Instructions for use of ampoule and capsule forms of vitamin E. Vitamin E in capsules: instructions for use and what it is needed for, price, reviews, analogues

Instructions for use

Attention! The information is provided for informational purposes only. This instruction should not be used as a guide to self-medication. The need for prescription, methods and doses of the drug are determined exclusively by the attending physician.

General characteristics

Composition of the drug:

active ingredient: tocopherol;

1 capsule contains Vitamin (Vitamins- organic substances formed in the body with the help of intestinal microflora or supplied with food, usually plant matter. Necessary for normal metabolism and vital functions) E 0.1 g or 0.2 g;

excipients: sunflower oil; composition of the gelatin capsule shell: gelatin, glycerin, methyl parahydroxybenzoate (E 218), propyl parahydroxybenzoate (E 216), carmoisin dye (E 122).

Dosage form. Soft capsules.

For a dose of 0.1 g: soft gelatin capsules of spherical or spherical shape with a seam, from light red to dark red, filled with an oily liquid from light yellow to dark yellow.

For a dose of 0.2 g: soft gelatin capsules of cylindrical shape with hemispherical ends, with a seam, from light red to dark red, filled with an oily liquid from light yellow to dark yellow.

Pharmacotherapeutic group

Simple vitamin preparations. Tocopherol (Vitamin E). ATS code A11N A03.

Pharmacological properties

Vitamin E is a fat-soluble vitamin that exhibits high antioxidant and radioprotective effects, takes part in the biosynthesis of heme and proteins (Squirrels- natural high-molecular organic compounds. Proteins play an extremely important role: they are the basis of the life process, participate in the construction of cells and tissues, are biocatalysts (enzymes), hormones, respiratory pigments (hemoglobins), protective substances (immunoglobulins), etc.), proliferation (Proliferation(from lat. proles - offspring, offspring and fero - carry) - proliferation of body tissue through new formation (reproduction) of cells. Can be physiological (e.g. normal regeneration, proliferation of mammary gland cells during pregnancy and lactation) and pathological (e.g. tumors)) cells and other important processes of cellular metabolism.

Vitamin E improves oxygen consumption by tissues. It has an angioprotective effect, affecting the tone and permeability of blood vessels, stimulating the formation of new capillaries.

The immunomodulatory effect of Vitamin E is manifested in the stimulation of T-cell and humoral immunity.

Tocopherol is indispensable for normal reproductive processes: fertilization, fetal development, formation and functioning of the reproductive system.

Vitamin E deficiency results in hypotension and dystrophy (Dystrophy- pathological changes in cells of a regressive nature with disruption or loss of their functions) skeletal muscles, myocardium (Myocardium- muscle tissue of the heart, making up the bulk of its mass. Rhythmic coordinated contractions of the myocardium of the ventricles and atria are carried out by the conduction system of the heart), permeability and fragility increases capillaries (Capillaries- the smallest vessels that penetrate organs and tissues. They connect arterioles with venules (the smallest veins) and close the blood circulation), degeneration (Degeneration- rebirth. Pathological changes in cells of a regressive nature with disruption or loss of their functions) photoreceptors, causing visual impairment. Decreased sexual function develops – in men, and menstrual cycle (Menstrual cycle– regularly recurring uterine bleeding, during which a woman loses an average of 50–100 ml of blood. The coagulability of menstrual blood is reduced, so bleeding continues for 3–5 days. The duration of the menstrual cycle is 28 days, it can be less (up to 21 days) or more (up to 30–35 days)), tendency to miscarriage - in women.

Vitamin E deficiency can cause the development of hemolytic jaundice (Jaundice- a painful condition characterized by the accumulation of bilirubin in the blood and its deposition in tissues with a yellow coloration of the skin, mucous membranes, and sclera of the eyes. Observed with increased breakdown of red blood cells (eg, jaundice of newborns, jaundice with hemolytic anemia), viral hepatitis and other liver diseases, obstruction of bile outflow) in newborns, as well as syndrome malabsorption (Malabsorption– malabsorption syndrome. With low absorption (impaired absorption of all food ingredients), a metabolic disorder inevitably occurs - protein, fat, carbohydrate, mineral, water-salt, vitamin metabolism), steatorrhea.

