“Meloxicam is an effective and safe selective NSAID.” Meloxicam reviews Meloxicam interactions with other drugs

Meloxicam is a drug belonging to the category of non-steroidal anti-inflammatory drugs. The medicine has the following properties: reduces fever, produces an analgesic effect, and is used as an analgesic. Used for the symptomatic treatment of joint diseases. These include arthritis, osteoarthritis and arthrosis.

Composition and release form

Different varieties of Meloxicam (C3, Sandoz, Pfizer, Prana, etc.) are the same drug. The drugs differ from each other only in names. All of the listed medications are available in equal dosage forms with the same dosages of active ingredients.

Various varieties of the drug, analogues of Meloxicam, appeared due to the fact that each manufacturer decided to register its own medicine as a separate trademark.

All types of medicine are available in several varieties:

Tablets prescribed for oral use – 7.5 mg and 15 mg.
Solution intended for injection – 10 mg/ml.
Rectal suppositories – 15 mg.

Composition of the product

The active ingredient is Meloxicam in different doses. The drug itself is called the active substance.

Tablets and suppositories include the following auxiliary components:

Starch;
Magnesium stearate;
Sodium citrate dihydrate.

The following auxiliary components are added to injection solutions:

Megyumin;
Glycine;
Sodium chloride;
Water;
Sodium hydroxide.

Pharmacological action

Meloxicam is classified as a drug classified as an NSAID and produces the following effects:

Relieves inflammation.
Has an analgesic effect.
Reduces fever in diseases and conditions caused by inflammatory processes.

These effects were achieved by slowing down the operation of cyclohexanes. Cyclohesan is an enzyme that provides the formation of two active substances: leukotrienes and prostaglandins. They are substances that ensure the onset and further maintenance of the inflammatory process in each organ, regardless of the cause. The cause may be injury or infection causing inflammation.

Taking the medication Meloxicam stops the production of prostaglandins and leukotrienes. This causes the inflammation to subside naturally because the biological components needed to support it are not present. The product is an effective anti-inflammatory process.

Each inflammatory process (the cause of its occurrence does not matter) is characterized by the following five signs:

The appearance of redness;
Swelling;
Painful sensations;
Temperature;
Functions are impaired.

All these inherent characteristics are stopped by Meloxicam. This drug relieves inflammation, eliminates pain and redness. The main distinguishing feature is the ability of the drug to act exclusively on one modification of cyclooxygenases called COX-2.

Indications for use of Meloxicam

Rheumatoid arthritis;
Osteoarthritis;
Ankylosing spondylitis;
Other inflammatory diseases with pain symptoms.

The instructions note that the drug Meloxicam is intended for the treatment of the listed diseases, as it relieves pain, swelling and reduces the severity of the inflammatory process. Thanks to taking the drug, movement in the affected joint is facilitated. However, the drug cannot be considered the main remedy, since it relieves symptoms but does not affect the course of the disease. To prevent the disease from progressing over time, it is imperative to include in therapy drugs that affect the causes of development.

Contraindications

Previous bleeding in the gastrointestinal tract.
Kidney and liver failure in severe forms.
Pregnancy;
Feeding a baby with breast milk.
Excess potassium in the blood.
Individual intolerance to the components included in the product.
Inflammatory diseases of the rectum.

The listed contraindications for Meloxicam apply to tablets, suppositories and solution. However, injections have other contraindications, which you also need to familiarize yourself with:

Development of asthma.
Simultaneous use of anticoagulants (for example, warfarin).
Kidney disease that progresses over time.
Heart failure.
Pain after bypass surgery.

Side effects

Before taking the medicine, you should carefully read the possible side effects:

Nervous system:

The appearance of dizziness;
Headache;
Consciousness becomes confused;
Mood swings;
A person suffers from insomnia.

Visual organs:

Seeing double;
Visual acuity deteriorates;
Conjunctivitis.

Auditory organs:

Ringing in ears;
Vertigo.

Circulatory system:

Anemia;
The number of leukocytes in the blood decreases;
There are no basophils in the blood.

Heart and blood vessels:

Heartbeat increases;
Blood pressure increases;
Flushes of blood.

Nausea with vomiting;
Belching after taking the product;
Pain in the abdominal area;
Diarrhea, flatulence, etc.;
Gastritis;
Gastric and duodenal ulcers;
Hepatitis.

Urinary system:

The occurrence of difficulties associated with urination;
Acute urinary retention;
Nephritis;
Nephrotic syndrome;
Kidney failure.

Skin tissue:

The appearance of itching;
Rash;
Dermatitis after taking the product;
Necrolysis;
Erythema.

Allergy:

Hives;
Rash;

Other side effects:

The appearance of a cough;
Swelling;
Asthma attacks;
In rare cases, fever.

Instructions for use

Method and dosage of tablets

Meloxicam tablets must be taken orally during meals. They must be swallowed whole and should not be broken or chewed. According to the instructions, you need to take the drug with a small amount of liquid. It will be enough to drink half a glass. Tablets can be taken before meals, but then the likelihood of side effects increases. To reduce this risk to a minimum, it is recommended to take Meloxicam with food.

According to the instructions, the dose is selected individually for each patient. The selection takes into account the severity of the disease, the initial condition, and the body’s response to the therapy.

For various diseases, the following dosages are prescribed:

For rheumatoid arthritis, 15 milligrams per day is prescribed. If persistent remission occurs after treatment, the dosage is reduced to 7.5 mg;
For osteoarthritis, 7 milligrams are prescribed once a day. If this dosage of the drug does not relieve pain and does not prevent inflammation, then it is increased to 15 milligrams;
For anclosing spondyloarthritis, the doctor prescribes 15 milligrams per day;
For other inflammatory diseases, you need to take 7 mg once a day.

According to the instructions, the maximum daily dosage of the drug is 15 mg. If the patient is over sixty-five years old and suffers from severe renal failure, then the dosage is 7.5 mg.

Method and dosage of injections

Meloxicam injection solution contained in ampoules is ready for use and does not require further dilution. It is necessary to draw the injection into a syringe and inject intramuscularly. The solution contains 10 mg/ml of the main substance. Since the ampoule contains 1.5 ml of solution, the ampoule contains 15 mg of the active component. This must be taken into account when calculating the dosage.

Meloxicam injection solution is intended for intramuscular use. Intravenous administration of the drug is prohibited. This is due to the likelihood of allergic reactions and inflammation of the vein walls with thrombosis. It is recommended to inject the solution into the upper lateral square of the buttock, since a special muscle layer is located in this area of the body. After administration, the solution in it is deposited, so it will slowly enter the blood. This is the reason for the long-term effects of the drug Meloxicam. To find this injection site, you need to divide the buttock into four parts. The upper square, located on the outside, is the most optimal area.

