Betadine vaginal suppositories - instructions for use. Betadine solution Betadine iodine solution

100 ml of solution contains

active substance– povidone-iodine 10 g (which corresponds to active iodine 0.9 - 1.2 g),

excipients: glycerin 85%, nonoxynol 9, anhydrous citric acid, disodium hydrogen phosphate anhydrate, sodium hydroxide (10% solution (w/v) to establish pH), purified water.

Description

The solution is dark brown in color, with the odor of iodine, and does not contain suspended or precipitated particles.

Pharmacotherapeutic group

Antiseptics and disinfectants. Iodine preparations. Povidone-Iodine

ATX code D08AG02

Pharmacological properties

Pharmacokinetics

In healthy people, the absorption of iodine when the drug is applied topically is negligible. The absorption of povidone and its excretion by the kidneys depends on the average molecular weight of the mixture. For substances with a molecular weight above 35,000-50,000, a delay in the body is possible. When used intravaginally, the fate of absorbed iodine or iodide in the body is basically similar to the fate of iodine administered by any other route. The biological half-life is approximately 2 days. Iodine is excreted almost exclusively by the kidneys.

Pharmacodynamics

Povidone-iodine is a polymer complex of polyvinylpyrrolidone (povidone) with iodine. After application to the surface of the skin, iodine is released from this complex for some time. It has long been known that elemental iodine (I2) is a highly effective microbicidal substance capable of in vitro quickly destroy bacteria, viruses, fungi and some protozoa using two mechanisms: free iodine quickly kills microorganisms, and the PVP-iodine complex is an iodine depot. Upon contact with the skin and mucous membranes, an increasing amount of iodine dissociates from the complex with the polymer.

Free iodine reacts with oxidizable groups of SH- or OH- amino acid units of enzymes and structural proteins of microorganisms, inactivating and destroying these enzymes and proteins. In conditions in vitro most vegetative microorganisms are destroyed in 15-30 seconds. In this case, the iodine becomes discolored, and therefore the intensity of the brown color serves as an indicator of the effectiveness of the drug. After bleaching, the product can be reapplied. There have been no reports of development of resistance.

Indications for use

Disinfection of skin before biopsy, injections, punctures, blood collection and transfusion, infusion therapy

Antiseptic treatment of skin and mucous membranes, for example, before surgery, gynecological and obstetric procedures

Aseptic treatment of wounds

Bacterial and fungal skin infections

Complete or partial preoperative disinfection of the skin (preoperative disinfecting preparation of the patient, “disinfecting baths”)

Directions for use and doses

Betadine solution is intended for local external use.

Do not pour Betadine solution into hot water.

The solution should not be heated before use.

The solution should be prepared immediately before use and used as soon as possible.

Betadine solution can be used undiluted or after dilution with water as a 10% (1:10) or 1% (1:100) solution, depending on the area to be disinfected.

The drug should be left on the skin for 1-2 minutes before injection, blood draw, biopsy, blood transfusion, infusion therapy, or any other surgical procedure on intact skin.

For aseptic treatment of wounds, burns, for disinfection of mucous membranes, and for bacterial and fungal skin infections, use a 10% solution (dissolving Betadine with water in a ratio of 1:10).

For preoperative “disinfecting baths,” a 1% Betadine solution (1:100) is used. The entire surface of the body should be evenly treated with a 1% Betadine solution and after a 2-minute exposure, rinse the solution with warm water.

Betadine solution should be diluted immediately before use. The prepared solution cannot be stored.

Betadine solution can be easily removed with warm water. Difficult to remove stains should be treated with sodium thiosulfate solution.

When preoperatively disinfecting the skin, care must be taken to ensure that excess solution does not accumulate under the patient. Prolonged contact with the solution may cause skin irritation and, in rare cases, severe skin reactions. Accumulation of solution under the patient can cause a chemical burn.