After absorption in the intestine, most of the tocopherol enters the lymph (Lymph- a colorless liquid formed from blood plasma by filtering it into the interstitial spaces and from there into the lymphatic system. Provides metabolism between blood and body tissues) and blood, is quickly distributed in the tissues of the body with predominant accumulation in the liver, muscles, and adipose tissue. The highest concentration is determined in the adrenal glands, pituitary gland (Pituitary- endocrine gland. The pituitary gland is located at the base of the brain and consists of an anterior (adenohypophysis) and posterior (neurohypophysis) lobe. The pituitary gland has a predominant influence on growth, development, metabolic processes, regulates the activity of other endocrine glands), sexual glands (Glands- organs that produce and secrete specific substances that participate in various physiological functions and biochemical processes of the body. The endocrine glands secrete their waste products - hormones - directly into the blood or lymph. Exocrine glands - on the surface of the body, mucous membranes or in the external environment (sweat, salivary, mammary glands)), myocardium. Most of the drug is excreted from the body with urine, partly with bile.

Indications for use

Hypovitaminosis (Hypovitaminosis– a pathological condition caused by a deficiency of a vitamin in the body or a disruption in the functioning of a vitamin in the body) and vitamin E deficiency. In the antioxidant complex therapy (Therapy- 1. The field of medicine that studies internal diseases is one of the oldest and main medical specialties. 2. Part of a word or phrase used to indicate the type of treatment (oxygen therapy\; hemotherapy - treatment with blood products)), the state of convalescence after injuries, severe somatic diseases, with increased physical activity, with an unbalanced diet.

As part of complex therapy:

prevention of pathologies of embryonic development, congenital anomalies (malformations) of the fetus;
threats of abortion;
menstrual irregularities, vulvar kraurosis, menopausal disorders;
perceptual hearing disorders;
atrophic processes in the mucous membrane of the respiratory tract;
degenerative and proliferative changes in joints (Joints- movable joints of bones that allow them to move relative to each other. Auxiliary structures – ligaments, menisci and other structures) And fibrous tissue (Fibrous tissue tissue formed by bundles of collagen fibers with connective tissue cells located among them (fibroblasts, fibrocytes)) spine and large joints; muscle weakness due to discogenic blockades (Blockade- slowing down or interrupting the conduction of electrical impulses in any part of the conduction system of the heart or myocardium) for diseases of the intervertebral disc, scleroderma, lupus erythematosus (Lupus erythematosus– a systemic autoimmune disease in which antibodies produced by the human immune system damage the DNA of healthy cells, mainly connective tissue is damaged), rheumatoid arthritis, other systemic connective tissue diseases;
neurasthenia (Neurasthenia– a psychogenic disease from the group of neuroses, manifested by irritability, increased exhaustion and delayed recovery of mental processes) with exhaustion, predominantly dystrophy and atrophy (Atrophy- reduction in the size of an organ or tissue with disruption (cessation) of their function) muscles, secondary muscle weakness and myopathies (Myopathies– hereditary muscle diseases caused by impaired contractility of muscle fibers. Manifested by muscle weakness, decreased range of active movements, decreased tone, atrophy, and sometimes pseudohypertrophy of muscles) at chronic (Chronic- a long, continuous, protracted process, occurring either constantly or with periodic improvements in the condition) arthritis;
autonomic disorders;
some endocrine disorders;
some cardiovascular diseases;
atrophic processes in the mucous membrane of the digestive system, nutritional disorders, malabsorption syndrome, nutritional anemia, chronic hepatitis;
some periodontopathies;
eye diseases;
skin diseases: dermatitis (Dermatitis– an inflammatory reaction that occurs as a result of direct exposure to external factors on the skin), trophic ulcers, psoriasis (Psoriasis- a chronic hereditary skin disease with diverse clinical manifestations. The most common is ordinary psoriasis - profusely scaly papules and plaques on the scalp, elbows, forearms, hands, legs, feet, lower back, and buttocks. Complaints of itching. In this disease, keratinocytes are formed 28 times more than normal), eczema;
plastic induration of the penis, balanitis, disorders libido (Libido- sexual desire), dysfunction of the gonads in men, disorders spermatogenesis (Spermatogenesis- formation and development of sperm) and potency in men, infertility in men (in combination with vitamin A).
Hypervitaminosis A and D.

