumption of meat and fish can be an important step in managing the disease. Limit your daily intake to 120-160 g (1 serving) of the following foods:
- Poultry meat
- Red meat (pork, beef and lamb)
- Tuna
- Shrimps
Avoid vegetables, fruits and legumes with high levels of uric acid. Some non-meat foods are also naturally high in purines. These foods tend to promote the formation of uric acid in the blood. The following fruits and vegetables have these properties:
- Mushrooms
- Beans
- Peas
- Lentils
- Bananas
- Avocado
- Pineapples
Limit your fat intake. Excess saturated fat inhibits the body's ability to process uric acid. Avoid eating fried foods and foods high in fat, such as full-fat dairy products. Low-fat foods such as fruits and vegetables, legumes and whole grains will help you manage gout.

Eliminate high fructose corn syrup from your diet. Fructose increases uric acid levels, so avoid sweetened drinks that contain high fructose corn syrup or desserts and other foods that contain it. This is why it is so important to read the labels on packages carefully. This corn syrup is found in many different foods, even those that don't necessarily taste sweet, such as bread or snack foods.
Assess the amount of vitamins and medications you take. People who take a lot of vitamins that contain niacin, as well as certain medications, are at increased risk of developing gout. If you tend to take a lot of vitamins and medications, consult with your doctor to discuss how they may affect your gout. The following supplements and medications may put you at risk for seizures:
- Niacin
- Aspirin
- Diuretics
- Cyclosporine
- Levodopa