Side effects

Rarely (≥1/10,000 -<1/1,000)

Increased sensitivity

Contact dermatitis (with symptoms such as erythema, small blisters on the skin, itching)

Very rarely

Anaphylactic reaction

Hyperthyroidism (sometimes accompanied by symptoms such as tachycardia and restlessness). In patients with a history of thyroid disease after use of povidone-iodine in significant quantities (for example, after long-term use of povidone-iodine solution for the treatment of wounds and burns on a large surface of the skin)

Angioedema

Frequency unknown (cannot be determined from available data):

Hypothyroidism (after using large amounts of povidone-iodine or after long-term use)

Electrolyte imbalance (possibly after use of povidone-iodine in significant quantities (for example, in the treatment of burns))

Metabolic acidosis**

Pneumonitis (complication associated with aspiration)

Acute renal failure**

Change in blood osmolarity**

Chemical burns of the skin may develop due to the accumulation of excess solution under the patient during preparation for surgery

** may develop after the use of povidone-iodine in significant quantities on large areas of skin or mucous membranes (for example, when treating burns)

Reports of suspected adverse reactions

Providing data on suspected adverse drug reactions is very important to enable continuous monitoring of the risk/benefit ratio of the drug. Health care professionals should provide information about any suspected adverse reactions to the contacts listed at the end of the instructions, as well as through the national reporting system.

Contraindications

Hypersensitivity to the active substance or other excipients

Hyperthyroidism

Other acute thyroid diseases

Dühring's dermatitis herpetiformis

Condition before and after the use of radioactive iodine in the treatment of the thyroid gland.

Drug interactions

The povidone-iodine complex is effective in the pH range 2.0 – 7.0. It is likely that the drug may react with proteins and other unsaturated organic complexes, which will lead to a deterioration in its effectiveness.

The combined use of Betadine and enzyme preparations for wound treatment leads to a mutual decrease in effectiveness. Medicines containing mercury, silver, hydrogen peroxide, and taurolidine may interact with povidone-iodine and should not be used at the same time.

The PVP-iodine complex is also incompatible with reducing agents, preparations containing alkali metal salts and substances that can react with acids.

Using povidone-iodine at the same time or immediately after using antiseptics containing octenidine on the same or adjacent areas of the skin may result in the formation of dark spots on the treated surface.

The oxidative effect of povidone-iodine can lead to false-positive results in various diagnostic tests (eg, hemoglobin and glucose measurements in feces and urine using toluidine and guaiac gums).

Absorption of iodine from povidone-iodine solution may alter the results of thyroid function tests.

The use of PVP-iodine may reduce the uptake of iodine by the thyroid gland, which may affect the results of some tests and procedures (thyroid scintigraphy, determination of protein-bound iodine, diagnostic procedures using radioactive iodine), and therefore planning the treatment of thyroid diseases with iodine preparations may become impossible. After stopping the use of PVP-iodine, a certain period of time should be maintained until the next scintigraphy is performed.

Special instructions

During preoperative preparation of the patient, it is necessary to ensure that excess solution does not accumulate under the patient. Prolonged contact with the solution may cause skin irritation and, in rare cases, severe skin reactions. Accumulation of solution under the patient can cause a chemical burn. In case of skin irritation, contact dermatitis or hypersensitivity, the drug should be discontinued.

The drug should not be heated before use.

Patients with goiter, thyroid nodules, and other non-acute thyroid diseases have an increased risk of developing hyperthyroidism when given large amounts of iodine. In this group of patients, in the absence of clear indications, the use of povidone-iodine solution for a long time and on large surfaces of the skin is unacceptable. Such patients should be monitored to identify early signs of hyperthyroidism and, if necessary, monitor thyroid function, even after discontinuation of the drug.

Betadine should not be used before or after radioiodine scintigraphy or radioiodine treatment for thyroid carcinoma.

When using the solution oropharyngally, avoid getting povidone-iodine into the respiratory tract, as this can cause pneumonitis. This is especially important in intubated patients.

The dark red color of the solution indicates its effectiveness. Discoloration of the solution indicates a deterioration in its antimicrobial properties. Degradation of the solution occurs in light and at temperatures above 40°C. Avoid contact of the drug with the eyes.

Use in pediatrics

Infants and young children are at increased risk of developing hypothyroidism when given large amounts of iodine. Since children of this age have increased sensitivity to iodine and increased skin permeability, the use of iodine PVP in children of this age group should be minimal. If necessary, thyroid function should be monitored (levels of T4 hormones and thyroid-stimulating hormone /TSH). Any possible oral exposure of povidone-iodine to children should be strictly avoided.

Betadine is one of the popular antiseptics used in surgery, gynecology, pediatrics and other areas of medicine. At what age can this medicine be used in children and what features of use are important for parents to know?