Contraindications

Increased individual sensitivity to the active substance or to any components of the drug, severe cardiosclerosis, acute myocardial infarction (Myocardial infarction- ischemic necrosis of the myocardium, caused by a sharp decrease in the blood supply to one of its segments. The basis of MI is an acutely developed thrombus, the formation of which is associated with the rupture of an atherosclerotic plaque), thyrotoxicosis (Thyrotoxicosis- a syndrome caused by the effect of excess thyroxine and triiodothyronine on target tissue. There are many causes of thyrotoxicosis\; the most common cause is diffuse toxic goiter (Graves disease). The clinical picture includes the effect of hormones on different organs. Symptoms of activation of the sympathoadrenal system are characteristic: tachycardia, tremor, sweating, anxiety. These symptoms are eliminated by beta blockers), hypervitaminosis E, children under 12 years of age.

Directions for use and doses

Vitamin E is prescribed orally after meals, the dose is selected individually depending on the disease and the patient’s condition. The capsule should be swallowed whole with plenty of water.

Dosage for adults:

in the complex of antioxidant therapy: 0.2-0.4 g 1-2 times a day;
for pathology of embryonic development, congenital anomalies (malformations) of the fetus: 0.1-0.2 g 1 time per day in the first trimester of pregnancy;
if there is a threat of miscarriage: 0.1 g 1-2 times a day for 14 days;
for menstrual irregularities in complex combination with hormone therapy: 0.3-0.4 g every other day starting from the 17th day of the cycle (repeat 5 cycles);
for menstrual irregularities, if the drug is used before starting hormonal therapy: 0.1 g 1-2 times a day for 2-3 months;
for rheumatoid arthritis: 0.1-0.3 g daily for several weeks;
at muscular dystrophies (Muscular dystrophy– the most common of the hereditary diseases of the neuromuscular system. It is characterized by primary muscle damage and a progressive course. There is muscle weakness and muscle atrophy, a decrease and then disappearance of tendon reflexes), diseases of the neuromuscular and tendon-joint apparatus: 0.1 g 1-2 times a day for 30-60 days, repeat course - after 2-3 months;
for neurasthenia with exhaustion, use the drug: 0.1 g 1 time per day for 30-60 days;
for some endocrine disorders: 0.3-0.5 g per day;
for some cardiovascular diseases: 0.1 g daily;
at nutritional (Nutritional- related to nutrition, food) anemia (Anemia- a group of diseases characterized by a decrease in red blood cells or hemoglobin in the blood): 0.3 g per day for 10 days;
at chronic hepatitis (Chronic hepatitis– damage to hepatocytes caused by various reasons, characterized by hepatocellular necrosis and inflammation, lasting more than 6 months): long-term treatment 0.3 g per day;
for some periodontopathies: 0.2-0.3 g per day;
for eye diseases: 0.1-0.2 g 1-2 times a day for 1-3 weeks in combination with vitamin A;
for skin diseases: 0.1-0.2 g 1-2 times a day for 20-40 days;
for plastic induration of the penis: 0.3-0.4 g daily for several weeks, then as prescribed by a doctor;
for disorders of spermatogenesis and potency in men: 0.1-0.3 g per day in combination with hormonal therapy for 30 days.

In other cases, the dose and duration of treatment are determined by the doctor.

For adults, the average single dose is 0.1 g, the highest single dose is 0.4 g; the highest daily average dose is 0.2 g, the highest daily dose is 1 g.

IN pediatrics (Pediatrics- a field of medicine that studies the characteristics of the child’s body, the causes and mechanisms of development of childhood diseases and develops methods for their treatment) Vitamin E in a dose of 0.1 g can be prescribed to children from 12 years of age.

Features of application

Appropriate safety precautions for use.

Prescribe with caution when atherosclerosis (Atherosclerosis- a systemic disease characterized by damage to the arteries with the formation of lipid (mainly cholesterol) deposits in the inner lining of the vessels, which leads to a narrowing of the lumen of the vessel up to complete blockage), increased risk of thromboembolism.

In rare cases, creatinuria develops, increased creatine kinase activity, increased concentration cholesterol (Cholesterol- a substance from the group of sterols. It is found in significant quantities in nervous and adipose tissues, liver, etc. In vertebrates and humans it is a biochemical precursor of sex hormones, corticosteroids, bile acids, and in insects (supplied with food) - the molting hormone. Excess cholesterol in the human body leads to the formation of gallstones, cholesterol deposition in the walls of blood vessels and other metabolic disorders. Recently, it has been considered more correct to use the term “cholesterol”), thrombophlebitis (Thrombophlebitis- a venous disease characterized by inflammation of the venous wall and thrombosis. The occurrence of thrombophlebitis is preceded by inflammation of the vein - phlebitis and periphlebitis), pulmonary embolism and thrombosis in patients who are prone to it. With epidermolysis bullosa in areas affected alopecia (Alopecia– increased hair loss and insufficient new growth), white hair may begin to grow.