If it is prohibited to inject into the buttock area, then the solution must be injected into a third of the surface of the thigh. Before performing the injection, you must thoroughly wipe the area with a cotton swab soaked in an antiseptic solution. To do this, you can take alcohol or Belacept. Then you need to draw the solution into the syringe, turn it upside down with the needle, and tap the wall a little so that the bubbles appear on the surface of the liquid. Next, you need to press the plunger to release a few drops of the product. Only after these procedures can the solution be administered intramuscularly.

Dosage of solution administration:

For osteoarthritis - 7.5 mg of Meloxicam (half of one ampoule) once a day for five days. Then you need to take pills. If after the first injection of the solution there is no improvement in the condition, then the dosage is increased to 15 mg.
Rheumatoid arthritis must be administered 15 mg once a day for five days.
For ankylosing spondylitis, 15 mg is administered once a day for five days.
For other inflammatory diseases, it is necessary to administer 7.5 milligrams once a day for seven days.

For patients over 65 years of age, for various diseases, it is necessary to administer 7.5 milligrams of the drug once a day for five days. If a person suffers from renal failure, but the creatinine clearance is 5 ml/minute, then the drug must be taken in a standard dosage. It is necessary to reduce the dose if creatinine clearance is less than 5 ml/minute.

Meloxicam for children

Meloxicam should not be taken by patients under fifteen years of age. Otherwise, this may cause undesirable consequences and many side effects of use. From the age of fifteen, the dosage of the medicine is determined independently by the attending physician. If possible, the drug is replaced with a similar drug until the patient turns eighteen years old.

During pregnancy and lactation

During pregnancy, as well as breastfeeding, doctors do not recommend taking Meloxicam. In high dosages, this drug causes a teratogenic effect, which can cause fetal deformity or death. Fetal death can occur if Meloxicam is taken in a dose of more than five mg per kilogram of weight.

Despite the fact that the therapeutic dosage of Meloxicam for use is significantly lower than that which can cause deformity or death of the fetus, pregnant mothers should not take it, since it is not known for sure what this can lead to. In exceptional cases, a woman may need this medicine. Meloxicam can be taken only in the first two trimesters of pregnancy under the condition that the benefits of use cover the potential risks to the fetus.

In the third trimester of pregnancy, it is prohibited to take Meloxicam:

The drug may cause post-term pregnancy;
Possibility of prolonged labor;
High probability of birth complications: the cervix is poorly dilated, etc.

Special instructions

In full accordance with the instructions, the duration of the therapeutic course is determined individually for each patient. It depends on the severity of the disease and the persistence of the remission stage. The course of administration for chronic diseases is from four to eight weeks, for acute conditions the duration is about three weeks.

The general rule according to which the duration of use of the drug Meloxicam is determined is to focus on the patient’s well-being and the condition of his joints. In other words, treatment with the drug will continue until the pain is relieved and the joint is restored. If the need arises, Meloxicam courses can be repeated.

Interaction with other drugs

Meloxicam interacts with such drugs and causes the following consequences:

When taken with NSAID medications (Paracetomol, Indomethacin, etc.), the likelihood of an ulcer appearing in the digestive tract increases.
With indirect anticoagulants (Warfarin, etc.), heparin and thrombolytic agents (Alteplase, Urokinase, etc.), the likelihood of bleeding from the gastrodigestive tract increases.
With medications that have a diuretic effect, the risk of developing renal failure and increased blood pressure increases.
When taken with lithium salts, the lithium content in the blood increases, which is harmful due to its toxicity.
If medications intended to lower blood pressure are used at the same time, their effect is reduced.

Domestic and foreign analogues

Similar drugs that have a similar spectrum of action with Meloxicam:

Zornica in tablet form;
Meloxicam analogue - Piroxicam in the form of tablets and capsules for oral administration;
Tenoxtil in capsule form;
An analogue of the drug is Pyroxyfer in capsule form.

Price in pharmacies

The price of Meloxicam in different pharmacies may vary significantly. This is due to the use of cheaper components and the pricing policy of the pharmacy chain.

Read the official information about the drug Meloxicam, the instructions for use of which include general information and a treatment regimen. The text is provided for informational purposes only and cannot serve as a substitute for medical advice.

Meloxicam is used to reduce pain in the spine and joints. It has a strong anti-inflammatory effect, which makes the medicine indispensable for many patients.

Meloxicam - description and action

The drug Meloxicam Available in solution for injections (in ampoules), tablets, suppositories. It belongs to the group of nonsteroidal anti-inflammatory drugs (NSAIDs) and has analgesic, anti-inflammatory, antipyretic, and anti-edematous effects. The active substance is meloxicam, a derivative of enolic acid.

The additional composition of the medicine in the form of a solution is as follows:

saline;
sodium hydroxide;
ethanol;
poloxamer.

The price for a package of 3 ampoules is 160 rubles. The cost of tablets of the same name in pharmacies is 180 rubles (10 pieces). There are also suppositories on sale, the price for 5 pieces is 250 rubles. In the prescription for the drug, doctors indicate the Latin name - for example, tab. Meloxicam.

The principle of action of the drug is to selectively suppress the enzyme COX-2, thereby preventing the formation of inflammatory mediators - prostaglandins.

The difference with drugs of the same group, but of previous generations, is significant. Meloxicam helps reduce or stop pain, and does not lead to the development of erosions, gastritis, or intestinal lesions, which turns out to be much more effective. The drug has good compatibility with biological processes in the body, side effects are less common, so it can be used in longer courses (in this case it has the most pronounced effect).

Indications for use

It is better to use the drug only as prescribed by a doctor, especially when it comes to undergoing a course of therapy. It is recommended, for the most part, for inflammatory, degenerative, destructive pathologies of bones, ligaments, vertebrae, and bone joints.

Meloxicam is indicated for the relief of pain and inflammation during exacerbation of rheumatoid arthritis, for this purpose it is recommended for long-term use. It helps reduce painful symptoms in other types of arthritis:

Meloxicam is prescribed for short-term relief of a complex of symptoms of osteoarthritis of the joints, especially the knee, elbow, and ankle. Among the pathologies of the spine, the drug helps against osteochondrosis, hernias and protrusions. Also, indications for the use of Meloxicam include:

The form of the drug for each specific case is selected by a specialist; usually the choice depends on the strength of the pain syndrome and the severity of the disease.

