Gyno tardiferon application. Tablets Gyno-tardiferon antianemic drug - “How to increase hemoglobin during pregnancy and breastfeeding? Gyno-tardiferon will help avoid anemia

In this article you can read the instructions for use of the drug Tardiferon. Reviews of site visitors - consumers of this medicine, as well as the opinions of specialist doctors on the use of Tardiferon in their practice are presented. We kindly ask you to actively add your reviews about the drug: whether the medicine helped or did not help get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Analogs of Tardiferon and Gyno-Tardiferon in the presence of existing structural analogues. Use for the treatment of iron deficiency and iron deficiency anemia in adults, children, as well as during pregnancy and lactation.

Tardiferon- an antianemic drug, the effect of which is determined by the properties of the components included in its composition.

Iron sulfate is a salt of iron, a trace element necessary for the synthesis of hemoglobin. Iron is part of hemoglobin, myoglobin and a number of enzymes. When using iron in the form of salts, its deficiency in the body is quickly replenished, which leads to a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, soreness and dry skin) and laboratory symptoms of anemia.

Mucoproteosis ensures better tolerability of the drug and increases the bioavailability and gradual release of ferrous iron (Fe2+) from the drug.

Ascorbic acid helps improve iron absorption.

Folic acid (in the drug Gino Tardiferon) is necessary for the normal maturation of megaloblasts and the formation of normoblasts. Stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines and pyrimidines, and in choline metabolism. During pregnancy, it protects the body from the effects of teratogenic factors.

The special neutral coating of the tablets ensures the absorption of the active components, mainly in the distal small intestine. The absence of local irritation on the gastric mucosa contributes to good tolerability of the drug in the gastrointestinal tract.

Compound

Iron sulfate + excipients (Tardiferon).

Iron sulfate hydrate + Folic acid (vitamin Bc) + excipients (Gyno-Tardiferon).

Pharmacokinetics

After taking the drug orally, iron is absorbed from the gastrointestinal tract. The bioavailability of iron is 10-30%. The gradual release of iron allows its absorption to be prolonged, mainly in the distal small intestine. Folic acid is absorbed primarily from the upper gastrointestinal tract (duodenum). Iron binding to plasma proteins is 90% or more. Deposited in the form of ferritin or hemosiderin in the cells of the phagocytic macrophage system, a small amount - in the form of myoglobin in muscles. The binding of folic acid to plasma proteins is 64%; biotransformation occurs in the liver. Iron is excreted in feces, urine and sweat. Folic acid is excreted mainly by the kidneys, partially through the intestines.

Indications

treatment and prevention of iron deficiency conditions of various etiologies (including during pregnancy and lactation, decreased absorption of iron from the gastrointestinal tract, prolonged bleeding, inadequate and unbalanced nutrition).

Release forms

Extended-release tablets (retard), sugar-coated (Tardiferon and Gino-Tardiferon).

There were no other dosage forms, be it drops or solution, at the time of publication of the drug in the Directory.

Instructions for use and dosage

Tardiferon

Adults and children over 6 years of age: take the tablets orally (without chewing). It is advisable to take the drug with water, before or during meals. Use for medicinal purposes: children over 6 years old - 1 tablet per day, children over 10 years old and adults - 1-2 tablets per day.

Use for preventive purposes: pregnant women - 1 tablet per day or every other day during the last two trimesters of pregnancy (or starting from the 4th month).

Duration of admission

Adult patients should take the drug for a period that ensures correction of anemia and restoration of iron reserves in the body. The dose for women is 600 mg, for men - 1200 mg.

For iron deficiency anemia, the duration of use is from 3 to 6 months, depending on the degree of depletion of the iron reserve: if necessary, in the absence of adequate control of anemia, it is necessary to increase the duration of use of the drug.

Gyno Tardiferon

For mild anemia, the drug is prescribed 1 tablet per day before breakfast; for moderate anemia - 1 tablet 2 times a day; in case of severe anemia - 1 tablet 3 times a day for several weeks (on average 4-5 weeks) - until normal hemoglobin levels are restored. After restoring normal hemoglobin levels, the drug should be continued for 2-3 months to replenish iron reserves.