When using the drug, you must adhere to the doses and duration of treatment prescribed by your doctor to prevent overdose and the occurrence of hypervitaminosis E.

With prolonged use of high doses of the drug, it is necessary to monitor blood clotting time.

Use during pregnancy or breastfeeding.

Under the supervision of a physician, the drug can be used in recommended doses during pregnancy or breastfeeding.

The drug partially penetrates the placental barrier; vitamin E enters the fetus’s body, where its amount is 20-30% of the concentration of vitamin E in plasma (Plasma- the liquid part of the blood, which contains formed elements (erythrocytes, leukocytes, platelets). Various diseases (rheumatism, diabetes mellitus, etc.) are diagnosed based on changes in the composition of blood plasma. Medicines are prepared from blood plasma) mother's blood.

Vitamin E also passes into breast milk.

Children.

The drug is contraindicated in children under 12 years of age.

The ability to influence the reaction rate when driving a vehicle or working with other mechanisms.

If dizziness or blurred vision occurs, you should refrain from driving vehicles or operating other machinery.

Side effect

Usually the drug is well tolerated, however, with long-term use of high doses (0.4-0.8 g per day), increased hypothrombinemia, visual disturbances, dizziness, nausea, and the development of gastrointestinal bleeding are possible. diarrhea (Diarrhea- frequent discharge of liquid feces, associated with accelerated passage of intestinal contents due to increased peristalsis, impaired absorption of water in the large intestine and the release of a significant amount of inflammatory secretion by the intestinal wall), stomach pain, liver enlargement, creatinuria, disorder digestion (Digestion- the process of mechanical and chemical processing of food, as a result of which nutrients are absorbed and assimilated, and decay products and undigested substances are removed from the body. Chemical processing of food is carried out mainly by enzymes of digestive juices (saliva, gastric, pancreatic, intestinal juice, bile)), severe fatigue, general weakness, headache. Possible allergic reactions, including skin rash, itching (Itching- a modified feeling of pain caused by irritation of the nerve endings of pain receptors), hyperemia (Hyperemia- plethora caused by increased blood flow to any organ or tissue area (arterial, active hyperemia) or obstructed outflow (venous, passive, congestive hyperemia). Accompanies any inflammation. Artificial hyperemia is caused for therapeutic purposes (compresses, heating pads, cups)) skin and fever.

Interaction with other drugs

Vitamin E should not be used in combination with iron, silver, or alkaline products (sodium bicarbonate, trisamine), anticoagulants (Anticoagulants- drugs that reduce blood clotting) indirect action (dicoumarin, neodicoumarin).

Vitamin E enhances the effect of steroidal and non-steroidal anti-inflammatory drugs (sodium diclofenac, ibuprofen, prednisolone); reduces toxic (Toxic- poisonous, harmful to the body) action of the heart glycosides (Glycosides- organic substances whose molecules consist of a carbohydrate and a non-carbohydrate component (aglycone). Widely distributed in plants, where they can be a form of transport and storage of various substances)(digitoxin, digoxin), vitamins A and D. Prescribing vitamin E in high doses can lead to vitamin A deficiency in the body.

Vitamin E and its metabolites have an antagonistic effect relative to vitamin K.

Vitamin E increases the effectiveness of antiepileptic drugs in patients with epilepsy.

Cholestyramine, colestipol, and mineral oils reduce the absorption of vitamin E.

Overdose

When taking recommended doses, no adverse reactions occur. When taking high doses of the drug (0.4–0.8 g per day for a long time), blurred vision, diarrhea, dizziness, headache, nausea or abdominal cramps, severe fatigue or general weakness are possible.