Instructions for use

The tablets are taken orally, preferably with meals. It is allowed to take the medicine immediately after meals. Take the product with a sufficient amount of liquid, preferably water. The order of taking the tablets is described below:

dose per day - 7.5-15 mg (half a tablet or a whole tablet);
in case of renal failure, the dose of 7.5 g/day should not be exceeded; the same amount is indicated for elderly patients;
number of appointments/day - one;
Children over 15 years of age are prescribed the maximum amount of medication/day - 0.25 mg/kg body weight.

In rheumatoid arthritis it is possible drink 15 mg once a day, and after achieving a stable result, reduce the dose. For osteoarthritis, on the contrary, they first take 7.5 mg/day, and if necessary, increase the dose. Course - 3-15 days.

The risk of “side effects” is higher with a high dose and long-term use, so you should select the smallest amount of the drug that has a positive effect.

Meloxicam solution is administered once a day, usually therapy in the form of intramuscular injections does not exceed 3 days. In patients with renal failure, the ampoule is divided in half. Suppositories are administered rectally once a day (15 mg of the drug).

How to give injections correctly?

The therapeutic effect of Meloxicam directly depends on the route of entry into the plasma. If the drug is distributed in the body through intramuscular injection, positive dynamics appear after the first injection. In patients with severe joint pathology, pain relief occurs after 40-60 minutes and increases after subsequent administration for 72 hours. Pharmacological activity is manifested in skeletal and smooth muscle structures, articular-cartilaginous tissues, but the high absorption of β-synovial fluid is of particular importance for interstitial administration (C max 7 hours after the injection or C max after 5-7 days of oral tablets).

Meloxicam injections are prescribed intramuscularly once a day, at a dosage of 7.5-15 mg. A single administration is due to a long half-life cycle of the main active substance (20-24 hours). For the treatment of spontaneous pain and pain during movement, a standard stepwise scheme is recommended:

3 injections at a dosage of 7.5-15 mg for 3 days (1 injection per day);
tablets in a dosage of 7.5-15 mg 1 time per day, for a course of 3 days.

Taking Meloxicam intramuscularly more than 3 times is not recommended to avoid internal bleeding and other side effects that can be caused by NSAIDs. If the pain syndrome is of mild intensity, tablets are not included in the therapeutic plan.

Side effects and contraindications

Among the undesirable effects, gastrointestinal pathologies occupy first place, although serious diseases (gastritis, ulcers, erosive lesions of the mucous membrane) usually do not occur if the dosage frequency is observed and in short courses. The most commonly observed phenomena are:

nausea;
flatulence;
diarrhea;
decreased appetite;
constipation;
digestive disorders.

Gastrointestinal bleeding is rare, they usually appear in people with existing stomach ulcers. The heart and blood vessels can also give unpleasant side symptoms - a moderate increase in blood pressure, arrhythmias, swelling, heat in the face and chest. Typically, such phenomena disappear after discontinuation of the drug.

Meloxicam occasionally exhibits the following side effects:

When the solution is injected into the muscle, painful papules and swelling sometimes appear at the injection site. Allergic reactions with this form of use are more common than when taking tablets.

The instructions list bronchial asthma, erosions and ulcers of the gastrointestinal tract, Crohn's disease, ulcerative colitis, severe organ failure, age under 15 years for tablets, under 18 years for injections, pregnancy, lactation as contraindications to treatment.

Analogs and other information

Among the analogues are many drugs from the NSAID group, which are presented in pharmacies.

The drug combines well with muscle relaxants (,), and therefore is often prescribed together with them for the treatment of joint, muscle, and vertebrological pathologies.

The therapeutic effect of the analogues, which are available in the form of a solution for intramuscular administration, is the ability to suppress inflammation localized in muscle and joint tissues, as well as relieve syndromes associated with the activity of the inflammatory process. Tablet forms of NSAIDs also have a similar effect, including:

tablets Ibuprofen, Nimesulide, Arcoxia, Airtal;
ointments and gels for external use Voltaren, Diclofenac, Nise gel.

The pharmacological action of oral and local agents is aimed at inhibiting the synthesis of prostaglandins - inflammatory mediators that stimulate pain and fever.

Comparison of Meloxicam and Movalis

Since a doctor or pharmacist often offers a choice of Meloxicam or Movalis, which is more effective and which drug to give preference remains a subject of open debate. The differences in these products are practically invisible, since the main active ingredient in them is meloxicam. The difference between drugs lies in the manufacturer and brand.

The pharmacology and composition of Movalis and Meloxicam injections are completely identical.

The pioneer of the line is the substance meloxicam, which was first synthesized by the German company Boehringer Ingelheim. The company launched it on the market as part of the drug Movalis in 1995.

A line of drugs under the trade name Meloxicam is produced by analogy with the original drug in many countries - among the drug manufacturers are Teva Israel, Hemofarm Serbia, Vertex Russia, etc.

Which is better - Xefocam or Meloxicam?

There are two drugs in the oxicam line that are most often prescribed for the treatment of inflammatory and degenerative pathologies of joint tissue - Xefocam or Meloxicam, which are better and more effective than other NSAIDs. These medications have a number of differences that need to be taken into account when choosing:

the main component of Xefocam is lornoxicam, with high analgesic activity and a short half-life;
in Meloxicam, the active properties are exhibited by the active substance of the same name, meloxicam, with a high clinical safety profile.

A distinctive feature of meloxicam is its balanced effect on cyclooxygenase isoenzymes, which makes it the drug of first choice. During a course of treatment, this oxicam poses virtually no danger to the gastrointestinal tract and provokes negative changes only with long-term use (over 6 months). The advantage of lornoxicam is the stimulation of the production of endogenous opiates. The average dosage of Xefocam (8 mg lyophilisate once) can replace the average dose of opioid analgesics.

The main advantage of Meloxicam is the selective inhibition of the prostanoid PGE 2 C 1. This substance is a catalyst for PGE 2 - prostaglandin, which activates kinins (mediators of pain and hyperthermia). Unlike other NSAIDs that indirectly suppress the synthesis of PG, meloxicam blocks the synthesis of this prostanoid and does not affect COX 1. Inertness towards the first type of cyclooxygenase reduces its toxicity to the gastrointestinal tract.

You should not take alcohol in parallel with the medicine - this increases the risk of bleeding and organ failure. In case of overdose, side effects become more pronounced; the stomach should be rinsed and symptomatic treatment performed.

Instructions for use of Meloxicam (INN) are described in detail in the drug leaflet. However, before you start taking it, you must be sure to familiarize yourself with the composition of the medicine, since some of its components can provoke allergic reactions, as well as study contraindications and side effects that may appear during treatment.