To prevent iron and folic acid deficiency during pregnancy and lactation, the drug is prescribed 1 tablet per day in the 2nd and 3rd trimesters and the postpartum period during breastfeeding.

Side effect

nausea;
epigastric pain;
diarrhea, constipation.

Contraindications

anemia not associated with iron or folic acid deficiency (hemolytic anemia, megaloblastic anemia associated with isolated vitamin B12 deficiency);
increased iron content in the body (hemosiderosis);
violation of iron utilization mechanisms (anemia caused by lead poisoning, sideroachrestic anemia);
fructose intolerance, glucose and galactose malabsorption syndrome, invertase/isomaltase deficiency syndrome;
esophageal stenosis and/or obstructive changes in the gastrointestinal tract;
children's age (under 6 years for Tardiferon and under 18 years for Gyno-Tardiferon);
hypersensitivity to the components of the drug.

Use during pregnancy and breastfeeding

Use of Tardiferon tablets for preventive purposes: pregnant women - 1 tablet per day or every other day during the last two trimesters of pregnancy (or starting from the 4th month).

To prevent iron and folic acid deficiency during pregnancy and lactation, the drug Gyno Tardiferon is prescribed 1 tablet per day in the 2nd and 3rd trimesters and the postpartum period during breastfeeding.

Use in children

Tardiferon is contraindicated in children under 6 years of age. Children over 6 years of age: take the tablets orally (without chewing). It is advisable to take the drug with water, before or during meals. Use for medicinal purposes: children over 6 years old - 1 tablet per day, children over 10 years old - 1-2 tablets per day.

Gyno Tardiferon is contraindicated in children and adolescents under 18 years of age.

Special instructions

Before starting drug therapy, it is necessary to determine the content of iron and ferritin in the blood serum.

During the period of taking the drug, it is necessary to take into account that coffee, milk, vegetables, and cereals reduce the absorption of iron.

During the period of taking the drug, a dark coloration of the stool may be observed, which is due to the excretion of unabsorbed iron and has no clinical significance.

The drug should be taken with caution in case of inflammatory bowel diseases, alcoholism, liver or kidney failure.

Due to the presence of sucrose in the drug, its use is contraindicated in persons with fructose intolerance, glucose and galactose malabsorption syndrome, or invertase/isomaltase deficiency syndrome (rare metabolic disorders).

Drug interactions

Reduce iron absorption:

antacid drugs containing aluminum, calcium, magnesium salts, calcium preparations, etidronic acid, drugs that reduce the acidity of gastric juice (including cimetidine);
medicines containing carbonates, bicarbonates, phosphates, oxalates;
pancreatin, pancreolipase.

Mutually reduce absorption when used together:

tetracyclines, D-penicillamine, tea, egg yolk.

If it is necessary to combine it with the drugs or foods listed above, iron supplements should be taken 1 hour before or 2 hours after their use.

Increases absorption:

ascorbic acid, ethanol (alcohol) (including increases the risk of toxic complications).

Iron supplementation in large doses reduces the absorption of zinc.

Should not be prescribed together with other iron preparations, incl. for parenteral use, to avoid overdose.

Analogues of the drug Tardiferon

Structural analogues of the active substance:

Hemophere prolongatum;
Gyno-Tardiferon;
Ferrogrademet.

Analogs for therapeutic effect (medicines for the treatment of iron deficiency):

Aktiferrin;
Actiferrin compositum;
Biovital;
Biofer;
Venofer;
Vitrum Superstress;
Vitrum Circus;
Hemofer;
Gyno-Tardiferon;
CosmoFer;
Likferr 100;
Maltofer;
Maltofer Fall;
Mirazenova;
Monofer;
Pikovit Yunik;
Sideral Forte;
Sorbifer Durules;
Merz special dragee;
Stress formula with iron;
Supradin Kids Junior;
Totema;
Fenyuls;
Ferlatum;
Ferlatum Fol;
Ferretab;
Ferrinate;
Ferro Folgamma;
Ferrogrademet;
Ferronal;
Ferroplex;
Ferrum Lek;
Heferol;
Enfamil Premium 2;
Enfamil with iron.