Release form

In the pharmacy assortment you can find the following Betadine:

A solution used for external treatment. This brown transparent liquid contains 10% of the active substance. The solution is poured into polyethylene bottles of different volumes - 30 ml, 120 ml and 1000 ml.
Ointment for external use. It is represented by a homogeneous mass of brown color, which has an indistinct odor of iodine. One tube contains 20 g of ointment with 10% active ingredient.
Vaginal suppositories. They are distinguished by their dark brown color, elongated shape and homogeneous structure. One package contains 7 or 14 suppositories.

Compound

The main ingredient in any form of Betadine is called povidone iodine. In 1 ml of solution and 1 gram of ointment it contains a dose of 100 mg. One suppository contains 200 mg of this substance.
Water, glycerol, sodium hydroxide solution and disodium hydrogen phosphate are added to the liquid form. In addition, citric acid and nonoxynol 9 are auxiliary components of the solution.
In addition to povidone-iodine, purified water and Na bicarbonate, Betadine ointment contains 4 types of macrogol (400, 1000, 1500 and 4000).
In candles, an additional component is macrogol 1000.

Operating principle

Betadine is classified as an antiseptic used locally and externally. Iodine, which is released from such a medicine upon contact with the mucous membrane or surface of the skin, combines with the proteins of the microbes, as a result of which the bacteria die within 15-60 seconds after treatment.

The drug has a bactericidal effect against many gram-positive and gram-negative microorganisms. The product also affects fungi, protozoa and viruses. Only tuberculous mycobacteria are resistant to it.

The principles of action of Betadine are very well shown in this video:

Indications

Betadine in solution is used for different purposes:

This drug is used to treat the patient’s skin during surgical treatment, both before and after surgery.
Betadine is used for various medical procedures, for example, with injections, punctures or biopsies. This solution is used to lubricate the skin around the probe, catheter or drainage.
Surgeons and other medical professionals apply this medicine to their hands before various procedures.
Betadine is recommended to treat the hands of people who care for an infected patient.
This drug is also in demand for processing patient care items.
The product is used topically for infections of the nasopharynx (drop into the nose), as well as the oral cavity (treated with stomatitis, used for gargling).
Betadine has been successfully used for various skin infections. It helps with viral infections (for example, chickenpox), fungal infections and purulent skin lesions.
Treatment with Betadine is prescribed for trophic ulcers, as well as for bedsores.

Betadine in the form of an ointment is in demand for purulent dermatitis, wounds, burns, trophic ulcers and other skin problems.

Betadine suppositories are prescribed for vaginosis, candidiasis, vaginitis and infection with Trichomonas, as well as for diagnostic or surgical manipulations in the vagina.

At what age is it allowed to take it?

Instructions for use of the ointment or solution prohibit treatment with Betadine in children during the neonatal period.

The use of the drug in the first 4 weeks of life is permissible only when absolutely necessary and only after tests to determine the condition of the thyroid gland.

Children older than a month can use these forms of medicine without fear, and in suppositories they are prescribed to girls over 8 years old.

Contraindications

Treatment with Betadine is prohibited:

In case of renal failure.
For thyroid adenoma.
With hypersensitivity to iodine.
For hyperthyroidism.
For dermatitis herpetiformis.

Side effects

If the patient has a hypersensitivity to iodine, treatment with Betadine will cause hyperemia, itching and other local symptoms, after which the drug should be discontinued immediately. To make sure there is no iodine intolerance, the first use of the medicine should be a trial - in a small amount on a small area of skin.

If Betadine is used in large quantities, treating a large area of skin or mucous membrane, iodine from the drug will be absorbed, which can worsen thyroid function. The same side effect can be observed with very long use of the medicine.

Instructions for use and dosage

Liquid Betadine is used according to the following recommendations:

To treat the skin with Betadine solution, it does not need to be diluted. For the treatment of mucous membranes, drainages, burn surfaces and in some other cases, the drug is diluted to a concentration of 0.1% to 5%.
Liquid Betadine should not be heated.
The medicine should not come into contact with the eyes.
If Betadine comes into contact with blood when treating wounds, this will reduce its bactericidal effect.
The drug should not be used for animal or insect bites.
The surface treated with Betadine turns brown due to the formation of a film from which iodine is released. When it disappears, the effect of the drug ends. If necessary, such a film can be easily removed with water.