Composition, release form

Before telling why Meloxicam is prescribed and how long to take it, you need to consider its composition. The active ingredient is meloxicam, which has anti-inflammatory, antipyretic and analgesic effects.

The medicine has several forms of release:

tablets for oral administration – 7.5 mg and 1.5 mg;
solution for injection – 10 mg/ml;
rectal suppositories – 15 mg.

In addition to the main active ingredient, Meloxicam tablets contain:

magnesium stearate;
colloidal silicon dioxide;
potato starch;
lactose monohydrate.

Solution for injection contains:

megumin;
sodium hydroxide;
sodium chloride;
glycine;
glycofurol;
water for injections.

In addition to meloxicam, rectal suppositories contain solid fats - the amount is sufficient to produce suppositories weighing 1.25 mg.

Pharmacological properties

Speaking about what Meloxicam helps with, one cannot fail to mention its pharmacological properties. Some people wonder - what is it, an antibiotic or not? No, this medication does not belong to the category of antibacterial drugs. It is a non-steroidal anti-inflammatory drug (NSAID). Its main task is to relieve pain, relieve inflammatory reactions, and normalize body thermoregulation.

This effect is explained by the fact that the active substance can slow down the work of cyclooxygenase. This is an enzyme that stimulates the synthesis of several biologically active substances in the body - prostaglandins and leukotrienes. They are the ones who provoke the occurrence of inflammatory processes in tissues and organs, regardless of the reason that led to such a reaction.

Simply put, there is some kind of provoking factor affecting the body that causes inflammation, for example, some kind of infection or injury. This stimulates the active work of cyclooxygenase and the subsequent synthesis of leukotrienes and prostaglandins, which support inflammatory reactions at the cellular level. When taking Meloxicam, the activity of these substances slows down, and accordingly, the inflammation begins to gradually subside completely or partially.

Any inflammation, regardless of etiology and location, causes:

redness;
swelling;
painful sensations;
violation of thermoregulation (either the general body temperature rises or the local one - the skin at the site of the pathological process becomes hot to the touch);
functional disorders.

Functional disorders consist in the fact that during inflammatory reactions a person cannot perform actions in full in the part of the body where the pathological process is noted. And since pain, fever, swelling and redness are signs of inflammatory reactions, taking Meloxicam, having an anti-inflammatory effect, also helps eliminate other unpleasant symptoms.

It should be noted that the drug has a strong analgesic and antipyretic effect. But it has little effect on swelling and redness. Therefore, its use allows you to quickly get rid of pain and fever, while other signs of inflammatory reactions go away slowly.

Indications

Why is Meloxicam prescribed? The main indications for use are diseases characterized by inflammatory processes in joints, muscles and bone tissue. In tablet form, this medicine is recommended to be taken for:

rheumatoid arthritis;
osteoarthritis;
Bekhterev's disease;
inflammatory or degenerative diseases of the joints (polyarthritis, reactive arthritis, etc.), accompanied by severe pain.

Rectal suppositories and injection solution have the same indications. The only difference is their use for osteochondrosis of the back. If a person experiences pathological changes in the thoracic or cervical region, it is recommended to use Meloxicam tablets or injections. Candles can be used for osteochondrosis of the lumbar spine. In this case, injections will also help well.

You can use the drug only after prior consultation with your doctor.

Contraindications

Before you start using Meloxicam, you need not only to familiarize yourself with its indications for use, but also carefully study the contraindications. These include the following conditions:

intolerance to the active or excipients of the drug;
decompensated heart failure;
recovery period after coronary artery bypass surgery;
ulcerative lesions of the duodenum, stomach;
gastrointestinal bleeding;
ulcerative colitis, Crohn's disease;
liver pathologies in the active phase;
renal pathologies;
pregnancy;
breastfeeding;
age up to 12 years.

Meloxicam tablets contain lactose, so persons suffering from lactose intolerance/deficiency or glucose-galactose malabsorption should not take the product.

The medicine is prescribed with caution for (in these cases, the use is strictly controlled by a doctor):

coronary heart disease;
cerebrovascular diseases;
congestive heart failure;
diabetes mellitus;
pathologies of peripheral arteries;
the patient has nicotine or alcohol addiction;
old age;
severe somatic diseases.

Meloxicam should also be taken with caution in combination with drugs such as:

anticoagulants;
antiplatelet agents;
glucocorticosteroids;
SSRIs.

ADVICE . To avoid negative consequences from the gastrointestinal tract, when taking the above drugs, it is necessary to use the minimum dosage of Meloxicam.

Instructions for use

We figured out what Meloxicam helps with. Now we need to consider how to properly use and dose the product. And since it has different forms of release, it is used in different ways.

Injections

The solution is now ready for administration. It does not need to be diluted. The drug is injected exclusively into the gluteal muscle. The drug is not used for intravenous administration, as it can provoke inflammatory processes in the venous walls with subsequent formation of thrombosis and embolism.

Rules for administering intramuscular injections

When giving injections, you need to know in advance to determine the area where the drug will be administered. It is optimal to administer an injection into the upper lateral square of the gluteal muscle (to determine it, the butt is visually divided into 4 parts by vertical and horizontal lines), since the muscles are most developed in this area. Once in them, the solution stays in the tissues longer and its absorption into the blood slows down, which makes it possible to achieve the longest therapeutic effect. If for some reason it is impossible to give an injection in the gluteal region, then the drug is injected into the upper third of the anterior lateral surface of the thigh.

The duration of use of Meloxicam in injections is no more than 5 days. After this, the drug is started to be taken in tablet form. The dosage of injections is determined by the attending physician individually, depending on the severity and speed of the pathological process.

Instructions for use of Meloxicam indicate the standard scheme for using the solution. For osteoarthritis, the drug is administered intramuscularly in a minimum dosage of 7.5 mg. Administration is carried out once a day, no more than 5 days. If after the first injection the patient’s condition remains unchanged, the next time the dosage is increased to 15 mg. After 5 days of injection therapy, they switch to taking the drug in tablets.

Exceeding dosages may cause adverse reactions and serious gastrointestinal complications.

If a person has rheumatoid arthritis, Meloxicam is administered intramuscularly at 15 mg, which corresponds to 1 ampoule, 1 time per day. Treatment is also carried out for no more than 5 days. The same dosage is used in the case of ankylosing spondylitis.

When identifying other inflammatory and degenerative joint diseases, 7.5 mg of the drug is used once a day. If treatment is carried out in elderly people, a dosage of 7.5 mg (1/2 ampoule) is used under any circumstances.