If there are no analogues of the drug for the active substance, you can follow the links below to the diseases for which the corresponding drug helps, and look at the available analogues for the therapeutic effect.

Latin name: Gyno-Tardyferon
ATX code: B03AE10
Active ingredient: Fe + folic acid
Manufacturer: Pierre Fabre Medicament (France)
Conditions for dispensing from a pharmacy: By prescription

Gyno-Tardiferon is a vitamin and mineral remedy that eliminates iron-folic deficiency and the anemia caused by it, helps to increase hemoglobin and normalize blood composition.

Indications for use

Gyno-Tardiferon is prescribed for the treatment and prevention of anemia caused by a lack of iron and folic acid, as well as:

To replenish the supply of substances
With an insufficiently balanced diet
During pregnancy or menopause
If the condition has caused problems with iron absorption
For prolonged or heavy bleeding.

Composition of the drug

The active components contained in one tablet are iron sulfate and folic acid, their content is 256.3 mg and 0.35 mg, respectively.

Additional components are substances that form the structure and shell of the medicinal product: vitamin C, mucoproteose, starch, magnesium stearate and trisilicate, castor oil, talc, beeswax, sucrose and other ingredients.

Medicinal properties

The action of Gino-Tardiferon is due to the properties of the active and additional substances it contains. The effectiveness of the product is also explained by the peculiarity of the tablets - they are long-acting, that is, iron is released gradually. Considering that the substance is poorly absorbed when taken normally, this problem is eliminated in Gyno-Tardiferon - it is absorbed almost in full.

Lack of iron and the resulting anemia can cause fetal hypoxia, developmental disorders, and termination of pregnancy:

Folic acid ensures the proper development of pregnancy, prevents its spontaneous termination, and promotes the proper development of the spinal cord in the fetus.
Mucoproteosis protects the mucous membranes of the gastrointestinal tract from damage by iron compounds and ensures a smooth release of the substance.
Vitamin C enhances the absorption of iron.

Release forms

Average price: 201.67 rub.

Gyno-Tardiferon is available in the form of tablets with prolonged action. Pills in a white or yellowish coat, biconvex. When a transverse fracture occurs, the contents are brown or brown in color. The tablets are placed in 10 pieces in a contour package. There are 3 plates in a cardboard box with accompanying instructions.

Directions for use

Gyno-Tardiferon is recommended for oral administration to adults and children from 7 years of age. The tablets should be swallowed without first chewing or sucking, and it is also undesirable to keep them in the mouth for a long time. If swallowed, drink with plenty of water. For preventive purposes, the drug is taken daily, one tablet - preferably in the morning on an empty stomach - before breakfast.

When treating anemia caused by iron deficiency, you should follow your doctor's prescriptions. If there are no recommendations, drink Gyno Tardiferon according to the instructions for use:

Children – 1 tablet every day
For adult patients - 1-2 pills, for severe conditions - 3 pieces during the day.

While taking Gyno-Tardiferon, you must regularly do a blood test to determine your hemoglobin level. After normalization of its content, the daily dose is reduced, the drug is continued to be taken for 1-3 months to replenish the deficiency and consolidate the result.

During pregnancy and pregnancy

Studies conducted on animals did not find pathologies in the offspring after taking increased doses of the drug. Similar experiments were not carried out on pregnant women, but clinical observations did not record cases of anomalies and pathologies in newborn children. Despite this, you should take Gyno-Tacridiferon during pregnancy and lactation only under the supervision of a physician.

Contraindications

The drug should not be used for:

Individual hypersensitivity to ingredients
Combination with other iron-containing products
Children under 7 years old
High concentration of iron
Anemia not caused by iron-folic deficiency
In case of iron metabolism disorders, lead poisoning
For esophageal stenosis and other gastrointestinal pathologies
Intestinal obstruction
Oncological diseases.