Betadine ointment is gently applied to damaged skin. This dosage form is applied in a thin layer 2 to 3 times during the day. If required, you can cover the treated surface with an occlusive dressing on top. The ointment should not get on the mucous membrane of the eyes, and the skin after lubrication, as when treated with a solution, acquires a brown tint, which can be easily removed by rinsing with plain water.

The Betadine suppository should be moistened with water and carefully inserted into the vagina (this form is used especially carefully in virgins). The medicine is used at night for 7-14 days.

Overdose

With very severe poisoning, swelling of the larynx, deterioration of kidney and blood circulation, and pulmonary edema are possible. For treatment, the doctor prescribes symptomatic therapy.

Interaction with other drugs

Liquid Betadine should not be mixed with any disinfectants or antiseptics, especially if they contain enzymes, mercury or alkali. The same restriction applies to ointments.

Terms of sale

Purchasing any form of the drug at a pharmacy is available without a prescription. The average price of 30 ml of solution is 160-170 rubles, a tube of ointment is 240-250 rubles, and a package of 7 suppositories is 350-400 rubles.

Storage conditions and shelf life

For storage, you should choose an unlit, dry place where a small child does not have access. The liquid form should be stored at room temperature (below +30°C), the optimal temperature range for storing ointment is +15+25°C, and for storing suppositories – +5+15°C. The shelf life of the solution and ointment is 3 years, for suppositories - 5 years.

Betadine is an antiseptic and disinfectant drug for local and external use.

Released from the complex with polyvinylpyrrolidone upon contact with the skin and mucous membranes, iodine forms iodamines with bacterial cell proteins, coagulates them and causes the death of microorganisms.

On this page you will find all the information about Betadine: complete instructions for use for this drug, average prices in pharmacies, complete and incomplete analogues of the drug, as well as reviews of people who have already used Betadine. Would you like to leave your opinion? Please write in the comments.

Clinical and pharmacological group

Antiseptic.

Conditions for dispensing from pharmacies

Available without a prescription.

Prices

How much does Betadine cost? The average price in pharmacies is 450 rubles for suppositories, ointment costs 250 rubles, and the solution can be bought for 300 rubles.

Release form and composition

Betadine is available in the following dosage forms:

10% ointment for external use in aluminum tubes of 20 g, one tube in a cardboard box. 1 g of Betadine ointment contains 100 mg of povidone-iodine and auxiliary components (macrogol - 400, 1000 and 4000, sodium bicarbonate and purified water);
10% solution for local and external use in dropper bottles of 30 and 120 ml (in cardboard boxes) or 1000 ml (without box). The main active ingredient of the drug is povidone-iodine (100 mg in 1 ml of solution), and the auxiliary ingredients are glycerin, anhydrous citric acid, nonoxynol 9, sodium hydroxide 10%, disodium dihydrogen phosphate and purified water;
Vaginal suppositories are dark brown in color and torpedo-shaped. One suppository contains 200 mg of povidone-iodine and macrogol 1000 as an excipient. The candles are packed in blisters of 7 pieces, in a cardboard pack there are 1 or 2 blisters.

Pharmacological effect

The drug is a complex compound of iodine and polyvinylpyrrolidone (PVP). PVP, an inert synthetic polymer, acts as a carrier. Accordingly, all pharmacological properties of the drug are associated only with iodine, which belongs to the group of halogen antiseptics; The spectrum of action of iodine extends to gram-positive bacteria and gram-negative bacteria, fungi, protozoa, treponemes, viruses and acid-fast bacteria.

The bactericidal effect of iodine is explained by its strong oxidizing properties; it actively interacts with the amino acids of proteins, as a result of which the quaternary structure of the protein changes and its catalytic and enzymatic activity is lost. Basically, iodine disrupts the structures of bacterial transmembrane proteins and enzymes that do not have membrane protection. The concentration of active iodine in Betadine is 0.1-1%. Suppositories are made on a water-soluble basis and do not irritate the mucous membrane. When applied topically, there is almost no resorption of iodine from the mucous membrane.

Indications for use

Betadine suppositories are used in the following cases:

(as part of combination therapy);
fungal infections of the vagina resulting from treatment with steroid and antibacterial drugs;
chronic and acute vaginal infections of a specific and nonspecific nature (vaginitis, bacterial, etc.);
treatment before and after transvaginal interventions during obstetric and diagnostic procedures.