It is necessary to understand that the above describes the standard regimen for using Meloxicam, which is presented by the manufacturer of the drug. The dosage can be adjusted by the doctor depending on the severity of the pathological process.

Pills

Meloxicam tablets should be taken with meals. They cannot be chewed or dissolved. Must be swallowed whole. Drink only plain water. If you take them before or after meals, this will increase the risk of adverse reactions from the gastrointestinal tract. Just as with injections, the dosage is determined individually. The instructions include a classic treatment regimen.

In the case of osteoporosis and other inflammatory and degenerative diseases, the minimum dose is used - 7.5 mg (1/2 tablet). If positive results are not observed within several days of treatment, the dosage is doubled to 15 mg. The drug is also taken once a day.

How many days can the drug be used? The standard course of treatment with Meloxicam for acute pathologies is 1-3 weeks, for chronic pathologies it increases to 8 weeks (the medicine is taken without interruption). Then it is repeated several times a year to avoid exacerbations.

Rectal suppositories

Meloxicam rectal suppositories are inserted into the rectum. Suppositories act much faster than tablets, since the active substances are better absorbed into the blood through the mucous membranes of the intestines. Simply put, the therapeutic effect from suppositories is the same in terms of onset as from injections. And if a person is experiencing severe pain, but there is no way to give an injection, you can insert a suppository into the rectum.

However, it is not recommended to use suppositories for a long time, as this can cause intestinal problems, cause constipation or the formation of ulcers.

Rectal suppositories are available in two versions - 7.5 mg of active ingredient and 15 mg. The instructions say that for any condition it is necessary to use 15 mg of the drug per day. That is, you can administer a single suppository containing 15 mg of the active substance or 7.5 mg 2 times a day.

To ensure better absorption of the drug, you must have a bowel movement before administering the suppository. It is strictly forbidden to use this form of Meloxicam for:

inflammation of the rectum;
intestinal bleeding;
anal fissures.

Adverse reactions

During therapy, the following side effects of Meloxicam may be observed:

intestinal disorders;
nausea and vomiting;
gastrointestinal perforation;
gastritis;
colitis;
belching;
flatulence;
thrombocytopenia, leukopenia;
rash and itching of the skin;
epidermal necrolysis;
tinnitus;
confusion;
drowsiness;
headaches;
hypertension;
hot flashes;
increased heart rate;
renal failure (rare);
visual impairment;
allergic reactions.

Such effects from taking the drug rarely occur. As a rule, they appear in situations where the patient exceeds the duration of use of the drug or independently increases its dosage.

If adverse reactions occur, you should immediately stop using Meloxicam and consult a doctor.

During pregnancy and lactation

Meloxicam is not recommended for use during pregnancy. This is due to the fact that the drug has a teratogenic effect, that is, it can cause deformities or death of the fetus. Taking the drug in the third trimester of pregnancy can cause post-term pregnancy and complications during childbirth (weak labor, poor cervical dilatation, etc.).

During pregnancy, the use of Meloxicam in all forms of its release is contraindicated.

It is also not recommended to take the medicine when breastfeeding, since its active components penetrate into milk and in high dosages can cause developmental delays in the child and the occurrence of various pathologies.

Alcohol compatibility

The instructions do not provide information about the compatibility of Meloxicam and alcohol. However, doctors strongly recommend giving up alcohol during treatment. Despite the fact that Meloxicam and alcohol do not interact directly, when taken simultaneously, the load on the liver and excretory system increases.

After ethyl alcohol penetrates into the blood, the liver begins to actively produce enzymes that break down ethanol molecules and facilitate their removal from the body. Meloxicam is a complex chemical compound that also affects the functionality of the liver, speeding up and complicating its work. Since it is the liver that cleanses the body of breakdown products and drug toxins.

Thus, it turns out that when Meloxicam is compatible with alcohol, the organ begins to experience double load and work “for wear and tear”. And since long-term use of the drug is recommended for chronic pathologies, acute liver failure may occur with frequent consumption of alcoholic beverages. And in order to avoid negative consequences, it is not recommended to drink alcohol during treatment with Meloxicam.

Analogues

The cost of Meloxicam depends on the form of its release:

tablets – 295 rubles;
injections for intramuscular administration – 250 rubles;
rectal suppositories – 230 rubles.

But there are analogues of Meloxicam on the market. Among them are imported substitutes and Russian analogues. They also have different release forms. If we talk about the most effective means, it is worth highlighting the following:

in the form of injections - Amelotex, Artrosan, Loxidol, Melbek, Milixol;
in tablets - Movalis, Bi-xicam, Mirlox, Amelotex, Movalgin.

If we talk about which analogues are cheaper, then it is necessary to note:

Melox – tablets – 120 rubles;
Movasin - tablets - 90 rubles, ampoules - 100 rubles;
Diclofenac – tablets – 70 rubles, ampoules – 90 rubles;
Revmoxicam – tablets – 200 rubles;
Liberum - tablets - 90 rubles, ampoules - 110 rubles.

All these drugs are cheaper than Meloxicam and have a similar composition. However, replacing the original with Meloxicam analogs is possible only with the permission of the attending physician, since each of these drugs has its own list of contraindications.

The drug Meloxicam (Latin name Meloxikam) is a broad-spectrum anti-inflammatory drug. It does not contain steroids and can be suitable for patients with almost any problem - relieve pain and swelling, reduce inflammation and reduce fever to normal. But it should be used in strict consultation with your doctor and after carefully reading the instructions.

Composition and release form

The drug contains the active substance meloxicam, which is a derivative form of enolic acid and belongs to the category of oxicams. Depending on the form of release of the drug, its composition also differs slightly.

Meloxicam is produced and sold in the following forms:

pills;
rectal suppositories (suppositories);
sterile liquid in ampoules for injections.

Colloidal silicon dioxide (Aerosil 380), gelatinized starch 1500, as well as magnesium stearate, sodium citrate dihydrate and MCC can be used as additional substances.

Most Popular Meloxicam tablet form. Each pale yellow tablet is round in shape with a dividing notch on one side. They are packaged in special blisters of 10 pcs. The cardboard box contains instructions for use and 2 blisters. Sometimes there is packaging in plastic jars of 20 pieces. The content of the drug in each tablet depends on the variety - 7.5 or 15 mg.

Injection solution transparent yellow-green color is available in ampoules of 1.5 ml. The special packaging contains 3 or 5 units. The fluid is injected intramuscularly.

Rectal suppositories contain 15 mg of meloxicam and are packaged in 6 or 12 white or yellowish suppositories in one package.

The drug is released in the following countries:

Russia;
Greece;
China;
Israel;
India;
Vietnam.