Very high doses of the drug (exceeding 0.8 g per day for a long time) may increase the risk of bleeding in patients with vitamin K deficiency; may violate metabolism (Metabolism- the totality of all types of transformations of substances and energy in the body, ensuring its development, vital activity and self-reproduction, as well as its connection with the environment and adaptation to changes in external conditions) hormones (Hormones- biologically active substances produced in the body by specialized cells or organs (endocrine glands) and having a targeted effect on the activity of other organs and tissues) thyroid gland (Thyroid gland- endocrine gland. Located on the neck, in the area of the laryngeal cartilages. Consists of two lobes and an isthmus. Produces the hormones thyroxine, triiodothyronine, thyrocalcitonin, which regulate the growth and development of the body (tissue differentiation, metabolic rate, etc.). Damage to the thyroid gland leads to the occurrence of certain diseases (with increased function - thyrotoxicosis, with decreased function - myxedema\; in some areas, due to a lack of iodine in water and soil, the so-called endemic goiter is common, i.e. associated with a certain area) ) and increase the risk of thrombophlebitis and thromboembolism in sensitive patients, increased creatine kinase activity, increased concentrations of cholesterol, triglycerides in the blood serum, increased levels estrogen (Estrogen- pituitary hormone responsible for the maturation of eggs) And androgens (Androgens- male sex hormones, produced mainly by the testes, as well as the adrenal cortex and ovaries. Stimulates the development and function of male genital organs, the development of secondary sexual characteristics. By chemical nature they are steroids. The main representative is testosterone) in urine.

Treatment: drug withdrawal, symptomatic therapy.

General Product Information

Best before date. 2 years.

Storage conditions. In original packaging at a temperature not exceeding 25 °C. Keep out of the reach of children.

Package.

For a dose of 0.1 g.

10 capsules in a blister; 1 blister in a pack.

10 capsules in a blister; 5 blisters per pack.

50 capsules in a blister; 1 blister in a pack.

For a dose of 0.2 g.

10 capsules in a blister; 3 blisters per pack.

Manufacturer.Public Joint Stock Company "Kyiv Vitamin Plant".

Location. 04073, Ukraine, Kyiv, st. Kopylovskaya, 38.

Website. www.vitamin.com.ua

This material is presented in free form on the basis of the official instructions for medical use of the drug.

Vitamin E (tocopherol) is a unique natural compound, an antioxidant with pronounced anti-aging properties. It can be easily purchased at any pharmacy in the form of capsules, oily solution and ampoule injections. Not only internal use and intramuscular administration of tocopherol is used to improve health.

Today, vitamin E is actively used for facial skin as part of various anti-aging masks to restore the former beauty of fading and mature skin. The product is truly very effective and efficient.

The magical effect of vitamin

The active use of vitamin E at home as a cosmetic product is justified by the complex effect it has on the skin of the face.

Rejuvenation:

stops the aging process;
promotes cell regeneration;
smoothes wrinkles;
has a lifting effect, i.e. it tightens the skin, eliminates jowls, saggy folds, double chin;
gives the skin firmness, as if in youth, and pleasant elasticity;
improves blood circulation, which affects a healthy, beautiful complexion.

Antidepressant:

invigorates;
blushes the cheeks;
strengthens the walls of cell membranes;
relieves fatigue.

Antioxidant:

protects cells from free radicals;
removes toxins.

Anti-inflammatory effect:

localizes foci of inflammation;
eliminates acne;
opens and removes blackheads;
relieves acne.

Whitening:

Lightens, making freckles and others almost invisible.

Humidification:

actively moisturizes dry skin;
keeps the water balance in cells under control;
regulates the production of sebum by the endocrine glands.

Medicinal drug:

considered an effective preventive measure against skin cancer;
eliminates external symptoms of allergic skin reactions (peeling, rash, itching, redness);
treats anemia, protecting red blood cells from destruction and thereby saving the facial skin from paleness.

Such a complex effect on the skin makes this pharmaceutical drug very popular not only in home care, but also in modern cosmetology. However, given that this is still a drug, it must be handled with extreme caution. First you need to learn how to use vitamin E for the face at home, and then start preparing anti-aging elixirs.

Where to get vitamin E

Before mastering the art of using vitamin E for the face at home, you need to choose one of its pharmaceutical forms, each of which can become the basis for preparing anti-aging masks.

You can buy vitamin E in capsules of a beautiful translucent amber color, inside of which there is an oily liquid. Usually, vitamin E capsules are pierced with a clean needle, the healing oil is squeezed out and used directly in homemade cosmetic masks.
Oily 50% solution, medically called “Alpha-tocopherol acetate”. This dosage form is more convenient to use for home preparation of masks than capsules, because there is no need to pierce or squeeze anything.
Tocopherol in liquid form (in ampoules) is also very convenient as a base for anti-aging cosmetics.