Precautions

During a therapeutic or prophylactic course, it is necessary to regularly check the iron concentration and hemoglobin level, and with long-term use, vitamin B12. In addition, you need to remember:

While taking Gyno-Tardiferon tablets, it is possible that constipation, flatulence, and bloating may develop due to the castor oil contained.
It is better to drink coffee, tea, milk, eat eggs, and dairy products 1-2 hours after taking the tablet, as these products impair the absorption of the active substance.
People with fructose intolerance, glucose-galactose malabsorption and diabetes mellitus are not recommended to take the drug due to the sucrose present in it.

Cross-drug interactions

The active substances of Gyno-Tardiferon can react with many drugs, which leads to a distortion of the therapeutic effect. Therefore, when treating with other drugs, the specifics of taking an antianemic drug must be discussed with your doctor.

The iron salts contained in the drug reduce the absorption of Tetracycline, Penicillamine and Penicillin, Levodopa, Sulfasalazine, Thyroxine, as well as zinc-containing products. At the same time, the absorption of Gyno-Tardiferon slows down.
Cholestyramine, preparations with calcium and magnesium suppress the absorption of Gyno-Tardiferon.
When combined with non-steroidal anti-inflammatory drugs, damage to the gastrointestinal tract increases.
Ascorbic and citric acids enhance the absorption of iron.
Tocopherol (vit. E) reduces the effect of ferrous sulfate.
Analgesics, antibiotics, sulfonamides, antiepileptic drugs, Neomycin, Tetracycline inhibit the absorption of folic acid.
Folic acid weakens the effect of oral contraceptives, Primidine, Sulfasalazine.

Side effects

Taking Gyno-Tardiferon can cause negative effects:

Allergic reactions
Hives, itching
Abnormal bowel movements, bloating, nausea, blackened stool
In rare cases - dyspepsia and gastritis
If tablets are chewed or resorbed, darkening of the teeth and mouth ulcers may occur.

If tablets get into the esophagus or respiratory tract (this happens when swallowing is impaired), there is a risk of ulcers and tissue necrosis at the location of the pill.

Overdose

If the recommended doses of Gyno-Tardiferon are observed, no cases of overdose have been recorded. It occurs when the duration of the treatment course is exceeded or a large number of Gyno-Tardiferon tablets are unintentionally swallowed.

Acute intoxication manifests itself:

Nausea with bouts of vomiting (possibly with blood)
Diarrhea, abdominal pain
Weakness, sticky sweat
Pale skin
Decreased blood pressure, tachycardia
Confusion
Signs of hyperventilation.

Severe conditions can result in the death of a person. The lethal dose is 180-300 mg of iron per kilogram of weight. But due to individual characteristics, 30 mg may be toxic. Iron poisoning is especially dangerous for young children; even 1 g of the substance can be toxic for them.

After the first manifestation of intoxication, the victim feels better, but after a few hours (4-6) deterioration occurs, manifested by Cheyne-Stokes breathing, kidney failure, oliguria (decreased urination), and blood clotting disorders.

The victim must induce vomiting or lavage the stomach to remove the tablets. Call an ambulance.

Conditions and shelf life

The drug can be used for 5 years from the date of release. To preserve properties, keep away from sources of heat, moisture and light, at room temperature not exceeding 25° C. Keep away from children.

Analogues

To replace Gyno-Tardiferon with another drug, consultation and prescription of a doctor is necessary.

Actiferrin Compositum

Ratiopharm International Gmbh (Germany)

Average price: No. 30 (caps.) – 258.10 rub., 30 ml – 315 rub.

In addition to the compound of iron and folic acid, the preparation contains D, L-serine - a hydroxyamino acid necessary for the construction of almost all proteins in the body. The action of the drug is aimed at eliminating the deficiency of substances and the pathological conditions provoked by it.