To purchase the drug, you will need a prescription from your attending physician: without it, the drug will not be dispensed at points of sale.

Pharmacological properties

Meloxicam has pronounced analgesic properties, prevents the onset of inflammatory processes and relieves pain. Due to rapid dissolution in digestive acids and enzymes in the stomach, it penetrates the blood and binds to its proteins within 15 minutes after taking the tablet orally.

Rectal suppositories also act quickly. Injection administration can significantly shorten the period until a noticeable effect appears, since the drug penetrates even faster through muscle tissue into the circulatory system and begins its effect.

The drug slows down the process of synthesizing prostaglandins at the site of inflammation without damaging the mucous surface of the walls of the gastrointestinal tract. Such therapy does not threaten the patient with the appearance of ulcers. Meloxicam inhibits the enzymatic activity of cyclooxygenase, the selectivity of which is significantly reduced with prolonged use of the maximum permissible doses of the drug.

5-6 hours after a single dose of the drug, its concentration in the body is maximum, then it decreases and the drug is gradually eliminated, but does not cease to act.

During metabolism, Meloxicam enters the liver and is destroyed almost completely - 96%. Decomposition products are easily eliminated through the urinary system in literally two days, so there is no accumulation of either the substance itself or its constituent components in the body, regardless of the dosage regimen and dosage regimen.

Indications

The list of diseases that Meloxicam helps with is extensive. More often than other drugs, it is prescribed for various painful pathologies of the joints.

The use of this medicine is very effective in relieving pain and swelling in the following diseases:

rheumatism;
rheumatoid arthritis;
osteoarthritis and osteochondrosis;
Bekhterev's disease - ankylosing spondylitis;
various bruises and sprains of articular ligaments;
chronic polyarthritis.

It is also indicated for any other inflammation of the joints and periarticular tissues, accompanied by severe pain and degenerative processes. Due to its antipyretic effect, Meloxicam is successfully used for acute respiratory infections, fevers of various etiologies and local fevers. The analgesic properties of the active substance are actively used in the fight against pain of any origin, including toothache.

Indications for the use of tablets are similar to those for the solution in ampoules. Suppositories can be prescribed for local relief of pain near the anus caused by inflammatory processes occurring there.

Instructions for use, dosage

The amount of the drug for one-time use and the frequency of its use per day are prescribed by the doctor based on the patient’s diagnosis, his age category and individual characteristics.

General intake regimens look like this:

Reception tablet form recommended with meals, dosage from 7.5 to 15 mg per day. If the patient has kidney disease or pathologies of their development, then the maximum permissible amount for consumption per day should not exceed 7.5 mg.
Deep intramuscular injections can be prescribed to both adults and children over 15 years of age. The first injections should contain no more than 7.5 mg of active substance per day, then you can increase it to 15 mg, and after 3-4 days of therapy switch to tablets with a similar content of meloxicam.
Reception suppositories Let's say at a dosage of 7.5 mg once a day. As an exception, you can increase the dose to 15 mg, but in no case higher.

For various diseases, the daily dose can be varied depending on the achieved treatment result and the recommendations of the treating specialist.

Contraindications

Despite the high quality of treatment with Meloxicam, there are many more contraindications to its use than the scope of permissible use. In view of this, before using the drug, a doctor’s prescription and strict adherence to the instructions are required.

Cases where the drug is strictly prohibited for use include the following diseases and conditions:

acute course of gastrointestinal ulcer;
the risk of internal bleeding in the gastrointestinal tract;
individual intolerance to the components of the drug or special sensitivity to this and other anti-inflammatory non-steroidal drugs;
severe liver failure, as well as currently active liver diseases;
severe active kidney disease;
period of pregnancy and lactation;
postoperative phase after coronary artery bypass surgery;
inflammatory processes in the gastrointestinal tract;
age up to 15 years;
hyperkalemia is an excess of the normal level of potassium in the blood, confirmed by an electrocardiogram.

There are also cases when the use of Meloxicam is possible, but the dosage must be calculated very carefully, and when taking it, carefully monitor the patient’s well-being. In such situations, it is necessary to weigh all the pros and cons of using this medication, and if the positive effect greatly covers the degree of risk, then this drug is prescribed.

coronary heart disease;
cerebrovascular disorders;
chronic heart failure;
diabetes mellitus of all types;
peripheral arterial disease;
severe somatic illnesses;
the patient has a history of stomach and intestinal ulcers;
dyslipidemia;
infectious lesions of the body with the bacterium H. Pulori;
alcoholism and severe dependence on smoking or other drugs.

In addition, the risk category also includes elderly people, as well as patients taking similar non-steroidal drugs for a long time. You should not prescribe the drug in cases of simultaneous use of antiplatelet agents, anticoagulants, selective serotonin reuptake inhibitors and glucocorticosteroids.

Rectal suppositories, in addition, have specific contraindications associated with the risk of bleeding and inflammatory diseases in the rectum, both at the time of administration and in history.

Side effects and overdose

When the dose is increased or the body becomes sensitive to the drug, side effects of various types may occur. As a rule, their manifestation is characterized by instability and short duration - after stopping the intake or reducing the dose, everything returns to normal.

The following body reactions to intramuscular injections of Meloxicam may occur:

From the respiratory system An acute asthmatic attack may develop.
Urinary system may react with kidney problems.
The ability may be temporarily lost clearly perceive the world around you In addition, corneal conjunctivitis may develop.
Reaction skin most often manifests itself in the appearance of a rash, accompanied by itching and redness, as well as increased sensitivity of the skin to ultraviolet radiation.
Maybe increased blood pressure and increased heart rate, less often - the appearance of edema.
Appears frequently headache and dizziness, as well as tinnitus, spatial disorientation and drowsiness. Occasionally, confusion may occur.
From the gastrointestinal tract Possible inflammatory processes in the oral cavity, stomach pain, diarrhea or constipation, nausea, vomiting, the development of gastritis and peptic ulcers of the stomach and intestines, as well as flatulence.
Blood-forming organs may react to Meloxicam with manifestations of thrombocytopenia, anemia or leukopenia.