All of these preparations assume that vitamin E will be used for cosmetic purposes in its pure form with the addition of various auxiliary ingredients. However, if there are contraindications for the external use of this drug (serious diseases of the skin or circulatory system), it will be sufficient to use masks from products in which the tocopherol content is very high:

from fresh vegetables: carrots, radishes, cabbage, potatoes, lettuce, spinach, broccoli, onions;
from berries: viburnum, rowan, cherry, sea buckthorn;
from products of animal origin: egg yolk, milk;
from grains: oatmeal;
from unrefined vegetable oils (pumpkin, corn, olive, sunflower);
from seeds, nuts (pistachios, hazelnuts, peanuts, almonds);
from herbs: alfalfa, raspberry leaves, dandelion, nettle, rose hips, flax seeds.

By including these products in cosmetic face masks, you can fully provide your skin with natural, non-pharmacy vitamin E. Although capsules, oil and ampoules allow you to achieve the desired effect much faster. But at the same time, you need to take into account the medicinal specifics of this drug and handle it at home with extreme care.

Instructions for use

If you already have vitamin E in your hands, you can quickly and easily prepare a miraculous mask based on it. By following basic recommendations, you can get excellent results.

Lubricate your wrist with the acquired liquid and observe the skin reaction. The product can be used if there is no itching or redness.
Steam your facial skin over a steam bath with medicinal herbs.
Clean enlarged pores with a scrub
Apply the vitamin mixture onto the skin in a fairly dense layer along massage lines, trying to avoid the area directly around the eyes.
Lie with the mask on your face for 20 minutes.
Wash with warm water, or milk, or a decoction of medicinal herbs.
Apply daily cream.
Frequency: 1 (in some cases, 2) times a week.
After 10 procedures, take a break for 2 months.

Fast, simple, easy, and most importantly - incredibly effective. Wrinkles will begin to smooth out after the first use, and after 5-6 procedures the rejuvenating effect of vitamin E on the skin will be evident. There shouldn’t be any problems with recipes, since there are a lot of them, and you won’t be limited in choice.

Mask recipes

Face mask with vitamin E and glycerin - perfectly moisturizes dry skin

Vitamin E for external use is rarely used in its pure form. Supplement it with various other ingredients to enhance its effectiveness.

With glycerin

A homemade face mask with vitamin E and glycerin has pronounced moisturizing properties; cosmetologists recommend using it for those with dry skin. Squeeze the oil from 10 tocopherol capsules into a bottle of glycerin (25–30 ml), mix thoroughly, use for several procedures, store in a dark place.

With almond oil

In 3 tbsp. l. 1 tsp of almond oil is added. vitamin E in the form of oil, mix.

With herbs

Mix chamomile and nettle in crushed form (2 tablespoons each), pour a glass of boiling water over them, leave for half an hour, strain. Soak the crumb of rye bread (20 g) in the broth and mash it to a paste. Add 1 ampoule of injectable vitamin E.

With dimexide

Mix 2 tablespoons (full) of castor oil and burdock oil, dissolve the tocopherol oil solution in them. Add 1 tsp. solution of dimexide and water (in equal proportions).

With yolk

Beat almond oil (2 tablespoons) with the yolk, add 1 ampoule of injectable vitamin E.

With sea buckthorn oil

Beat 1 tbsp. l. cocoa butter and sea buckthorn oil, add 1 ampoule of tocopherol.

With cottage cheese

Beat 2 tbsp. l. cottage cheese with 2 tsp. unrefined olive oil, add 1 ampoule of tocopherol.

If you want to quickly and effectively get rid of wrinkles and stop the aging process of your skin, be sure to use vitamin E to rejuvenate your face. This is an effective pharmaceutical drug with a minimum of contraindications and a lot of useful properties, which will magically transform your skin in a short time.

Vitamin E is part of the group of fat-soluble substances. The element is insoluble in water, resistant to high temperatures, as well as to the influence of alkalis and acids. By taking vitamin E, the instructions for use claim that you can normalize blood pressure, improve blood circulation, and strengthen blood vessels. The main function of tocopherol is to protect cells from the negative effects of free radicals.

Release form

This element belongs to the “Vitamins” group. Available in the form of tocopherol as:

Capsules No. 20 (Doppergelz vitamin E forte);
Gelatin soft capsules No. 24 and 60, 400 IU each (Vitrum vitamin E);
Capsules No. 60, 100 IU each (Biovital vitamin E);
Capsules No. 30, 100 IU each (tocopherol acetate);
Capsules No. 100, 200 IU each (alpha tocopherol acetate);
Oily 50% solution No. 10 and 25 in capsules of 0.2 g (alpha tocopherol acetate);
Dragee No. 30, 100 mg (Evitol);
Oily solution for intramuscular injection;
Chewable lozenges.