Betadine ointment has the following indications:

treatment of bacterial and fungal skin infections;
treatment of bedsores infected;
prevention of injury or infection of the skin (for small cuts and abrasions, minor burns and surgical interventions).

According to the instructions, Betadine solution is used in the following cases:

for disinfection of wounds and burns;
as first aid in case of contamination of mucous membranes or skin with infected material;
for antiseptic treatment of the operating room before gynecological, obstetric and surgical procedures and operations;
for disinfecting hands before taking a biopsy, performing punctures, injections, and catheterization of the bladder.

Contraindications

The use of this remedy is contraindicated for the following diseases and conditions:

subject to simultaneous use of radioactive iodine;
for a child under 1 year of age;
hyperthyroidism;
Dühring's dermatitis herpetiformis;
thyroid adenoma;
with high sensitivity to iodine, as well as to other components of this remedy.

The use of the medicine for newborns and premature babies is contraindicated. Use cautiously for chronic skin inflammations, during pregnancy, and also during lactation.

Instructions for candles

At acute vaginitis Prescribe 1 suppository 1-2 times a day for 7 days.
At chronic and subacute vaginitis– 1 suppository 1 time/day before bedtime for 14 days, if necessary – for a longer period.

Instructions for ointment

For external use only. Apply a thin layer of ointment to the affected skin surface 2-3 times a day. Can be used under occlusive dressings.

Instructions for the solution

To treat the skin and mucous membranes, a solution of Betadine is used undiluted for lubrication, rinsing, or as a wet compress.

For use in drainage systems, a 10% solution is diluted 10 to 100 times. The solution is prepared immediately before use; diluted solutions are not stored.

Side effects

The following side effects of suppositories and other forms of the drug are noted:

local manifestations of an allergic reaction to iodine in the form of redness, rash, itching;
vaginal dysbiosis (with prolonged use of suppositories);
thyrotoxicosis (with hereditary predisposition).

Overdose

In case of overdose, the following symptoms may be observed:

Dermatitis and redness of the skin.
Diarrhea.
Impaired renal function.
Intestinal disorders.
Metallic taste in the mouth.
Eye irritation and swelling.
Burning in mouth and throat.
Pulmonary edema.
Hypernatremia.

Special instructions

The use of Betadine may reduce the absorption of iodine by the thyroid gland and distort the results of diagnostic tests (thyroid scintigraphy, determination of protein-bound iodine, radioactive iodine measurements) or interfere with iodine therapy of the thyroid gland. After using the drug Betadine, before carrying out the listed procedures, you should wait a period, the duration of which should be determined by the doctor.
Long-term use of Betadine can lead to the absorption of significant amounts of iodine through the skin and mucous membranes. Therefore, after long-term use of suppositories, it is necessary to perform a thyroid function test.
The use of Betadine suppositories in childhood before reaching puberty is contraindicated. The doctor must decide on the possibility of using the drug in virgins and carry out at least the first administration of the suppository.
Povidone-iodine contamination may cause false-positive results in some diagnostic tests, such as detection of occult blood in the stool or glucose in the urine.
Accidental ingestion of suppositories by children should be avoided.

Drug interactions

It is forbidden to use Betadine vaginal suppositories together with other antiseptics: alcohol, salicylic acid, hydrogen peroxide, etc. This significantly increases the risk of getting a burn on the membranes of the genital organs, and the effectiveness of using both drugs decreases. The combined use of suppositories with drugs that contain taurolidine, silver, mercury, lithium and enzymes is unacceptable.

Content

There is a wide range of medications that have a disinfecting effect. These include Betadine solution - an antiseptic, which is used by gynecologists, surgeons and other doctors; the drug is successfully used for the treatment and prevention of many diseases. The main component of Betadine is iodine, so the product has a very wide spectrum of action aimed at combating bacteria, fungi and similar harmful organisms. According to reviews, the drug is distinguished by low toxicity, safety and high effectiveness of the drug.

Betadine solution - instructions for use

A special topical solution with an antiseptic effect is the drug Betadine. This medication combines iodine and its binder polyvinylpyrrolidone. The drug is also called povidone-iodine (non-proprietary international name). It has an antiviral, disinfectant, disinfectant, and bactericidal effect.