The drug is produced in several dosage forms:

The capsules are two-color, with the name of the medicine printed on one of the surfaces. The contents of the pills are a paste-like oily mass. Packed in blister packs of 10 pieces.
Drops for oral administration are a clear liquid, greenish or yellow in color, with a raspberry odor. The solution is bottled in 30 ml bottles made of light-protective glass.

Advantages:

Balanced composition
No prescription required.

Flaws:

Stool disorders
Stains are difficult to remove.

tab. prolong. actions, covering coated 256.3 mg+350 mcg: 30 pcs.
Reg. No.: 1864/96/01/07/12/15 dated 09/06/2012 - Valid

Extended-release film-coated tablets from white to light beige, biconvex, with a smooth surface; on the cross section - brown with white edging; black inclusions are possible.

* as part of the kernel
** as part of the shell

Excipients: core - ascorbic acid, mucoproteose (anhydrous), potato starch, eudragit S, dibutyl phthalate, povidone, talc, magnesium stearate, castor oil, magnesium trisilicate; shell - talc, titanium dioxide, white beeswax, solid paraffin, eudragit E, sucrose.

10 pcs. - blisters (3) - cardboard packs.

Description of the drug GYNO-TARDIFERON based on officially approved instructions for use of the drug and made in 2009. Update date: 11/09/2009

Pharmacological action

A combined antianemic drug, the effect of which is determined by the properties of the components included in its composition.

Iron sulfate is a salt of iron, a trace element necessary for the synthesis of hemoglobin. Iron is part of hemoglobin, myoglobin and a number of enzymes. When iron is used in the form of salts, its deficiency in the body is quickly replenished, which leads to a gradual regression of clinical (weakness, fatigue, dizziness, tachycardia, soreness and dry skin) and laboratory symptoms of anemia.

Folic acid is necessary for normal maturation of megaloblasts and the formation of normoblasts. Stimulates erythropoiesis, participates in the synthesis of amino acids, nucleic acids, purines and pyrimidines, and in choline metabolism. During pregnancy, it protects the body from the effects of teratogenic factors.

The special neutral coating of the tablets ensures the absorption of active components, mainly from the upper part of the small intestine. The absence of local irritation on the gastric mucosa contributes to good tolerability of the drug in the gastrointestinal tract.

Pharmacokinetics

After taking the drug orally, iron is absorbed from the gastrointestinal tract. The bioavailability of iron is 10-30%. The gradual release of iron allows its absorption to be prolonged, mainly in the distal small intestine. Folic acid is absorbed primarily from the upper gastrointestinal tract (duodenum). The connection of iron with plasma proteins is 90% or more. Deposited in the form of ferritin or hemosiderin in the cells of the phagocytic macrophage system, a small amount is deposited in the form of myoglobin in muscles. The binding of folic acid to plasma proteins is 64%; biotransformation occurs in the liver. Iron is excreted in feces, urine and sweat. Folic acid is excreted mainly by the kidneys, partially through the intestines.

Indications for use

treatment and prevention of iron deficiency anemia of various etiologies (including during pregnancy, with impaired absorption of iron from the gastrointestinal tract, with prolonged bleeding, with inadequate and unbalanced nutrition).

Dosage regimen

At mild anemia the drug is prescribed 1 tablet. daily before breakfast; at moderate anemia- 1 tab. 2 times/day; at severe anemia- 1 tab. 3 times a day for several weeks (on average 4-5 weeks) - until normal hemoglobin levels are restored. After restoring normal hemoglobin levels, the drug should be continued for 2-3 months to replenish iron reserves.

For prevention of iron and folic acid deficiency during pregnancy and lactation the drug is prescribed 1 tablet. daily in the second and third trimesters and the postpartum period during breastfeeding.

Contraindications for use

anemia not associated with iron or folic acid deficiency (hemolytic anemia, megaloblastic anemia associated with isolated deficiency of vitamin B 12);
increased iron content in the body (hemosiderosis);
violation of iron utilization mechanisms (anemia caused by poisoned lead, sideroachrestic anemia);
esophageal stenosis and/or obstructive changes in the gastrointestinal tract;
hypersensitivity to the components of the drug.