For those who cannot tolerate the oil solution, capsules are prescribed in dry form.

Vitamin E is also included in multivitamin complexes:

Undevit;
Gendevit;
Aekol;
Aerovit;
Levit et al.

Properties of vitamin E

Element E is necessary for keeping nails, hair, and skin in good condition; it slows down the aging process, and also prevents cancer and negative effects on ultraviolet radiation. This vitamin is an effective and powerful antioxidant. It has vasodilating properties and prevents the oxidative process in the body. Tocopherol protects the lungs from atmospheric pollution, promoting tissue renewal and regeneration, and has a diuretic effect, which has a positive effect on lowering blood pressure.

Indications for use

Vitamin E can be used in complex therapy in the treatment of many diseases:

Hypervitaminosis A and D;
Eye diseases;
Eczema;
Dysfunction of the male reproductive system;
Menstrual irregularities;
Lactation period;
Adaptation period;
Great physical activity;
Osteochondrosis;
Osteoarthritis;
Arthrosis;
Arthritis;
Epilepsy;
Scleroderma;
Lupus erythematosus;
Angina pectoris
Jaundice
Cirrhosis
Hemorrhages
Vascular spasms
Vascular diseases
Disturbance of the sweat glands
Climax
Diseases in newborns
Threat of miscarriage
Hypotrophy
Myopathy
Rheumatism
Degenerative changes in muscle tissue
Amyotrophic syndrome
Asthenic syndrome
Hypovitaminosis E

Dosage

The dosage of element E varies depending on the purpose of its use and age. The need for the vitamin increases among people involved in sports, living in an unfavorable environment, and with hormonal imbalances in the body. An increase in the average dosage is also necessary during pregnancy planning, especially for women prone to spontaneous abortion, as well as men with reduced potency.

Daily vitamin requirement depending on age and gender:

Population category	floor	Daily requirement mg
Infants from 0-6 months	m/same	3
Infants from 7-12 months	m/same	4
Children 1-3 years old	m/same	6
Children 4-10 years old	m/same	7
	men	10
Teenagers and adults from 11 years old	women	8
During pregnancy	women	10
While breastfeeding	women	12
Athletes	m/same	14-30
Elderly people, after 50 years	m/same	10/8

For athletes, tocopherol is dosed taking into account the type and period of exercise.

Admission rules

For adults and children over 12 years of age, element E is prescribed in standard doses orally after meals. When planning conception, the drug is indicated for both women and men in the same daily doses of 10-15 IU. Tocopherol is actively involved in the development and formation of the egg, helps maintain pregnancy in the 1st trimester when there is a threat of miscarriage, helping the embryo to gain a foothold in the uterine cavity, and strengthens the placenta.

For dermatological diseases. The vitamin is prescribed 1-2 times a day. at a dose of 100–200 mg. The course of therapy is from 20 to 40 days;
In the complex treatment of cardiovascular and eye diseases. Prescribed 1-2 rubles/day. 100–200 mg together with element A. Course of therapy 1–3 weeks;
If there is a threat of miscarriage and impaired fetal development in the 1st trimester of pregnancy, the drug is indicated 1-2 times a day. 100 mg for 7–14 days;
In case of hormonal imbalances, tocopherol is prescribed in combination with the main treatment in standard doses. The course of therapy is 30 days;
If potency and spermatogenesis are impaired in men, taking the drug per day is indicated in a dose of 100–300 mg;
For muscle dystrophy, diseases associated with the neuromuscular system and tendon-joint apparatus, the vitamin is prescribed in a dose of 100 mg per day 1-2 times. The course of therapy is 30–60 days, after 2-3 months the treatment is repeated as necessary.

Contraindications

Cardiosclerosis, myocardial infarction, hypersensitivity.

Adverse reactions

With intramuscular administration of the drug, manifestations of allergic reactions, infiltrates and local pain are possible.

Overdose

If you take doses higher than prescribed over a long period of time, the following may develop:

Hemorrhagic stroke;
Ascites;
Retinal hemorrhage;
Hyperbilirubinemia;
Kidney failure;
Hepatomegaly;
Necrotizing colitis;
Sepsis;
Thromboembolism;
Thrombophlebitis;
Hormonal disorders;
Violations;
Visual impairment;
Gastralgia;
Weakness;
Nausea;
Dizziness;
Diarrhea.