Composition and release form

The antiseptic medication is available in polyethylene bottles of 30, 120, 1000 ml. The kit includes a special dropper and a screw-on propylene plug with first opening control. Containers with the drug of 30 and 120 ml are packed in a cardboard pack, inside there are instructions for using the medicine. The 1000 ml bottle is not packaged in a separate package; an annotation plus two labels are simply attached to it. Betadine solution is a dark brown liquid with the odor of iodine.

Thanks to the composition of the drug Betadine, the maximum therapeutic effect is achieved. The product contains the following active and additional components:

Substance	Quantity (per 100 ml of product)
Active element povidone-iodine
Disodium hydrogen phosphate
Nonoxynol 9
Anhydrous citric acid
Glycerol
Sodium hydroxide solution	10% solution (w/o) to establish pH
Purified water	Rest volume

Mechanism of action of the drug

The disinfectant effect of using the drug Betadine is achieved with the help of iodine, which is released from the complex with polyvinylpyrrolidone. This occurs during contact with human mucous membranes and skin. Result: the active element interacts with oxidizable groups of amino acids that are part of the structure of enzymes of microorganisms and proteins. Effect of the drug: destruction of gram-positive, gram-negative microbes, some viruses, protozoa, spores and fungi.

After a long course of treatment of wounds and burns over large areas of the skin, an increased iodine content is observed in the body. The levels decrease to normal one to two weeks after the last use of povidone-iodine. It is excreted exclusively through the kidneys. In patients with a healthy thyroid gland, increasing the level of the active substance does not affect hormonal levels.

Indications for use

The medicinal antiseptic is sold without a prescription, but it can be taken only as indicated. Otherwise, you can aggravate the disease and worsen your overall health. The main pathologies for which Betadine is prescribed:

bedsores;
disinfection of skin for microdamages, ulcers;
diabetic foot;
household burns, wounds;
antiseptics of burns in traumatology and surgery;
bactericidal activity;
trophic ulcers;
disinfection of the skin area in which the catheter, probe or drainage system is installed;
therapy for bacterial, fungal, viral skin infections;
disinfection of the oral cavity in the presence of stomatitis and similar infections during dental surgery;
Betadine solution is used in dermatology to avoid the development of severe infection;
gynecology: treatment of mucous membranes before minor surgery (abortion, removal of erosion and polyps, insertion of an IUD);
obstetrics: antiseptics of a woman’s birth canal;
venereology: trichomoniasis, mycosis;
disinfection of parts of the mucous membranes and skin in preparation for surgery or installation of an IV.

Betadine for gargling

The drug is considered effective for infectious and viral infections affecting the throat and oral cavity of a person. For rinsing, an aqueous solution of iodine is used (ratio 1:10). Betadine is often used to treat the following diseases:

sore throat (tonsillitis);
pharyngitis;
laryngitis, etc.

Betadine for burns

The drug for external use has a disinfecting effect on the following skin lesions:

Treatment of small burns (10% solution).
Antiseptics of burn wounds.
Treatment of fire-damaged skin is carried out with 1%, 5% or 10% povidone-iodine, depending on the severity of the wounds.

During the treatment process, you need to be as careful as possible, since antiseptic treatment of large areas of severely damaged skin can lead to certain consequences:

negative reactions from electrolyte metabolism (increased amount of sodium in blood serum);
changes in osmolarity;
metabolic acidosis;
disorders of the kidneys.

Treatment of wounds

The medication Betadine is often used to treat various types of wounds on the skin:

bedsores;
abrasions, scratches;
cut wounds;
treatment of skin with ulcers;
superficial dermatoses;
prevention of infection in wound surfaces is carried out.

Directions for use and dosage

According to the instructions, the medicine can be used concentrated or mixed with water (it cannot be diluted with hot water). When treating burns, wounds, or preparing for surgery, the medicine is diluted with isotonic sodium chloride solution. You can warm the medicine in your hands to room temperature. The product is used no more than two or three times a day. Features of using Betadine:

Antiseptic for minor wounds, abrasions, scratches, small burns: 10% povidone-iodine undiluted twice a day.
Disinfection of the mucous membrane and surface of the skin before surgery: undiluted product twice in a couple of minutes.
Bactericidal effect against wounds, treatment of their complications: pure or 5% product 2-3 times a day.
Acne, ulcers on the skin should be treated with a cotton swab dipped in concentrated 5% or 10% povidone-iodine (1 part medicine and 2 parts water).
Burns are treated with 1%, 5% or 10% of the drug (1 part of the active substance to 10 parts of water), which depends on the severity of the damage.
According to doctors, to treat fungal or bacterial dermatitis, the skin should be treated with a 1% solution.
Disinfection before medical procedures (biopsy, blood sampling, infusion, puncture) is carried out using a concentrate for two minutes.
The consequences of invasions (drips) are eliminated with a 5% or 10% product.
Rinse the mouth and throat with a diluted solution twice a day.
Washing of serous and articular cavities is carried out once a day with 0.1% or 1% product.
To disinfect the skin of newborn children, a 0.1% solution is used, to treat the navel - 10%, to prevent conjunctivitis in babies - 2 drops of 2.5-5% medicine in each eye.
In transplantology and ophthalmology, 1% -5% medication is used.
Povidone-iodine is used once for hygienic disinfection of the birth canal, minor gynecological operations, and surgical treatment of cysts of parenchymal organs.
Herpes and papilloma are treated with a concentrated remedy. Hygienic treatment is performed twice a day.
Before surgery, the patient's body is wiped with a sponge soaked in Betadine (0.1-0.05%). Dilution of the solution: part 10% medicine, 100 and 200 parts water.

Special instructions

There are a number of special instructions that are specified in the instructions for the drug. If you do not adhere to them, side effects and complications of the pathology that is being treated may occur. Cautions and tips for using an antiseptic drug:

If a person has problems with the functioning of the thyroid gland, then the product can only be used under the supervision of a specialist.
Regular use of povidone iodine should be cautious when the patient has chronic renal failure.
After the drug dries, a colored film forms on the area of the skin or mucous membrane. This colored layer remains until all active iodine has left the body. When the film disappears, the drug ceases its effect.
Do not disinfect bites of domestic/wild animals or insects.
Areas of skin and tissue after treatment with Betadine have a dark brown color. Discoloration can be easily achieved with plain soap and water. If stains are difficult to remove, you can use an ammonia solution.
It is necessary to ensure that no excess solution remains under the bedridden patient, otherwise this will lead to severe skin irritation.
If the disinfectant gets inside, the stomach is washed with diluted sodium thiosulfate (5%).

Drug interactions

To avoid unpleasant side effects and not worsen your health, you need to be aware of the interactions of povidone-iodine with other medications. The instructions say the following:

Betadine is incompatible with medications containing mercury. This increases the risk of formation of alkaline mercury iodide.
The disinfectant may react with unsaturated organic compounds and proteins. This effect is compensated by increasing the dosage of povidone-iodine.
Patients being treated with lithium are advised to avoid prolonged therapy with the solution, especially on large affected areas.
The interaction of iodine with hydrogen peroxide, enzyme medications (containing tauloridine and silver) can cause a mutual decrease in the effectiveness of the drugs.

Betadine for children

The disinfectant has a slightly different effect on the skin of a baby than on the skin of an adult patient. Premature babies and newborns (especially in the first month of life) cannot be treated with an aseptic drug. The use of the medication is permitted only on the recommendation of a physician, and in the most extreme cases, after examining the thyroid gland.

Side effects

If the antiseptic is used incorrectly, unpleasant consequences may occur. When recommendations from the instructions are ignored, the following side effects are observed:

allergies (possible skin irritation, burning, itching, swelling, hyperemia);
hyperthyroidism is a chronic disease of the thyroid gland, which is characterized by an increase in the concentration of hormones in the blood (with long-term treatment with povidone-iodine);
serum osmolarity;
electrolyte imbalance;
renal failure;
An acute generalized reaction with hypotension and asthma attacks is rare.

Contraindications

Betadine has a number of contraindications that cannot be ignored. Otherwise, health problems cannot be avoided. Main restrictions:

thyroid adenoma;
period of breastfeeding, pregnancy (2nd and 3rd trimester);
hyperthyroidism;
hypersensitivity to active and additional elements of the drug;
Dühring's dermatitis herpetiformis.

Terms of sale and storage

Povidone-iodine is available in pharmacies without a prescription. The solution is stored in a dark, dry place at an air temperature of no more than 30 degrees above zero. The shelf life of the medicine is 3 years.