Special instructions

Before starting drug therapy, it is necessary to determine the content of iron and ferritin in the blood serum.

During the period of taking the drug, a dark coloration of the stool may be observed, which is due to the excretion of unabsorbed iron and has no clinical significance.

The drug should be taken with caution in case of inflammatory bowel diseases, alcoholism, liver or kidney failure.

tab. prolong. actions, covering coated, 256.3 mg+350 mcg: 30 pcs. Reg. No.: LS-000300

Clinical and pharmacological group:

Antianemic drug

Release form, composition and packaging

Extended-release film-coated tablets from white to light beige, biconvex, with a smooth surface; on the cross section it is brown in color with a white edge.

Excipients: ascorbic acid, mucoproteose (anhydrous), potato starch, eudragit S, dibutyl phthalate, povidone, talc, magnesium stearate, hydrogenated castor oil, magnesium trisilicate.

Shell composition: talc, titanium dioxide, white beeswax, solid paraffin, eudragit E, sucrose.

10 pcs. - blisters (3) - cardboard packs.

Description of the active components of the drug " Gyno-tardiferon ®»

Pharmacological action

A combined antianemic drug, the effect of which is determined by the properties of the components included in its composition.

Mucoproteose, being a natural high-molecular fraction obtained from the intestinal mucosa of animals and having a certain content of amino sugars and organically bound sulfate, provides better tolerability of the drug from the gastrointestinal tract and increases the bioavailability of iron ions. Ascorbic acid helps improve iron absorption. The special neutral coating of the tablets ensures the absorption of active components, mainly from the upper part of the small intestine. The absence of local irritation on the gastric mucosa contributes to good tolerability of the drug in the gastrointestinal tract.

Indications

- treatment and prevention of iron deficiency anemia of various etiologies (including during pregnancy, with impaired absorption of iron from the gastrointestinal tract, with prolonged bleeding, with inadequate and unbalanced nutrition).

Dosage regimen

At mild anemia the drug is prescribed no 1 tablet/day before breakfast; at moderate anemia- 1 tab. 2 times/day; at severe anemia- 1 tab. 3 times a day for several weeks (on average 4-5 weeks) - until normal hemoglobin levels are restored. After restoring normal hemoglobin levels, the drug should be continued for 2-3 months to replenish iron reserves.

For

Side effect

From the digestive system: rarely - nausea, epigastric pain, diarrhea, constipation.

Contraindications

- anemia not associated with iron or folic acid deficiency (hemolytic anemia, megaloblastic anemia associated with isolated deficiency of vitamin B 12);

- increased iron content in the body (hemosiderosis);

— violation of the mechanisms of iron utilization (anemia caused by lead poisoning, sideroachrestic anemia);

— stenosis of the esophagus and/or obstructive changes in the gastrointestinal tract;

- children's age (under 18 years);

- hypersensitivity to the components of the drug.

Pregnancy and lactation

For prevention of iron and folic acid deficiency during pregnancy and lactation the drug is prescribed 1 tablet/day in the second and third trimesters and the postpartum period during breastfeeding.

Use for liver dysfunction

The drug should be taken with caution in case of liver failure.

Use for renal impairment

The drug should be taken with caution in case of renal failure.

Application for children

Contraindicated in children under 18 years of age.

Special instructions

Before starting drug therapy, it is necessary to determine the content of iron and ferritin in the blood serum.

During the period of taking the drug, a dark coloration of the stool may be observed, which is due to the excretion of unabsorbed iron and has no clinical significance.

The drug should be taken with caution in case of inflammatory bowel diseases, alcoholism, liver or kidney failure.

Overdose

Symptoms: the manifestations of the described side effects may increase.

Treatment: gastric lavage with 1% aqueous solution of sodium bicarbonate, symptomatic therapy. The antidote is deferoxamine.

Drug interactions

Conditions for dispensing from pharmacies

The drug is available with a prescription.