If manifestations of some of the listed symptoms are noticed, the drug should be discontinued and consult a doctor. He will prescribe symptomatic therapy and glucocorticosteroids. To avoid an overdose, vitamin E should not be consumed without a doctor’s prescription, since a person receives this element daily through food. Spontaneous administration of the drug can only cause harm.

It is also necessary to strictly adhere to the rules and dosage prescribed by a specialist in a given case. However, one should not be indifferent to this vitamin; without its presence in orgasm, women will not be able to have beautiful hair, healthy skin and nails, and athletes will not score the decisive goal against the opponent.

Vitamin E is one of the group of vitamins of primary importance for the body. It is found in many natural products, primarily of plant origin. However, a person does not always receive the daily requirement of vitamin E from the diet. In this case, dietary supplements with high levels of this and other vitamins, as well as trace elements and amino acids, will come to the rescue. Vitamin E is available in the form of a solution for intramuscular injection, capsules, lozenges, and also as a liquid for oral administration.

The pharmacological effect of vitamin E is that it is a powerful antioxidant. It is a fat-soluble substance that slows down the development of free radicals and thereby prevents the development of oxides that destroy cell membranes. Thanks to this, the normal functioning of the immune system is ensured and muscle tissue is strengthened. In addition, vitamin E prevents the destruction of red blood cells, and in combination with selenium slows down the oxidation of fatty acids.

Indications and dosage

Indications and contraindications for vitamin E are what drug buyers are primarily interested in. This vitamin should be supplied to the body with biological supplements if a person does not receive enough of it from food. Vitamin E deficiency is especially pronounced in newborns, as well as in children in the first years of life due to congenital or acquired diseases.

The body to fight the following diseases:

Necrotizing myopathy;
Cirrhosis;
Artresia of the biliary tract;
Crohn's disease;
Obstructive jaundice, etc.

In addition, a person needs increased doses of vitamin E after a gastrectomy, during pregnancy (especially when carrying multiple fetuses), during breastfeeding, and when a doctor prescribes a special diet. People who want to quit smoking or get rid of drug addiction should also take more vitamin E than others. Finally, taking vitamin E supplements is beneficial for all people to improve their health. However, it is important to observe the correct dosage, since an excess of vitamin E is harmful to the body.

According to accepted standards, the daily requirement for vitamin E ranges from 5-7 mg for young children to 14-15 mg for adolescents and pregnant women. A typical adult needs about 10 mg of the vitamin per day. To prevent hypovitaminosis, you cannot completely abandon medications with vitamin E, but its share should be below average. If complex treatment of diseases with vitamin E is required, the dosage is determined by the doctor individually for the patient.

Contraindications and side effects

The side effects of vitamin E have been well studied. Although they do not cause serious harm to the body, you should consult your doctor before taking vitamins. Contraindications to taking vitamin E are individual intolerance to drugs and hypothrombinemia - a bleeding disorder. It develops against the background of vitamin K deficiency and increases significantly with increasing concentrations of vitamin E in the body.

Allergic reactions and pain at the site of intramuscular injection are a possible side effect of vitamin E. An overdose of drugs is characterized by the following symptoms:

Dizziness and headache;
Nausea;
Increased fatigue, asthenia;
Diarrhea;
Weakened vision.

In more severe cases, an overdose of vitamin E leads to even more serious consequences:

Risk of bleeding due to poor blood clotting;
Thrombophlebitis;
Sepsis;
Kidney failure;
Hemorrhagic stroke;
Sexual disorders.

Interaction with other drugs

Vitamin E supplements enhance the effects of other substances, in particular antioxidants. They reduce the toxicity and enhance the benefits of taking vitamins A and D. However, with the increase, the level of vitamin A in the body may decrease, so you need to monitor the balance when taking supplements. In addition, vitamin E is used in conjunction with medications for epilepsy and cardiovascular diseases.

Mineral oils and some other compounds slow down the body's absorption of vitamin E. With a high concentration of iron in tissues, oxidative processes intensify, which leads to an increasing need for vitamin E in the body. Taking vitamin E in the treatment of skin diseases, hair loss, infertility, burns and a whole list of other diseases and pathologies is considered unreasonable. To ensure that medications are beneficial, you should always consult a doctor before taking them.