Betadine analogue

In pharmacy kiosks you can find an assortment of analogues of the disinfectant drug. The most popular and effective means are:

Povidone-Iodine;
Iodixol;
Iodinol;
Octasept;
Iodoflex;
Bethiod.

Betadine price

You can purchase a broad-spectrum antiseptic at any pharmacy in Moscow and the region. The cost of the medicine depends on the manufacturer, the form of release and the specific place of sale. Below is a table with the average approximate price for a disinfectant in different pharmacies across the country.

Video

Antiseptics - halogens and halogen-containing ones.

Composition of Betadine

The active substance is povidone-iodine.

Manufacturers

Egis Pharmaceutical Works SA (Hungary), Egis Pharmaceutical Plant (Hungary)

Pharmacological action

Antiseptic, disinfectant.

It has a wide spectrum of antimicrobial action (gram-positive and gram-negative bacteria - with the exception of M/ tuberculosis, fungi, viruses, protozoa).

It has a longer action than inorganic iodine solution.

Suppositories are made on a water-soluble basis and do not have an irritating effect.

When applied topically, there is virtually no absorption of iodine from the skin, mucous membrane or wounds.

Side effects of Betadine

When used on a large wound surface and mucous membranes, systemic reabsorption of iodine may occur, which may affect thyroid function tests and also lead to the development of neutropenia.

In some cases, with hypersensitivity to the drug, local manifestations of allergic reactions to iodine (hyperemia, burning, itching, swelling, pain) may occur, requiring discontinuation of the drug.

Long-term use (more than 7-10 days) can cause the phenomenon of iodism (a “metallic” taste in the mouth, increased salivation, swelling of the eyes or larynx, etc.), if this occurs, you should stop using the drug and consult a doctor.

Indications for use

Solution for external use 10%.

Treatment and prevention of wound infections in surgery, traumatology, combustiology, dentistry.

Treatment of bacterial, fungal and viral skin infections, prevention of superinfection in dermatological practice.

Treatment of bedsores, trophic ulcers, diabetic foot.

Disinfection of the skin and mucous membranes of patients in preparation for surgical interventions, invasive studies (punctures, biopsies, injections, etc.) Disinfection of the skin around catheters, drainages, probes.

Disinfection of the oral cavity during dental operations.

Disinfection of the birth canal during “minor” gynecological operations (artificial termination of pregnancy, insertion of an intrauterine device, coagulation of erosion or polyp, etc.).

Foaming solution 7.5% for external use. "Disinfectant bathing" for complete or partial treatment of patients before surgery.

Disinfection of the skin of the hands of surgical personnel.

Hygienic treatment of patients.

Hygienic treatment of hands when in contact with infected patients.

Processing of non-metallic instruments and patient care items.

Concentrate for preparing a solution for topical use.

Inflammatory processes in the mouth and throat.

Condition after surgical interventions in the mouth and throat.

Eliminating bad breath.

Bacterial and fungal skin infections, burns, trophic ulcers, bedsores, infectious dermatitis, abrasions, wounds.

Vaginal suppositories.

Treatment of vaginitis (mixed, nonspecific), candidiasis, trichomoniasis, genital herpes; preoperative preparation.

Contraindications Betadine

Hypersensitivity, thyroid adenoma, hyperthyroidism, Dühring's dermatitis herpetiformis, chronic renal failure, simultaneous use of radioactive iodine, pregnancy, lactation, children under 8 years of age.

Directions for use and dosage

1 suppository 1-2 times a day; Duration of treatment is 7-14 days.

Overdose

No information available.

Interaction

Incompatible with other disinfectants and antiseptics, especially those containing alkalis, enzymes and mercury.

Activity decreases in an acidic environment.

Special instructions

Solution 10%, foaming solution 7.5%.

It is necessary to ensure that no excess solution remains under the patient.

Should not be heated before use.

Concentrate 8.5% for preparing a solution for topical use.

It has a deodorizing effect - it eliminates bad breath that occurs after eating food, alcoholic beverages, and tobacco.

Solutions 10, 7.5%; concentrate 8.5%; ointment 10%.

The presence of pus and blood can reduce the antimicrobial effect of the drug.

A colored film is formed at the site of application, which persists until the entire amount of active iodine is released, which means that the effect of the drug ceases.

Should not be used for bites from insects, domestic or wild animals.

All dosage forms.

Coloring on leather and fabrics is easily washed off with water.

Avoid contact of the drug with the eyes.