Tablet form The drug threatens with generally the same side effects, although there are still some differences:

From the digestive tract may occur: gastroduodenal ulcer, foul-smelling belching, increased activity of liver transaminases, hidden internal bleeding, hyperbilirubinemia, hepatitis, colitis, and sometimes gastrointestinal perforation and stomatitis.
On the skin Sometimes reactions such as erythema multiforme, Stevens-Johnson syndrome, toxic necrolysis of the epidermis, and bullous rash may occur.
From the nervous system possible confusion, vertigo and instability of the emotional state, manifested in sudden unpredictable mood swings, often without objective reasons.
When exposed to respiratory system the drug can provoke bronchospasm.
Urinary system may respond to taking tablets with an increase in blood urea levels and hypercreatininemia, and sometimes with the manifestation of albuminuria, hematuria and interstitial nephritis. In addition, acute renal failure may develop while taking Meloxicam. Urination will be difficult and painful.
Taking this medication may cause allergic reactions, such as anaphylactic shock or angioedema.
Maybe febrile state- fever and associated syndromes.

If any of these symptoms occur due to the use of Meloxicam, you must stop taking the drug. An overdose of a drug causes the same symptoms, only to a more severe degree.

To get rid of unpleasant consequences, it is necessary to rinse the stomach as soon as possible, since the absorption of the drug occurs very quickly, and also take absorbent medications, for example regular activated carbon, which will reduce the concentration of the active substance in the body and reduce the severity of side effects.

Special instructions

There are some important instructions to take into account before using the product. First of all, Meloxicam should never be taken with alcohol: this can cause the development of irreversible processes in the liver, kidneys and gastrointestinal tract.

The use of the drug and similar medications can affect fertility; women must take this into account when planning to conceive. Meloxicam can hide the symptoms of infectious and viral diseases.

Taking the drug may negatively affect the ability to concentrate, so it should be taken with caution by people whose work requires concentration.

Interaction with other drugs

When using other medications simultaneously, compatibility with Meloxicam must be taken into account. In particular, use together with diuretics, as well as Cyclosporine, can cause renal failure, and the joint use of lithium preparations will cause its accumulation in the body, and consequently, poisoning.

There are other dangerous combinations of drugs with Meloxicam and its analogues:

The effect of antihypertensive drugs on the body will be significantly reduced when taking this medication.
The risk of bleeding increases when taking blood thinning medications.
Myelotoxic drugs can increase the severity of hepatotoxicity of Meloxicam.
Methotrexate in this combination will cause the development of leukopenia.
The drug Meloxicam is not recommended to be taken with other drugs of the same group, since the risk of developing peptic ulcers of the entire gastrointestinal tract, from the oral cavity to the rectum, increases significantly. The same applies to taking acetylsalicylic acid.
When taking medication with diuretics, it is necessary to significantly increase the amount of fluid consumed.

In addition to the risky combinations of medications that have already been studied, there are still unknown ones, so you can combine the drug with any other types of medications only under the supervision of your doctor.

Drug analogues and prices

There are quite a lot of drugs similar in content of the active substance. They differ slightly in composition; the main differences are in price and manufacturer.

The main analogues of Meloxicam are the following:

- the average cost ranges from 150 to 170 rubles.
Amelotex- the price of the drug in tablets is from 135 rubles, in ampoules - 400 rubles.
Bi-xicam- from 140 rub.
Melbek- cost from 230 rubles.
Mataren will cost the buyer an average of 285 rubles.
Meloflam- price from 300 rubles. Contains dimexide as an excipient.
Meloflex Rompharm- costs from 210 to 325 rubles in various pharmacies.
Melox- 450 rub.
Meloxicam Prana, Pfizer, Sandoz, Tev, Avexim, RLS, Xefok- from 170 to 500 rubles.
Movalis- from 200 rub.
Movasin- 315 rub.
Mesipol- 180 rubles.
Mixol Od- 265 rub.
Mirlox- the cost does not exceed 200 rubles.
Movix- the price of the drug is approximately 340 rubles.
Exen Sanovel- 500 rub.

Thus, the price of Meloxicam and its analogues ranges from 130 to 500 rubles. In addition, when purchasing, you need to pay attention to the dosage - it also greatly affects the cost, as well as the auxiliary components, in order to take into account the body’s reaction to them.

Sometimes Meloxicam is replaced Nimesulide. This is due to the lack of the necessary medicine in the pharmacy at the moment, a similar effect on the body and a relatively low cost. Which drug is better is up to the patient to decide. The difference between these medications is small, but in case of individual intolerance to Meloxicam, you have to look for a replacement, and Nimesulide is perfect for this role.

Analogues of Meloxicam are also used in veterinary medicine. For example, there is a popular drug Meloxivet in suspension for cats and dogs. Its principle of action is the same - it is an analgesic, antipyretic and anti-inflammatory agent.

– an effective non-steroidal drug that relieves inflammation and copes with severe pain. This annotation will tell you for which diseases this drug can be used. You will find out what contraindications and side effects Meloxicam has.

Indications for use of the drug

Doctors often prescribe the drug to relieve attacks of pain and inflammation. What else does the drug help with? The medicine does not treat the underlying cause of the disease, but it helps to cope with an unpleasant symptom. Here are the purposes for which Meloxicam can be used:

Relieve pain during exacerbations of arthrosis;
For long-term treatment of polyarthritis;
Suitable for the treatment of rheumatoid arthritis;
Used for ankylosing spondylitis.

How to take medications correctly

Doctors prescribe the drug 1 tablet per day. The medicine should be taken with at least 250 ml of water. Sometimes the dose can be changed, but only after a doctor's prescription.

The injection solution is used for intramuscular administration. Doctors prohibit intravenous Meloxicam injections. Typically, injections are used for the first days of therapy to relieve severe pain quickly and effectively. After this, you can stop treatment with the solution and switch to Meloxicam tablets.

For exacerbation of pain due to arthrosis, doctors prescribe a dose of 7.5 mg once a day. If the medicine has little therapeutic effect for the patient, the doctor may increase the dosage to 15 mg. It is strictly prohibited to prescribe such doses on your own. The doctor may also prescribe the drug in the form of a gel or ointment.

If the patient has ankylosing spondylitis or rheumatoid arthritis, then the doctor immediately prescribes a dosage of 15 mg of Meloxicam per day. If the drug relieves pain quickly, then doctors may reduce the dose to 7 mg. In no case should the dose of the drug be exceeded by more than 15 mg. In any case, the duration of treatment and the dose of the drug are determined by the attending physician.

How to use the drug for special categories of patients

Doctors prescribe a dose of 7.5 mg per day to dialysis patients. If a person has problems with the kidneys and liver, the dosage should not exceed 7.5 mg. If any side effects occur, you should immediately stop injecting Meloxicam. How long the course of treatment will be is decided by the attending physician - do not self-medicate!

Elderly people should be prescribed no more than 7.5 mg, even with ankylosing spondylitis and arthritis. Even if the effect of the drug is small, you still should not exceed the dosage. Otherwise, severe side effects may occur.