Storage conditions and periods

Store at temperatures up to 25°C out of the reach of children. Shelf life - 5 years.

Drug interactions

Not compatible with other drugs:

Reduce absorption: antacid drugs, calcium supplements, etidronic acid, drugs that reduce the acidity of gastric juice (including cimetidine, drugs containing carbonates, bicarbonates, phosphates, oxalates), pancreatin, pancreolipase, coffee, tea, milk , vegetables, cereals, egg yolk (iron supplements should be taken 1 hour before or 2 hours after their use).

Increase absorption - ascorbic acid, ethanol (including increases the risk of toxic complications).

The drug reduces the absorption of fluoroquinolones, penicillamine, tetracyclines, and in large doses reduces the absorption of zinc preparations (they are recommended to be taken 2 hours before or 2 hours after taking an iron supplement).

A combined antianemic drug, the effect of which is determined by the properties of the components included in its composition.

Pharmacokinetics

Iron binding to plasma proteins is 90% or more. Deposited in the form of ferritin or hemosiderin in the cells of the phagocytic macrophage system, a small amount - in the form of myoglobin in muscles.

The binding of folic acid to plasma proteins is 64%; biotransformation occurs in the liver.

Iron is excreted in feces, urine and sweat.

Folic acid is excreted mainly by the kidneys, partially through the intestines.

Release form

Extended-release tablets, film-coated from white to light beige, biconvex, with a smooth surface; on the cross section it is brown in color with a white edge.

Excipients: ascorbic acid, mucoproteose (anhydrous), potato starch, eudragit S, dibutyl phthalate, povidone, talc, magnesium stearate, hydrogenated castor oil, magnesium trisilicate.

Shell composition: talc, titanium dioxide, white beeswax, solid paraffin, eudragit E, sucrose.

10 pcs. - blisters (3) - cardboard packs.

Dosage

For mild anemia, the drug is prescribed 1 tablet/day before breakfast; for moderate anemia - 1 tablet. 2 times/day; for severe anemia - 1 tablet. 3 times a day for several weeks (on average 4-5 weeks) - until normal hemoglobin levels are restored. After restoring normal hemoglobin levels, the drug should be continued for 2-3 months to replenish iron reserves.

Overdose

Symptoms: the manifestations of the described side effects may increase.

Treatment: gastric lavage with 1% aqueous solution of sodium bicarbonate, symptomatic therapy. The antidote is deferoxamine.

Interaction

Not compatible with other drugs:

Increase absorption - ascorbic acid, ethanol (including increases the risk of toxic complications).

Side effects

From the digestive system: rarely - nausea, epigastric pain, diarrhea, constipation.

Indications

treatment and prevention of iron deficiency anemia of various etiologies (including during pregnancy, with impaired absorption of iron from the gastrointestinal tract, with prolonged bleeding, with inadequate and unbalanced nutrition).

Contraindications

anemia not associated with iron or folic acid deficiency (hemolytic anemia, megaloblastic anemia associated with isolated deficiency of vitamin B 12);
increased iron content in the body (hemosiderosis);
violation of iron utilization mechanisms (anemia caused by lead poisoning, sideroachrestic anemia);
esophageal stenosis and/or obstructive changes in the gastrointestinal tract;
children's age (under 18 years);
hypersensitivity to the components of the drug.

Features of application

Use during pregnancy and breastfeeding

To prevent iron and folic acid deficiency during pregnancy and lactation, the drug is prescribed 1 tablet per day in the II and III trimesters and the postpartum period during breastfeeding.

Use for liver dysfunction

The drug should be taken with caution in case of liver failure.

Use for renal impairment

The drug should be taken with caution in case of renal failure.

Use in children

Contraindicated in children under 18 years of age.

Special instructions

Before starting drug therapy, it is necessary to determine the content of iron and ferritin in the blood serum.

During the period of taking the drug, a dark coloration of the stool may be observed, which is due to the excretion of unabsorbed iron and has no clinical significance.

The drug should be taken with caution in case of inflammatory bowel diseases, alcoholism, liver or kidney failure.