Side effects of the medicine

Doctors should warn patients about the possible side effects of Meloxicam. They can occur due to a high dose or when the body is intolerant to the composition of the drug.

Where does it occur?	Side effect
These are the side effects that occur in the circulatory system.	Changes in blood tests; The occurrence of leukopenia; Thrombocytopenia; Agranulocytosis disease; Anemia often occurs.
Such complications may begin in the nervous system.	The patient has a headache; The person loses consciousness; There is a strong ringing in the ears; Feeling dizzy; Frequent sleepiness during the day; Mood swings; Sudden confusion; Nightmares at night.
Such changes and side effects occur in digestion.	Unpleasant sensations in the stomach; Flatulence; The patient constantly feels sick and vomits; Diarrhea or constipation often occurs; Manifestation of ulcers in the stomach; Bleeding; The occurrence of stomatitis; Sometimes esophagitis occurs; Colitis or gastritis rarely occurs.
Such side effects occur in the cardiac system.	Increased pressure; Severe tachycardia; The patient feels heat in the body; Subcutaneous vessels dilate.
The urinary zone of the body may experience its own side effects.	The functioning of the kidneys is impaired; Kidney failure begins; Increased serum creatinine concentration.
Side effects on the skin.	Allergies on the body; Severe itching; Skin rash often appears; Hives; The occurrence of Lyell's syndrome; Swelling in the mucous membrane area; Manifestation of erythema multiforme; Stevens-Johnson syndrome.
Other unpleasant symptoms from side effects may also occur.	Swelling on the skin; Hepatitis; The patient has decreased vision; Individual sensitivity to the composition of the drug.

The respiratory system is rarely affected. Sometimes bronchial asthma can occur only if the patient is allergic to nonsteroidal drugs.

Severe side effects in the stomach occur in elderly patients. They may develop bleeding, peptic ulcers, or perforation. Therefore, Meloxicam should be prescribed to such patients with special caution.

Any side effect should be reported to your doctor. Perhaps he will reduce the dosage of Meloxicam or prescribe another analgesic. Symptoms of side effects can be dangerous if not reported to a specialist in time.

Contraindications to taking the medicine

Sometimes the drug Meloxicam can greatly harm the body in specific cases. That is why the doctor first examines the patient, and only then prescribes treatment. The doctor will under no circumstances prescribe Meloxicam for the following diseases:

Ulcers in the digestive zone in the acute stage;
Patient sensitivity to the composition of the drug. Allergy to aspirin and acetylsalicylic acid;
Bleeding in the stomach;
Pregnancy;
Breastfeeding period;
Failure of the liver and kidneys;
The occurrence of bleeding in other organs;
Prohibited for children under 15 years of age;
Patient has heart failure.

If you know of any diseases in the body, be sure to tell your doctor. He will immediately decide whether you can take Meloxicam or whether the therapy will be dangerous to your health.

Drug overdose

If the patient exceeds the prescribed dose of Meloxicam, side effects will begin to appear in the body. Here are some signs of an overdose of the drug:

Nausea accompanied by vomiting;
A sharp feeling of drowsiness;
Stomach ache;
Bleeding in the stomach rarely occurs.

If the patient is poisoned with a large dose of Meloxicam, then the following dangerous complications will appear:

Increased pressure;
Increased breathing;
Acute renal failure;
The occurrence of seizures;
Collapse;
Liver dysfunction.

In case of severe poisoning with the drug, the following dangerous consequences can occur:

Heart failure;
The patient falls into a coma;
Anaphylactoid shock.

If the patient has taken too large a dose of medication, then the doctor prescribes symptomatic therapy. You need to be under the supervision of a specialist until all unpleasant symptoms subside. In extreme cases, you need to administer 4000 mg of cholestyramine, then the drug Meloxicam will be eliminated from the body faster.

Interaction with other drugs

You need to know what effects Meloxicam gives when taking other drugs in parallel. To prevent complications in the body, you must tell your doctor what medications you are currently taking. They may not be compatible with the composition of Meloxicam and cause side effects. Here are some examples of concurrent use of drugs:

If you give Meloxicam injections with lithium drugs, then their concentration in the blood will increase to a dangerous, toxic level. As a last resort, these medications can be prescribed, but only under the close supervision of a doctor. It is imperative to monitor the level of lithium in the blood;
Taking cholestyramine will reduce the period of elimination of Meloxicam from the body. Doctors categorically prohibit taking such drugs together;
The drug Methotrexate will increase all the negative side effects of Meloxicam on the body and on the properties of the blood. There is a risk of anemia or leukopenia;
You should not take non-steroidal medications together with Meloxicam;
If the patient combines the medicine with diuretics, then during the day you need to drink plenty of fluids. At this point, the doctor must monitor the condition of the patient’s kidneys;
When taking thrombolytic drugs together with Meloxicam, the risk of bleeding increases;
If the patient takes salicylic acid in parallel with the drug, then a peptic ulcer may develop in the digestive tract;
When taking ACE together with Meloxicam, acute renal failure may occur;
Taking oral medications leads to bleeding of any organs and damage to the intestinal mucosa;
The effect of hormonal contraceptives is reduced with parallel use of Meloxicam;
The effect of cyclosporine in the body is enhanced.

Release form of the medicine

Now you can buy Meloxicam in a pharmacy in the following forms:

Tablets of 15 or 7 mg. Sold in packs of 20 pieces;
Anti-inflammatory solution for injections and suspensions in ampoules. Sold in 5 ampoules of 1.5 ml.
The drug can also be in the form of an ointment, gel or suppository.

How to properly store the drug?

Composition of the drug: description

Meloxicam tablets contain the following active ingredients:

The main active ingredient is meloxicam – 15 mg;
Starch;
Lactose extract;
Silicon dioxide;
Sodium;
Magnesium;
A little cellulose.

The composition of the liquid for injection and injections includes:

Active ingredient: meloxicam – 15 mg;
Meglumin;
Sodium;
Glycine;
Pure water for injection;
Glycofurol;
Poloxamer.

Alcohol compatibility

Nonsteroidal anti-inflammatory drugs (NSAIDs), such as Meloxicam, are most often prescribed to people with joint inflammation. In addition, due to their medicinal properties, medications in this group can be used as antipyretics and pain relievers.

NSAIDs work by blocking the substance prostaglandin, which is responsible for the inflammatory process in the body. Thus, the effect of these medications stops the pain process. However, a little-known fact is that NSAIDs have an extremely negative effect on the mucous membrane of the gastrointestinal tract, and, therefore, combining such drugs with alcohol intake is highly undesirable.